Product Name: Plafibride (CAS NO.63394-05-8)
Molecular Formula: C16H22ClN3O4
Molecular Weight: 355.86g/mol
Mol File: 63394-05-8.mol
Einecs: 264-121-2
Density: 1.251 g/cm3
Surface Tension: 46.3 dyne/cm
XLogP3-AA: 2.4
H-Bond Donor: 2
H-Bond Acceptor: 5
Structure Descriptors of Plafibride (CAS NO.63394-05-8):
IUPAC Name: 2-(4-chlorophenoxy)-2-methyl-N-(morpholin-4-ylmethylcarbamoyl)propanamide
Canonical SMILES: CC(C)(C(=O)NC(=O)NCN1CCOCC1)OC2=CC=C(C=C2)Cl
InChI: InChI=1S/C16H22ClN3O4/c1-16(2,24-13-5-3-12(17)4-6-13)14(21)19-15(22)18-11-20-7-9-23-10-8-20/h3-6H,7-11H2,1-2H3,(H2,18,19,21,22)
InChIKey: DDDQVDIPBFGVIG-UHFFFAOYSA-N
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
guinea pig | LD50 | oral | 2168mg/kg (2168mg/kg) | Archivos de Farmacologia y Toxicologia. Vol. 4, Pg. 137, 1978. | |
hamster | LD50 | intraperitoneal | 880mg/kg (880mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 31, Pg. 1816, 1981. | |
hamster | LD50 | oral | > 4gm/kg (4000mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 31, Pg. 1816, 1981. | |
mouse | LD50 | intraperitoneal | 710mg/kg (710mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 31, Pg. 1816, 1981. | |
mouse | LD50 | intravenous | 126mg/kg (126mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 31, Pg. 1816, 1981. | |
mouse | LD50 | oral | 3365mg/kg (3365mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 31, Pg. 1816, 1981. | |
rat | LD50 | intraperitoneal | 975mg/kg (975mg/kg) | Archivos de Farmacologia y Toxicologia. Vol. 4, Pg. 137, 1978. | |
rat | LD50 | intravenous | 95mg/kg (95mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 31, Pg. 1816, 1981. | |
rat | LD50 | oral | > 4gm/kg (4000mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 31, Pg. 1816, 1981. |
Poison by intravenous route. Moderately toxic by ingestion and intraperitoneal routes. Experimental teratogenic and reproductive effects. Used as an antithrombotic agent. When heated to decomposition it emits very toxic fumes of Cl− and NOx.
Plafibride ,its CAS NO. is 63394-05-8,the synonyms is 1-(2-(p-Chlorophenoxy)-2-methylpropionyl)-3-(morpholinomethyl)urea ; BRN 0569805 ; EINECS 264-121-2 ; ITA-104 ; Idonor ; N'-Morpholinomethylurea, N-2-(p-chlorophenoxy)isobutyryl- ; N-2(p-Chlorophenoxy)-2-methylpropionyl-N'-morpholinomethylurea ; N-2(p-Chlorophenoxy)isobutyryl-N'-morpholinomethylurea ; Perifunal ; Plafibridum ; UNII-5J7C4JZ564 ; Propanamide, 2-(4-chlorophenoxy)-2-methyl-N-(((4-morpholinylmethyl)amino)carbonyl)- .
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View