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Name
delta(2-89)-tissue plasminogen activator
- EINECS
- CAS No. 105913-11-9
- Density
- Solubility
- Melting Point
- Formula
- Boiling Point
- Molecular Weight 0
- Flash Point
- Transport Information
- Appearance
- Safety A poison by subcutaneous and intravenous routes. Experimental reproductive effects. When heated to decomposition it emits acrid smoke and irritating vapors.
- Risk Codes
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Molecular Structure
- Hazard Symbols
- Synonyms Angiokinase;GMK 527; K 2P; Plasminogen activator PLA; Pleurokinase; Tisokinase
- PSA 0.00000
- LogP 0.00000
Plasminogen activator Chemical Properties
Product Name: Plasminogen activator
Synonyms of Plasminogen activator (CAS NO.105913-11-9): delta(2-89)-Tissue plasminogen activator ; AK-124 ; Angiokinase ; CCRIS 3520 ; GMK 527 ; Recombinant tissue-type plasminogen activator ; Tisokinase ; rt-PA ; Plasminogen activator ak-124
CAS NO: 105913-11-9
Classification Code: Reproductive Effect Mol File: 105913-11-9.mol
Plasminogen activator Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| monkey | LD50 | intravenous | > 3300ku/kg (3300000iu/kg) | Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 33, Pg. 998, 1991. | |
| mouse | LD50 | intravenous | 51800ug/kg (51.8mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 16(Suppl, |
| mouse | LD50 | subcutaneous | > 100mg/kg (100mg/kg) | SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) SKIN AND APPENDAGES (SKIN): HAIR: OTHER | Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 16(Suppl, |
| rat | LD50 | intravenous | 30400ug/kg (30.4mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD CARDIAC: OTHER CHANGES LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 16(Suppl, |
| rat | LD50 | subcutaneous | > 60mg/kg (60mg/kg) | SKIN AND APPENDAGES (SKIN): HAIR: OTHER | Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 16(Suppl, |
Plasminogen activator Safety Profile
A poison by subcutaneous and intravenous routes. Experimental reproductive effects. When heated to decomposition it emits acrid smoke and irritating vapors.
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