Product Name

  • Name

    Dacomitinib (PF299804)

  • EINECS
  • CAS No. 1110813-31-4
  • Article Data9
  • CAS DataBase
  • Density 1.344
  • Solubility DMSO, Methanol (Sparingly)
  • Melting Point >187°C (dec.)
  • Formula C24H25ClFN5O2
  • Boiling Point 665.7±55.0 °C(Predicted)
  • Molecular Weight 469.94
  • Flash Point
  • Transport Information
  • Appearance White to Off-White Solid
  • Safety
  • Risk Codes
  • Molecular Structure Molecular Structure of 1110813-31-4 (Dacomitinib (PF299804))
  • Hazard Symbols
  • Synonyms PF299804; pf-00299804-03; (2e)-n-(4-((3-chloro-4-fluorophenyl)amino)-7-methoxy-6-quinazolinyl)-4-(1-piperidinyl)-2-butenamide; (E)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-Methoxyquinazolin-6-yl)-4-(piperidin-1-yl)but-2-enamide; pf-299
  • PSA 79.38000
  • LogP 5.23900

PF 00299804-03; (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-4-(1-piperidinyl)-2-Butenamide Specification

Dacomitinib is an Erb-inhibitor, or an inhibitor of the members of the epidermal growth factor receptor family. Used as an ant-cancer agent due to observation of over-expressed epidermal growth factor receptor in nearly all cases of squamous cell carcinoma in the head and neck.

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