Product Name

  • Name

    Orciprenaline

  • EINECS 209-569-1
  • CAS No. 586-06-1
  • Article Data6
  • CAS DataBase
  • Density 1.199g/cm3
  • Solubility
  • Melting Point 100°
  • Formula C11H17 N O3
  • Boiling Point 417.5°Cat760mmHg
  • Molecular Weight 211.261
  • Flash Point 179.7°C
  • Transport Information
  • Appearance
  • Safety Poison by ingestion, intraperitoneal and intravenous routes. Moderately toxic by subcutaneous route. Human reproductive effects by ingestion: changes in the uterus, cervix and vagina. When heated to decomposition it emits toxic fumes of NOx.
  • Risk Codes
  • Molecular Structure Molecular Structure of 586-06-1 (Orciprenaline)
  • Hazard Symbols
  • Synonyms Benzylalcohol, 3,5-dihydroxy-a-[(isopropylamino)methyl]- (6CI,8CI); (?à)-Metaproterenol; (?à)-Orciprenaline;1-(3,5-Dihydroxyphenyl)-2-(isopropylamino)ethanol; 3,5-Dihydroxy-a-[(isopropylamino)methyl]benzylalcohol; Metaproterenol; Orciprenaline
  • PSA 72.72000
  • LogP 1.52010

Orciprenaline Chemical Properties

MF: C11H17NO3
MW: 497.11
EINECS: 223-375-4
Density: 1.199 g/cm3     
Flash Point: 179.7 °C 
Index of Refraction: 1.579 
Enthalpy of Vaporization: 70.73 kJ/mol 
Boiling Point: 417.5 °C at 760 mmHg 
Vapour Pressure: 1.02E-07 mmHg at 25°C 
IUPAC Name: 5-[1-hydroxy-2-(propan-2-ylamino)ethyl]benzene-1,3-diol
Synonyms: 5-(1-Hydroxy-2-propan-2-ylamino-ethyl)benzene-1,3-diol ;  5-[1-Hydroxy-2-(1-methylethylamino)ethyl]benzene-1,3-diol
Following is the molecular structure of Orciprenaline (CAS NO.586-06-1):

Orciprenaline Uses

 Orciprenaline (CAS NO.586-06-1) is used as Bronchodilators.

Orciprenaline Production

 Orciprenaline (CAS NO.586-06-1) Production methods: 3,5 - 2-acetic acid-based reaction of acetyl first with bromine and then reactes with isopropylamine muddle along - (3,5 - dihydroxyphenyl) -2 - isopropylamine B-one, be soluble in methanol, at room temperature with nickel catalyst hydrogenation, was iso Chuanning.

Orciprenaline Toxicity Data With Reference

1.    

orl-man TDLo:286 µg/kg

     AJMSA9    American Journal of the Medical Sciences. 291 (1986),168.
2.    

orl-rat LD50:3370 mg/kg

     TXAPA9    Toxicology and Applied Pharmacology. 8 (1966),353.
3.    

ivn-rat LD50:67,200 µg/kg

     TXAPA9    Toxicology and Applied Pharmacology. 8 (1966),353.
4.    

ipr-mus LDLo:240 mg/kg

     APTOA6    Acta Pharmacologica et Toxicologica. 31 (1972),33.
5.    

scu-mus LD50:406 mg/kg

     ARZNAD    Arzneimittel-Forschung. Drug Research. 26 (1976),1404.
6.    

ivn-mus LD50:86 mg/kg

     APTOA6    Acta Pharmacologica et Toxicologica. 38 (1976),474.
7.    

orl-dog LD50:125 mg/kg

     TXAPA9    Toxicology and Applied Pharmacology. 8 (1966),353.
8.    

ivn-dog LD50:30 mg/kg

     TXAPA9    Toxicology and Applied Pharmacology. 8 (1966),353.
9.    

orl-rbt LD50:3110 mg/kg

     TXAPA9    Toxicology and Applied Pharmacology. 8 (1966),353.
10.    

ivn-rbt LD50:81,300 µg/kg

     TXAPA9    Toxicology and Applied Pharmacology. 8 (1966),353.

Orciprenaline Safety Profile

Poison by ingestion, intraperitoneal and intravenous routes. Moderately toxic by subcutaneous route. Human reproductive effects by ingestion: changes in the uterus, cervix and vagina. When heated to decomposition it emits toxic fumes of NOx.
 

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