The Pyruvate kinase, with the CAS registry number 9001-59-6, is also known as Kinase (phosphorylating), pyruvate. Its EINECS number is 232-616-2. Its EC number is 2.7.1.40. Its classification code is TSCA Flag XU [Exempt from reporting under the Inventory Update Rule]. Its storage temperature is 2-8°C. This chemical is an enzyme involved in glycolysis. It catalyzes the transfer of a phosphate group from phosphoenolpyruvate (PEP) to ADP, yielding one molecule of pyruvate and one molecule of ATP. Genetic defects of this enzyme cause the disease known as pyruvate kinase deficiency. In this condition, a lack of pyruvate kinase slows down the process of glycolysis. Pyruvate kinase also serves as a regulatory enzyme for gluconeogenesis, a biochemical pathway in which the liver generates glucose from pyruvate and other substrates.
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