IUPAC Name: S-(2-Diethylaminoethyl) N,N-diphenylcarbamothioate hydrochloride
Synonyms of Phencarbamide hydrochloride (CAS NO.58-13-9) : Carbamic acid, diphenylthio-, S-(2-(diethylamino)ethyl) ester, hydrochloride ; Diphenylamin-(beta-diaethylaminoaethyl)carbamidthioester ; Fencarbamide hydrochloride ; S-(2-(Diethylamino)ethyl) diphenylthiocarbamate hydrochloride
CAS NO: 58-13-9
Molecular Formula:C19H25ClN2OS
Molecular Weight :364.9326
Molecular Structure :
Flash Point: 221 °C
Enthalpy of Vaporization: 69.92 kJ/mol
Boiling Point: 441.8 °C at 760 mmHg
Vapour Pressure: 5.27E-08 mmHg at 25°C
Phencarbamide hydrochloride (CAS NO.58-13-9) is used as intermediate in organic synthesis.
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
dog | LD50 | intravenous | > 20mg/kg (20mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 155, Pg. 393, 1965. | |
mouse | LD50 | intravenous | 32mg/kg (32mg/kg) | AUTONOMIC NERVOUS SYSTEM: "SMOOTH MUSCLE RELAXANT (MECHANISM UNDEFINED, SPASMOLYTIC)" | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 151, Pg. 515, 1964. |
mouse | LD50 | subcutaneous | 103mg/kg (103mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 155, Pg. 393, 1965. | |
rabbit | LD50 | intravenous | > 20mg/kg (20mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 155, Pg. 393, 1965. | |
rat | LD50 | intravenous | 33mg/kg (33mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 155, Pg. 393, 1965. | |
rat | LD50 | oral | 410mg/kg (410mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 155, Pg. 393, 1965. | |
rat | LD50 | subcutaneous | 400mg/kg (400mg/kg) | Archives Internationales de Pharmacodynamie et de Therapie. Vol. 155, Pg. 393, 1965. |
Poison by subcutaneous and intravenous routes. Moderately toxic by ingestion. When Phencarbamide hydrochloride (CAS NO.58-13-9) is heated to decomposition, it emits toxic fumes of SOx, NOx, and HCl. See also CARBAMATES and ESTERS.
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