Product Name

  • Name

    Phenol Red sodium salt

  • EINECS 252-057-8
  • CAS No. 34487-61-1
  • Density 0.972 g/cm3
  • Solubility Soluble in water
  • Melting Point 285 °C (dec.)(lit.)
  • Formula C19H13NaO5S
  • Boiling Point 562.8oC at 760mmHg
  • Molecular Weight 376.365
  • Flash Point 294.2oC
  • Transport Information
  • Appearance red liquid or red/brown crystals
  • Safety 26-36-37/39-45-36/37/39-27
  • Risk Codes 36/37/38-34
  • Molecular Structure Molecular Structure of 34487-61-1 (Phenol Red sodium salt)
  • Hazard Symbols IrritantXi, CorrosiveC
  • Synonyms 2-[(4-hydroxyphenyl)-(4-oxo-1-cyclohexa-2,5-dienylidene)methyl]benzenesulfonate;Phenol,4,4'-(1,1-dioxido-3H-2,1-benzoxathiol- 3-ylidene)bis-,monosodium salt;Sodium hydrogen 4,4-(3H-2,1-benzoxathiol-3-ylidene)bisphenolate S,S-dioxide;Phenolsulfonephthalein sodium;Phenol red sodium;
  • PSA 95.04000
  • LogP 4.62760

Synthetic route

phenolsulphophthaleine sodium salt
34487-61-1

phenolsulphophthaleine sodium salt

2-(4,4'-dihydroxy-benzhydryl)-benzenesulfonic acid
172464-36-7

2-(4,4'-dihydroxy-benzhydryl)-benzenesulfonic acid

Conditions
ConditionsYield
With hydrogenchloride; sodium tetrahydroborate In ethanol at 25℃; for 48h;
phenolsulphophthaleine sodium salt
34487-61-1

phenolsulphophthaleine sodium salt

Bis(phenol) phenyl sulfonate
115481-73-7

Bis(phenol) phenyl sulfonate

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 1.) NaBH4, 2.) 5percent HCl / aq. ethanol / 48 h / 25 °C
2: 72 percent / 1.) RT, 4h, 2.) CH2Cl2, 1 h
3: PCl5 / 3 h / 60 - 65 °C / 0.1 Torr
4: 92 percent / Et3N / CH2Cl2 / 12 h / 25 °C
5: 93 percent / HCl conc. / methanol / 20 h / Ambient temperature
View Scheme
phenolsulphophthaleine sodium salt
34487-61-1

phenolsulphophthaleine sodium salt

bis(4.acetoxyphenyl)<2-(phenoxysulfonyl)phenyl>methane
115511-92-7

bis(4.acetoxyphenyl)<2-(phenoxysulfonyl)phenyl>methane

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 1.) NaBH4, 2.) 5percent HCl / aq. ethanol / 48 h / 25 °C
2: 72 percent / 1.) RT, 4h, 2.) CH2Cl2, 1 h
3: PCl5 / 3 h / 60 - 65 °C / 0.1 Torr
4: 92 percent / Et3N / CH2Cl2 / 12 h / 25 °C
View Scheme
phenolsulphophthaleine sodium salt
34487-61-1

phenolsulphophthaleine sodium salt

Acetic acid 4-[(4-acetoxy-phenyl)-(2-chlorosulfonyl-phenyl)-methyl]-phenyl ester
147510-56-3

Acetic acid 4-[(4-acetoxy-phenyl)-(2-chlorosulfonyl-phenyl)-methyl]-phenyl ester

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 1.) NaBH4, 2.) 5percent HCl / aq. ethanol / 48 h / 25 °C
2: 72 percent / 1.) RT, 4h, 2.) CH2Cl2, 1 h
3: PCl5 / 3 h / 60 - 65 °C / 0.1 Torr
View Scheme
phenolsulphophthaleine sodium salt
34487-61-1

phenolsulphophthaleine sodium salt

pyridinium 2-benzenesulfonate
115481-75-9

pyridinium 2-benzenesulfonate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 1.) NaBH4, 2.) 5percent HCl / aq. ethanol / 48 h / 25 °C
2: 72 percent / 1.) RT, 4h, 2.) CH2Cl2, 1 h
View Scheme
2-[2-[4-(dimethylamino)phenyl]ethenyl]-1-ethylquinolinium chloride
65201-92-5

2-[2-[4-(dimethylamino)phenyl]ethenyl]-1-ethylquinolinium chloride

phenolsulphophthaleine sodium salt
34487-61-1

phenolsulphophthaleine sodium salt

QR+*PR-

QR+*PR-

Conditions
ConditionsYield
In water
quinaldine blue
2768-90-3

quinaldine blue

phenolsulphophthaleine sodium salt
34487-61-1

phenolsulphophthaleine sodium salt

PNC+*PR-

PNC+*PR-

Conditions
ConditionsYield
In water
phenolsulphophthaleine sodium salt
34487-61-1

phenolsulphophthaleine sodium salt

3',3'',5',5''-tetrabromophenolsulphonephthalein sodium salt
62625-28-9

3',3'',5',5''-tetrabromophenolsulphonephthalein sodium salt

Conditions
ConditionsYield
With Agrocybe aegerita heme-thiolate peroxygenase; dihydrogen peroxide; sodium bromide at 20℃; pH=5; Reagent/catalyst; Enzymatic reaction;

Phenol red sodium salt Specification

The IUPAC name of Phenol red sodium salt is sodium 4-[3-(4-hydroxyphenyl)-1,1-dioxo-2,1λ6-benzoxathiol-3-yl]phenolate. With the CAS registry number 34487-61-1, it is also named as Phenol, 4,4'-(1,1-dioxido-3H-2,1-benzoxathiol-3-ylidene)bis-, sodium salt (1:1). The product's categories are analytical chemistry; indicator (pH); pH indicators. It is dark red crystals or powder which is soluble in water, and slightly soluble in alcohol. In addition, Phenol red sodium salt is stable and incompatible with strong oxidizing agents. And it acts as a pH indicator.

The other characteristics of this product can be summarized as: (1)#H bond acceptors: 5; (2)#H bond donors: 2; (3)#Freely Rotating Bonds: 4; (4)Rotatable Bond Count: 2; (5)Tautomer Count: 2; (6)Exact Mass: 376.038139; (7)MonoIsotopic Mass: 376.038139; (8)Topological Polar Surface Area: 95; (9)Heavy Atom Count: 26; (10)Complexity: 575; (11)Undefined Atom StereoCenter Count: 1; (12)Covalently-Bonded Unit Count: 2.

When you are using this chemical, please be cautious about it as the following:
It can causes burns. And it is irritating to eyes, respiratory system and skin. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. If you want to contact this product, you must wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 

People can use the following data to convert to the molecule structure.
1. SMILES: [Na+].[O-]c1ccc(cc1)C3(OS(=O)(=O)c2ccccc23)c4ccc([O-])cc4;
2. InChI: InChI=1/C19H14O5S.Na/c20-15-9-5-13(6-10-15)19(14-7-11-16(21)12-8-14)17-3-1-2-4-18(17)25(22,23)24-19;/h1-12,20-21H;/q;+1/p-2.

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