Pirimicarb

EPA Genetic Toxicology Program.

The Pirimicarb, with the CAS registry number 23103-98-2 and EINECS registry number 245-430-1, has the systematic name of 2-(dimethylamino)-5,6-dimethylpyrimidin-4-yl dimethylcarbamate. It is also called carbamic acid, N,N-dimethyl-, 2-(dimethylamino)-5,6-dimethyl-4-pyrimidinyl ester. And the molecular formula of this chemical is C₁₁H₁₈N₄O₂.

The physical properties of Pirimicarb are as following: (1)ACD/LogP: 1.70; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 1.68; (4)ACD/LogD (pH 7.4): 1.7; (5)ACD/BCF (pH 5.5): 11.11; (6)ACD/BCF (pH 7.4): 11.57; (7)ACD/KOC (pH 5.5): 192.74; (8)ACD/KOC (pH 7.4): 200.75; (9)#H bond acceptors: 6; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 3; (12)Polar Surface Area: 58.56 Å²; (13)Index of Refraction: 1.548; (14)Molar Refractivity: 66.09 cm³; (15)Molar Volume: 207.8 cm³; (16)Polarizability: 26.2×10^-24cm³; (17)Surface Tension: 45.5 dyne/cm; (18)Density: 1.146 g/cm³; (19)Flash Point: 179.6 °C; (20)Enthalpy of Vaporization: 62.07 kJ/mol; (21)Boiling Point: 373.4 °C at 760 mmHg; (22)Vapour Pressure: 8.99E-06 mmHg at 25°C.

Uses and preparation of Pirimicarb: It is a carbamate insecticide used to control aphids on vegetable, cereal and orchard crops by inhibiting acetylcholinesterase activity. This chemical can be prepared via the common systematic method of carbamate chemicals for agriculture.

You should be cautious while dealing with this chemical. It is a highly flammable chemcial which is harmful by inhalation, in contact with skin and if swallowed. It is toxic if swallowed, and irritates eyes. What's more, it is very toxic to aquatic organisms, and may cause long-term adverse effects in the aquatic environment. Therefore, you had better take the following instructions: Wear suitable protective clothing, and in case of contacting with eyes, rinse immediately with plenty of water and seek medical advice; Keep away from sources of ignition - No smoking; Do not breathe dust; This material and/or its container must be disposed of as hazardous waste; Avoid release to the environment. Refer to special instructions safety data sheet; In case of accident or if you feel unwell, seek medical advice immediately (show label where possible).

You can still convert the following datas into molecular structure:
(1)SMILES: O=C(Oc1nc(nc(c1C)C)N(C)C)N(C)C
(2)InChI: InChI=1/C11H18N4O2/c1-7-8(2)12-10(14(3)4)13-9(7)17-11(16)15(5)6/h1-6H3
(3)InChIKey: YFGYUFNIOHWBOB-UHFFFAOYAL

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
bird - wild	LD50	oral	30mg/kg (30mg/kg)		Journal of Agricultural and Food Chemistry. Vol. 24, Pg. 136, 1976.
chicken	LD50	oral	25mg/kg (25mg/kg)		"Pesticide Index," Frear, E.H., ed., State College, PA, College Science Pub., 1969Vol. 5, Pg. 184, 1976.
dog	LD50	oral	100mg/kg (100mg/kg)		"Pesticide Index," Frear, E.H., ed., State College, PA, College Science Pub., 1969Vol. 5, Pg. 184, 1976.
duck	LD50	oral	17200ug/kg (17.2mg/kg)		Pesticide Manual. Vol. 9, Pg. 690, 1991.
mouse	LD50	oral	68mg/kg (68mg/kg)		Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 45(4), Pg. 8, 1980.
pigeon	LD50	oral	20mg/kg (20mg/kg)		Journal of Agricultural and Food Chemistry. Vol. 24, Pg. 136, 1976.
quail	LD50	oral	54mg/kg (54mg/kg)		Journal of Agricultural and Food Chemistry. Vol. 29, Pg. 779, 1981.
rabbit	LDLo	skin	900mg/kg (900mg/kg)		Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 45(4), Pg. 8, 1980.
rat	LD50	oral	100mg/kg (100mg/kg)		Archives of Toxicology, Supplement. Vol. 4, Pg. 449, 1980.
rat	LD50	skin	> 500mg/kg (500mg/kg)		Special Publication of the Entomological Society of America. Vol. 78-1, Pg. 60, 1978.