Product Name

  • Name

    (diethyl)[3-phenyl-1,2,4-oxadiazole-5-ethyl]ammonium chloride

  • EINECS
  • CAS No. 1219-20-1
  • Density
  • Solubility
  • Melting Point 153-154°
  • Formula C14H19 N3 O . Cl H
  • Boiling Point 364.8°C at 760 mmHg
  • Molecular Weight 281.82
  • Flash Point 174.4°C
  • Transport Information
  • Appearance
  • Safety Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion and subcutaneous routes. When heated to decomposition it emits toxic fumes of NOx and HCl. See also AMINES and OXOLAMINE; OXOLAMINE CITRATE.
  • Risk Codes
  • Molecular Structure Molecular Structure of 1219-20-1 ((diethyl)[3-phenyl-1,2,4-oxadiazole-5-ethyl]ammonium chloride)
  • Hazard Symbols 3
  • Synonyms 1,2,4-Oxadiazole,5-[2-(diethylamino)ethyl]-3-phenyl-, monohydrochloride (8CI);1,2,4-Oxadiazole-5-ethanamine, N,N-diethyl-3-phenyl-, monohydrochloride (9CI);Oxolamine hydrochloride
  • PSA 42.16000
  • LogP 3.42290

Oxolamine hydrochloride Chemical Properties

IUPAC Name: Diethyl-[2-(3-phenyl-1,2,4-oxadiazol-5-yl)ethyl]azanium chloride
Synonyms of Oxolamine hydrochloride (CAS NO.1219-20-1): Diethyl-[2-(3-phenyl-1,2,4-oxadiazol-5-yl)ethyl]azanium chloride ; 5-(2-(Diethylamino)ethyl)-3-phenyl-1,2,4-oxadiazole hydrochloride ; 5-(2-Dietilaminoetil)-3-fenil-1,2,4-oxadiezolo cloridrato ; Oxolamina cloridrato ; Oxolamine HCl ;(Diethyl)(3-phenyl-1,2,4-oxadiazole-5-ethyl)ammonium chloride ; 1,2,4-Oxadiazole, 5-(2-(diethylamino)ethyl)-3-phenyl-, monohydrochloride
CAS NO: 1219-20-1
Molecular Formula: C14H20ClN3O
Molecular Weight: 281.7811
Molecular Structure :
EINECS: 214-940-6
H bond acceptors: 4
H bond donors: 0
Freely Rotating Bonds: 6
Polar Surface Area: 38.92 Å2
Flash Point: 174.4 °C
Enthalpy of Vaporization: 61.1 kJ/mol
Boiling Point: 364.8 °C at 760 mmHg
Vapour Pressure: 1.64E-05 mmHg at 25°C

Oxolamine hydrochloride Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 208mg/kg (208mg/kg)   British Journal of Pharmacology and Chemotherapy. Vol. 16, Pg. 209, 1961.
mouse LD50 intravenous 63mg/kg (63mg/kg)   British Journal of Pharmacology and Chemotherapy. Vol. 16, Pg. 209, 1961.
mouse LD50 oral 1061mg/kg (1061mg/kg)   Bollettino Chimico Farmaceutico. Vol. 109, Pg. 476, 1970.
mouse LD50 subcutaneous 465mg/kg (465mg/kg)   British Journal of Pharmacology and Chemotherapy. Vol. 16, Pg. 209, 1961.
rat LD50 intraperitoneal 185mg/kg (185mg/kg)   British Journal of Pharmacology and Chemotherapy. Vol. 16, Pg. 209, 1961.
rat LD50 intravenous 63mg/kg (63mg/kg)   French Medicament Patent Document. Vol. #683M,
rat LD50 oral 1650mg/kg (1650mg/kg)   British Journal of Pharmacology and Chemotherapy. Vol. 16, Pg. 209, 1961.
rat LD50 subcutaneous 465mg/kg (465mg/kg)   French Medicament Patent Document. Vol. #683M,

Oxolamine hydrochloride Safety Profile

Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion and subcutaneous routes. When Oxolamine hydrochloride (CAS NO.1219-20-1) is heated to decomposition, it emits toxic fumes of NOx and HCl. See also AMINES and OXOLAMINE; OXOLAMINE CITRATE.

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