Product Name

  • Name

    propyl 4-diethylcarbamoylmethoxy-3-methoxyphenylacetate

  • EINECS
  • CAS No. 1421-14-3
  • Article Data2
  • CAS DataBase
  • Density 1.087g/cm3
  • Solubility
  • Melting Point
  • Formula C18H27 N O5
  • Boiling Point 459.7°Cat760mmHg
  • Molecular Weight 337.416
  • Flash Point 231.8°C
  • Transport Information
  • Appearance
  • Safety Poison by intravenous route. Moderately toxic by ingestion. An experimental teratogen. Experimental reproductive effects. Human systemic effects by intravenous route: general anesthesia. When heated to decomposition it emits toxic fumes of NOx. Used as an anesthetic.
  • Risk Codes
  • Molecular Structure Molecular Structure of 1421-14-3 (propyl 4-diethylcarbamoylmethoxy-3-methoxyphenylacetate)
  • Hazard Symbols
  • Synonyms Aceticacid, [4-[(diethylcarbamoyl)methoxy]-3-methoxyphenyl]-, propyl ester (7CI,8CI);13245RP; 2180TH; BAY 1420; Epontol; FBA 1420; Fabantol; Fabontal; Propanidid;Propanidide; Propantan; Propyl4-(N,N-diethylcarbamidomethoxy)-3-methoxy-phenylacetate; Propyl[4-[(diethylcarbamoyl)methoxy]-3-methoxyphenyl]acetate; Sombrevin; TH 2180; WH5668; [4-[(Diethylcarbamoyl)methoxy]-3-methoxyphenyl]acetic acid propyl ester
  • PSA 65.07000
  • LogP 2.43810

Propanidide Chemical Properties

IUPAC Name: Propyl 2-[4-[2-(diethylamino)-2-oxoethoxy]-3-methoxyphenyl]acetate
Synonyms of Propanidide (CAS NO.1421-14-3) : [3-Methoxy-4-[(N,N-diethylcarbamido)methoxy]phenyl]acetic Acid n-Propyl Ester ; [4-[(Diethylcarbamoyl)methoxy]-3-methoxyphenyl]acetic Acid Propyl Ester ; 4-[2-(Diethylamino)-2-oxoethoxy]-3-methoxybenzeneacetic Acid Propyl Ester ; Benzeneacetic acid, 4-(2-(diethylamino)-2-oxoethoxy)-3-methoxy-, propyl ester ; Propyl [4-[(Diethylcarbamoyl)methoxy]-3-methoxyphenyl]acetate ; Propyl {4-[2-(diethylamino)-2-oxoethoxy]-3-methoxyphenyl}acetate
InChI:InChI=1/C18H27NO5/c1-5-10-23-18(21)12-14-8-9-15(16(11-14)22-4)24-13-17(20)19(6-2)7-3/h8-9,11H,5-7,10,12-13H2,1-4H3
CAS NO:1421-14-3
Molecular Formula:C18H27NO5                   
Molecular Weight :337.4107                                    
Molecular Structure :
EINECS: 215-822-7
Index of Refraction: 1.503  
Surface Tension: 38.1 dyne/cm 
Density: 1.087 g/cm3 
Flash Point: 231.8 °C 
Enthalpy of Vaporization: 72.02 kJ/mol 
Boiling Point: 459.7 °C at 760 mmHg 
Vapour Pressure: 1.24E-08 mmHg at 25°C 

Propanidide Uses

 Propanidide (CAS NO.1421-14-3) is ultrashort intravenous anesthetics.

Propanidide Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LD50 intravenous 80mg/kg (80mg/kg)   Acta Anaesthesiologica Scandinavica, Supplementum. Vol. 17, Pg. 21, 1965.
dog LD50 intravenous 80mg/kg (80mg/kg)   Acta Anaesthesiologica Scandinavica, Supplementum. Vol. 17, Pg. 21, 1965.
human TDLo intravenous 5mg/kg (5mg/kg) BEHAVIORAL: GENERAL ANESTHETIC British Journal of Anesthesia. Vol. 45, Pg. 1097, 1973.
mouse LD50 intravenous 113mg/kg (113mg/kg)   Oyo Yakuri. Pharmacometrics. Vol. 19, Pg. 845, 1980.
rabbit LD50 intravenous 75mg/kg (75mg/kg)   Acta Anaesthesiologica Scandinavica, Supplementum. Vol. 17, Pg. 21, 1965.
rat LD50 intravenous 81mg/kg (81mg/kg)   Acta Anaesthesiologica Scandinavica, Supplementum. Vol. 17, Pg. 21, 1965.
rat LD50 oral > 10gm/kg (10000mg/kg)   Toxicology and Applied Pharmacology. Vol. 18, Pg. 185, 1971.

Propanidide Safety Profile

Poison by intravenous route. Moderately toxic by ingestion. An experimental teratogen. Experimental reproductive effects. Human systemic effects by intravenous route: general anesthesia. When Propanidide (CAS NO.1421-14-3) is heated to decomposition, it emits toxic fumes of NOx.

Related Products

Hot Products

Post buying leads

About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

©2008 LookChem.com,License: ICP

NO.:Zhejiang16009103

complaints:service@lookchem.com Desktop View