Parathion-methyl Chemical Properties
Name:Parathion-methyl
Synonyms:O,O-Dimethyl O-(p-nitrophenyl) thionophosphate; Methyl parathion
Molecular Structure :
Molecular Formula:C
8H
10NO
5PS
Molecular Weight:263.20
EINECS:206-050-1
Density:1.36
Melting point:36 oC
Boiling point:143 oC (1.0 mmHg)
Flash point:46.1 oC
Water solubility:0.005 g/100 mL
Parathion-methyl Toxicity Data With Reference
1. | | mmo-sat 667 µg/plate | | ENMUDM Environmental Mutagenesis. 5 (Suppl 1)(1983),3. |
2. | | sce-hmn:lym 10 mg/L | | MUREAV Mutation Research. 88 (1981),307. |
3. | | orl-rat LD50:6 mg/kg | | 28ZPAK Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku Marhold, J.V.,Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu Praha,Czechoslovakia.: 1972,208. |
4. | | ihl-rat LC50:34 mg/m3/4H | | EGESAQ Egeszsegtudomany. 34 (1980),173. |
5. | | skn-rat LD50:63 mg/kg | | SPEADM Special Publication of the Entomological Society of America. 78-1 ,1978.38. |
6. | | ipr-rat LD50:2800 µg/kg | | APCRAW Advances in Pest Control Research. 4 (1961),117. |
7. | | scu-rat LD50:6 mg/kg | | JEENAI Journal of Economic Entomology. 50 (1957),356. |
8. | | ivn-rat LD50:9 mg/kg | | NTIS** National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) No. PB277-077 . |
9. | | orl-mus LD50:18 mg/kg | | 85GMAT Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure Izmerov, N.F., et al.,Moscow, USSR.: Centre of International Projects, GKNT,1982,59. |
10. | |
Parathion-methyl Consensus Reports
IARC Cancer Review: Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal No Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 30 ,1983,p. 131.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . NCI Carcinogenesis Bioassay (feed); No Evidence: mouse, rat NCITR* National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD 20014) No. NCI-CG-TR-157 ,1979. . EPA Genetic Toxicology Program. EPA Extremely Hazardous Substances List.
Parathion-methyl Safety Profile
Poison by inhalation, ingestion, skin contact, subcutaneous, intravenous, and intraperitoneal routes. Fatal poisoning can result from skin or eye contact after very brief exposure to concentrated solution. Experimental teratogenic and reproductive effects. Questionable carcinogen. Human mutation data reported. A cholinesterase inhibitor type of insecticide. When heated to decomposition it emits very toxic fumes of NO
x, PO
x, and SO
x. See also
PARATHION.
Parathion-methyl Standards and Recommendations
OSHA PEL: TWA 0.2 mg/m3 (skin)
ACGIH TLV: TWA 0.2 mg/m3 (skin); Not Classifiable as a Human Carcinogen
NIOSH REL: (Methyl Parathion) TWA 0.2 mg/m3
DOT Classification: 6.1; Label: Poison