Product Name

  • Name

    Difenamizole

  • EINECS
  • CAS No. 20170-20-1
  • Density 1.13g/cm3
  • Solubility
  • Melting Point 123-128°; mp 120-122°
  • Formula C20H22 N4 O
  • Boiling Point 543.6°Cat760mmHg
  • Molecular Weight 334.421
  • Flash Point 282.6°C
  • Transport Information
  • Appearance
  • Safety Moderately toxic by intraperitoneal and ingestion routes. An analgesic and anti-inflammatory agent. When heated to decomposition it emits toxic fumes of NOx.
  • Risk Codes
  • Molecular Structure Molecular Structure of 20170-20-1 (Difenamizole)
  • Hazard Symbols
  • Synonyms Propionamide,2-(dimethylamino)-N-(1,3-diphenylpyrazol-5-yl)- (8CI); AP 14; Difenamizole;Diphenamizole; Pasalin
  • PSA 50.16000
  • LogP 3.50090

Pasalin Chemical Properties

IUPAC Name: 2-(Dimethylamino)-N-(2,5-diphenylpyrazol-3-yl)propanamide
Synonyms of Pasalin (CAS NO.20170-20-1) : 1,3-Diphenyl-5-(2-dimethylaminopropionamido)pyrazole ; 2-(Dimethylamino)-N-(1,3-diphenyl-1H-pyrazol-5-yl)propanamide ; Difenamizol ; Difenamizolum ; Pasalin ; Propanamide, 2-(dimethylamino)-N-(1,3-diphenyl-1H-pyrazol-5-yl)- (9CI) ; Propionamide, 2-(dimethylamino)-N-(1,3-diphenylpyrazol-5-yl)-
InChI: InChI=1/C20H22N4O/c1-15(23(2)3)20(25)21-19-14-18(16-10-6-4-7-11-16)22-24(19)17-12-8-5-9-13-17/h4-15H,1-3H3,(H,21,25)
CAS NO:20170-20-1
Molecular Formula:C20H22N4O
Molecular Weight :334.4149
Molecular Structure :
Index of Refraction: 1.604
Surface Tension: 42.6 dyne/cm
Density: 1.13 g/cm3
Flash Point: 282.6 °C
Enthalpy of Vaporization: 82.2 kJ/mol
Boiling Point: 543.6 °C at 760 mmHg
Vapour Pressure: 7.07E-12 mmHg at 25°C

Pasalin Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 1390mg/kg (1390mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 4, Pg. 467, 1973.
mouse LD50 oral 960mg/kg (960mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: TREMOR

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION		 Gifu Daigaku Igakubu Kiyo. Papers of the Gifu University School of Medicine. Vol. 20, Pg. 360, 1972.
mouse LD50 subcutaneous 15200mg/kg (15200mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 4, Pg. 467, 1973.
rat LD50 intraperitoneal 1480mg/kg (1480mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 4, Pg. 467, 1973.
rat LD50 oral 815mg/kg (815mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)

BEHAVIORAL: TREMOR

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION		 Gifu Daigaku Igakubu Kiyo. Papers of the Gifu University School of Medicine. Vol. 20, Pg. 360, 1972.
rat LD50 subcutaneous > 12819mg/kg (12819mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 4, Pg. 467, 1973.

Pasalin Safety Profile

Moderately toxic by intraperitoneal and ingestion routes. An analgesic and anti-inflammatory agent. When Pasalin (CAS NO.20170-20-1) is heated to decomposition, it emits toxic fumes of NOx.

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