Product Name

  • Name

    1-[10-[3-(dimethylamino)propyl]-10H-phenothiazin-2-yl]propan-1-one maleate

  • EINECS
  • CAS No. 25333-83-9
  • Density
  • Solubility
  • Melting Point
  • Formula C20H24N2OS•C4H4O4
  • Boiling Point 507.4°C at 760 mmHg
  • Molecular Weight 456.60
  • Flash Point 260.7°C
  • Transport Information
  • Appearance
  • Safety Poison by ingestion and intraperitoneal routes. When heated to decomposition it emits very toxic fumes of NOx and SOx.
  • Risk Codes
  • Molecular Structure Molecular Structure of 25333-83-9 (1-[10-[3-(dimethylamino)propyl]-10H-phenothiazin-2-yl]propan-1-one maleate)
  • Hazard Symbols
  • Synonyms 1678 CB;Propiopromazine maleate;PROPIOPROMAZINE;
  • PSA 123.45000
  • LogP 4.61050

Propiopromazine maleate Chemical Properties

Molecule structure of Propiopromazine maleate (CAS NO.25333-83-9):

IUPAC Name: (Z)-But-2-enedioic acid; 1-[10-[3-(dimethylamino)propyl]phenothiazin-2-yl]propan-1-one 
Molecular Weight: 456.55452 g/mol
Molecular Formula: C24H28N2O5
Boiling Point: 507.4 °C at 760 mmHg
Flash Point: 260.7 °C
Enthalpy of Vaporization: 77.75 kJ/mol
Vapour Pressure: 2.04E-10 mmHg at 25 °C 
H-Bond Donor: 2
H-Bond Acceptor: 7
Rotatable Bond Count: 8
Tautomer Count: 2
Exact Mass: 456.171893
MonoIsotopic Mass: 456.171893
Topological Polar Surface Area: 98.2
Heavy Atom Count: 32
Complexity: 547
Canonical SMILES: CCC(=O)C1=CC2=C(C=C1)SC3=CC=CC=C3N2CCCN(C)C.C(=CC(=O)O)C(=O)O
Isomeric SMILES: CCC(=O)C1=CC2=C(C=C1)SC3=CC=CC=C3N2CCCN(C)C.C(=C\C(=O)O)\C(=O)O
InChI: InChI=1S/C20H24N2OS.C4H4O4/c1-4-18(23)15-10-11-20-17(14-15)22(13-7-12-21(2)3)16-8-5-6-9-19(16)24-20;5-3(6)1-2-4(7)8/h5-6,8-11,14H,4,7,12-13H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
InChIKey: BBYDPETWONYPJS-BTJKTKAUSA-N
EINECS of Propiopromazine maleate (CAS NO.25333-83-9): 246-861-8

Propiopromazine maleate Toxicity Data With Reference

1.    

orl-mus LD50:650 mg/kg

    27ZQAG    Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,44.
2.    

ipr-mus LD50:170 mg/kg

    27ZQAG    Psychotropic Drugs and Related Compounds E. Usdin andD.H. Efron,2nd ed.,Washington, DC.: 1972,44.
3.    

orl-bwd LD50:316 mg/kg

    AECTCV    Archives of Environmental Contamination and Toxicology. 12 (1983),355.

Propiopromazine maleate Safety Profile

Poison by ingestion and intraperitoneal routes. When heated to decomposition it emits very toxic fumes of NOx and SOx.

Propiopromazine maleate Specification

 Propiopromazine maleate (CAS NO.25333-83-9) is also named as 1-(10-(3-(Dimethylamino)propyl)-10H-phenothiazin-2-yl)-1-propanone (Z)-2-butenedioate (1:1) ; 1-(10-(3-(Dimethylamino)propyl)phenothiazin-2-yl)-1-propanone maleate ; 1-Propanone, 1-(10-(3-dimethylaminopropyl)phenothiazin-2-yl)-, maleate (6CI) ; 1678 CB ; NSC 169500 ; Propiolpromazine ; Propionylpromazine maleate ; 1-(10-(3-(Dimethylamino)propyl)-10H-phenothiazin-2-yl)propan-1-onemaleate ; 1-Propanone, 1-(10-(3-(dimethylamino)propyl)-10H-phenothiazin-2-yl)-, maleate ; 1-Propanone, 1-(10-(3-(dimethylamino)propyl)-2-phenothiazinyl)-, maleate (1:1) (7CI,8CI) .

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