Product Name

  • Name

    ALPHA-BROMOISOBUTYRIC ACID

  • EINECS
  • CAS No. 55-52-7
  • Article Data17
  • CAS DataBase
  • Density 0.99g/cm3
  • Solubility
  • Melting Point 25°C
  • Formula C9H14 N2
  • Boiling Point 287.1°Cat760mmHg
  • Molecular Weight 150.224
  • Flash Point 148°C
  • Transport Information
  • Appearance
  • Safety Poison by ingestion, intraperitoneal, subcutaneous, and intravenous routes. Human systemic effects by an unspecified route: visual field effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
  • Risk Codes
  • Molecular Structure Molecular Structure of 55-52-7 (ALPHA-BROMOISOBUTYRIC ACID)
  • Hazard Symbols
  • Synonyms Hydrazine,(a-methylphenethyl)- (6CI,8CI);(1-Methyl-2-phenylethyl)hydrazine; (a-Methylphenethyl)hydrazine; (b-Phenylisopropyl)hydrazine;1-Phenyl-2-hydrazinopropane; 2-Hydrazino-1-phenylpropane; Catron; Dicatron;PIH; Pheniprazine; Phenizine
  • PSA 38.05000
  • LogP 2.17210

Pheniprazine Chemical Properties

Product Name: Pheniprazine
CAS Registry Number: 55-52-7
Synonyms: (alpha-Methylphenethyl)hydrazine ; 1-Phenyl-2-hydrazinopropane ; 2-Hydrazino-1-phenylpropane ; 2-Hydrazinopropylbenzene ; Catron ; Dicatron ; EINECS 200-236-6 ; Fenilisopropilidrazina ; Feniprazina ; Feniprazina [INN-Spanish] ; Feniprazyne ; Feniprazyne [Polish] ; P 1142 ; PIH ; Pheniprazine ; Pheniprazinum ; Pheniprazinum [INN-Latin] ; Phenizine ; UNII-37VKD7067M ; beta-Phenylisopropylhydrazine ; Hydrazine, (1-methyl-2-phenylethyl)- (9CI)
Hydrazine, (alpha-methylphenethyl)- 
IUPAC Name: 1-phenylpropan-2-ylhydrazine 
Molecular Weight: 150.22086 [g/mol]
Molecular Formula: C9H14N2
XLogP3: 1.3
H-Bond Donor: 2
H-Bond Acceptor: 2 
Surface Tension: 38.6 dyne/cm
Density: 0.99 g/cm3
Flash Point: 148 °C
Enthalpy of Vaporization: 52.63 kJ/mol
Boiling Point: 287.1 °C at 760 mmHg
Vapour Pressure: 0.00253 mmHg at 25°C
Following is the molecular structure of Pheniprazine (CAS NO.55-52-7) is:

Pheniprazine Uses

  Pheniprazine (CAS NO.55-52-7) was used as an antidepressant in the 1960s and it also used in the treatment of angina pectoris and schizophrenia. It has been largely discontinued due to toxicity concerns such as jaundice, amblyopia, and optic neuritis.

Pheniprazine Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LDLo intravenous 30mg/kg (30mg/kg) SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS

GASTROINTESTINAL: NAUSEA OR VOMITING		 Journal of Pharmacology and Experimental Therapeutics. Vol. 128, Pg. 7, 1960.
cat LDLo subcutaneous 30mg/kg (30mg/kg) SENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE

GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS

GASTROINTESTINAL: NAUSEA OR VOMITING		 Journal of Pharmacology and Experimental Therapeutics. Vol. 128, Pg. 7, 1960.
man TDLo unreported 117mg/kg/2.5Y (117mg/kg) SENSE ORGANS AND SPECIAL SENSES: VISUAL FIELD CHANGES: EYE

SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE		 British Medical Journal. Vol. 1, Pg. 331, 1963.
mouse LD50 intraperitoneal 48mg/kg (48mg/kg) BEHAVIORAL: ANTICONVULSANT Japanese Journal of Pharmacology. Vol. 13, Pg. 186, 1963.
mouse LD50 intravenous 12100ug/kg (12.1mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 12, Pg. 352, 1962.
mouse LD50 oral 121mg/kg (121mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 166, Pg. 449, 1967.
mouse LD50 subcutaneous 95mg/kg (95mg/kg)   Annals of the New York Academy of Sciences. Vol. 80, Pg. 568, 1959.
rat LD50 intraperitoneal 40mg/kg (40mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 353, 1972.
rat LD50 intravenous 44mg/kg (44mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 353, 1972.
rat LD50 oral 34mg/kg (34mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 353, 1972.
rat LD50 subcutaneous 45mg/kg (45mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 353, 1972.

Pheniprazine Safety Profile

Poison by ingestion, intraperitoneal, subcutaneous, and intravenous routes. Human systemic effects by an unspecified route: visual field effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.

Pheniprazine Specification

 Pheniprazine (CAS NO.55-52-7) is an irreversible and nonselective monoamine oxidase inhibitor (MAOI) of the hydrazine chemical class.

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