-
Name
Primaquine
- EINECS 201-987-2
- CAS No. 90-34-6
- Article Data17
- CAS DataBase
- Density 1.0313 (rough estimate)
- Solubility 718.4g/L(25 oC)
- Melting Point 25°C
- Formula C15H21 N3 O
- Boiling Point bp0.2 175-179°
- Molecular Weight 259.351
- Flash Point
- Transport Information
- Appearance
- Safety Poison by ingestion and intravenous routes. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
- Risk Codes
-
Molecular Structure
- Hazard Symbols
- Synonyms Quinoline,8-[(4-amino-1-methylbutyl)amino]-6-methoxy- (6CI,8CI); (?à)-Primaquine;6-Methoxy-8-[4-amino-1-methylbutylamino]quinoline;8-(4-Amino-1-methylbutylamino)-6-methoxyquinoline; NSC 27296; Neo-Quipenyl;Primachin; Primaquin; Primaquine; SN 13272; WR 2975; dl-Primaquine
- PSA 60.17000
- LogP 3.55600
PRIMAQUINE Chemical Properties
IUPAC Name: 4-N-(6-Methoxyquinolin-8-yl)pentane-1,4-diamine
Synonyms: 8-(4-Amino-1-methylbutylamino)-6-methoxyquinoline ; N-(6-Methoxyquinolin-8-yl)pentane-1,4-diamine
Molecular Structure: 
Molecular Formula: C15H21N3O
Molecular Weight : 259.35
CAS NO: 90-34-6
EINECS: 201-987-2
Index of Refraction: 1.616
Surface Tension: 48 dyne/cm
Density: 1.126 g/cm3
Flash Point: 226.6 °C
Enthalpy of Vaporization: 71.01 kJ/mol
Boiling Point: 451.1 °C at 760 mmHg
Vapour Pressure: 2.5E-08 mmHg at 25°C
Appearance: Primaquine (CAS NO.90-34-6) is viscous liquid.
Solubility: Primaquine (CAS NO.90-34-6) is soluble in ether.
PRIMAQUINE Uses
Primaquine (CAS NO.90-34-6) is effective drugs for teatment with vivax malaria and block all types of malaria transmission .
PRIMAQUINE Toxicity Data With Reference
| 1. | sce-rat-orl 8 mg/kg | SYXUD2 Shandong Yixueyuan Xuebao. Journal of Shandong Medical College 23 (1985),26. | ||
| 2. | orl-mus LD50:100 mg/kg | AMACCQ Antimicrobial Agents and Chemotherapy. 12 (1977),51. | ||
| 3. | ivn-mus LD50:15,900 µg/kg | ANTCAO Antibiotics and Chemotherapy. 12 (1962),103. |
PRIMAQUINE Safety Profile
Poison by ingestion and intravenous routes. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
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