-
Name
oxametacin
- EINECS
- CAS No. 27035-30-9
- Article Data12
- CAS DataBase
- Density 1.35g/cm3
- Solubility
- Melting Point 181-182° (dec)
- Formula C19H17 Cl N2 O4
- Boiling Point °Cat760mmHg
- Molecular Weight 372.808
- Flash Point °C
- Transport Information
- Appearance
- Safety Poison by ingestion and intraperitoneal routes. An anti-inflammatory agent. When heated to decomposition it emits toxic fumes of Cl− and NOx.
- Risk Codes
-
Molecular Structure
- Hazard Symbols
- Synonyms Indole-3-acetohydroxamicacid, 1-(p-chlorobenzoyl)-5-methoxy-2-methyl- (8CI); Dinulcid; Flogar;Indoxamic acid; Oxametacin
- PSA 80.56000
- LogP 3.73900
Oxamethacin Chemical Properties
IUPAC Name: 2-[1-(4-Chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]-N-hydroxyacetamide
Synonyms of Oxamethacin (CAS NO.27035-30-9) : 1-(p-Chlorobenzoyl)-5-methoxy-2-methylindole-3-acetohydroxamic acid ;1H-Indole-3-acetamide, 1-(4-chlorobenzoyl)-N-hydroxy-5-methoxy-2-methyl- (9CI) ; Indole-3-acetohydroxamic acid, 1-(p-chlorobenzoyl)-5-methoxy-2-methyl- ; Oxametacin
InChI:InChI=1/C19H17ClN2O4/c1-11-15(10-18(23)21-25)16-9-14(26-2)7-8-17(16)22(11)19(24)12-3-5-13(20)6-4-12/h3-9,25H,10H2,1-2H3,(H,21,23)
CAS NO: 27035-30-9
Molecular Formula:C19H17ClN2O4
Molecular Weight :372.8023
Molecular Structure :.png)
EINECS: 248-179-6
Index of Refraction: 1.63
Surface Tension: 49.4 dyne/cm
Density: 1.35 g/cm3
Oxamethacin Uses
Oxamethacin (CAS NO.27035-30-9) is non-steroidal anti-inflammatory analgesic.
Oxamethacin Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 32mg/kg (32mg/kg) | Bollettino Chimico Farmaceutico. Vol. 114, Pg. 319, 1975. | |
| mouse | LD50 | oral | 92mg/kg (92mg/kg) | Bollettino Chimico Farmaceutico. Vol. 114, Pg. 319, 1975. | |
| rat | LD50 | intraperitoneal | 40mg/kg (40mg/kg) | Bollettino Chimico Farmaceutico. Vol. 114, Pg. 319, 1975. | |
| rat | LD50 | oral | 78mg/kg (78mg/kg) | Bollettino Chimico Farmaceutico. Vol. 114, Pg. 319, 1975. |
Oxamethacin Safety Profile
Poison by ingestion and intraperitoneal routes. An anti-inflammatory agent. When Oxamethacin (CAS NO.27035-30-9) is heated to decomposition, it emits toxic fumes of Cl− and NOx.
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View