Product Name: Potassium 3-[(8R,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3-oxo-2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-17-yl]propanoate
Synonyms: Aldadiene-potassium ; Canrenoate Potassium ;Canrenone free acid potassium salt ; Potassium 17-hydroxy-3-oxo-17alpha-pregna-4,6-diene-21-carboxylate ; Potassium 17-Hydroxy-3-oxo-17a-pregna-4,6-diene-21-carboxylate ; Potassium 3-(17-beta-hydroxy-3-oxoandrosta-4,6-dien-17-yl)propionate ; Potassium 3-[(8R,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3-oxo-2,3,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]propanoate (non-preferred name)
Molecular Structure :
Molecular Formula : C22H29KO4
Molecular Weight : 396.56
CAS NO: 2181-04-6
EINECS: 218-554-9
Appearance: Potassium canrenoate (CAS NO.2181-04-6) is color light yellow to tan powder.
Potassium canrenoate (CAS NO.2181-04-6) is for the metabolites of spironolactone Canrenoate acid potassium salt, role similar to spironolactone, but a lesser role in the feminization of male breast, it can be used as alternative medicine, mainly for heart failure, edema, and cirrhosis with ascites.
1. | mic-mus:lym 150 mg/L | ARTODN Archives of Toxicology. 61 (1988),201. | ||
2. | orl-rat LD50:650 mg/kg | NICHAS Nichidai Igaku Zasshi. 36 (1977),7. | ||
3. | ipr-rat LD50:183 mg/kg | IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 11 (1980),811. | ||
4. | scu-rat LD50:160 mg/kg | IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 11 (1980),811. | ||
5. | ivn-rat LD50:112 mg/kg | IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 11 (1980),811. | ||
6. | orl-mus LD50:740 mg/kg | NICHAS Nichidai Igaku Zasshi. 36 (1977),7. | ||
7. | ipr-mus LD50:140 mg/kg | AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. 149 (1964),8. | ||
8. | scu-mus LD50:165 mg/kg | IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 11 (1980),811. | ||
9. | ivn-mus LD50:125 mg/kg | IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 11 (1980),811. |
Poison by intravenous, subcutaneous, and intraperitoneal routes. Moderately toxic by ingestion. An experimental teratogen. Experimental reproductive effects. A steroid. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes of K2O.
Hazard Codes Xn
Risk Statements 22
R22: Potassium canrenoate (CAS NO.2181-04-6) is harmful if swallowed.
Safety Statements 36
S36:Wear suitable protective clothing.
WGK Germany 3
RTECS TU3500000
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