Product Name

Stability

    Stable, but darkens slowly in light. Incompatible withstrong oxidizing agents.

Toxicology

    Harmful if swallowed. May be harmful if inhaled.

    Toxicity data

  • Melting Point 238 C
  • Formula C35H42 N2 O9
  • Boiling Point 756.8°C at 760 mmHg
  • Molecular Weight 634.726
  • Flash Point 411.5°C
  • Transport Information
  • Appearance white to cream powder
  • Safety Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion and subcutaneous routes. Human systemic effects by ingestion: olfactory changes, somnolence, and antipsychotic effects. Experimental reproductive effects. When heated to decomposition it emits toxic NOx.
  • Risk Codes 25-20/21/22
  • Molecular Structure Molecular Structure of 24815-24-5 (RESCINNAMINE)
  • Hazard Symbols Xn
  • Synonyms 3b,20a-Yohimban-16b-carboxylic acid, 18b-hydroxy-11,17a-dimethoxy-, methyl ester, 3,4,5-trimethoxycinnamate(ester) (8CI); Rescinnamine (6CI); Yohimban-16-carboxylic acid,11,17-dimethoxy-18-[[(2E)-1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl]oxy]-,methyl ester, (3b,16b,17a,18b,20a)- (9CI);Benz[g]indolo[2,3-a]quinolizine, yohimban-16-carboxylic acid deriv.;3,4,5-Trimethoxycinnamoyl methyl reserpate; Anaprel; Apoterin; Apoterin S;Cartric; Cinnaloid; Methyl trimethoxycinnamoylreserpate; Moderil; NSC 15628;O-(3,4,5-Trimethoxy-trans-cinnamoyl) methyl reserpate; Rescinnamin; Rescisan;Resealoid; Reserpic acid methyl ester 3,4,5-trimethoxycinnamate; Reserpinine;Reserpinine (C35 alkaloid); Scinnamina
  • PSA 117.78000
  • LogP 4.50860

Rescinnamine Chemical Properties

The Synonyms name of Rescinnamine (CAS NO.24815-24-5): 11,17alpha-Dimethoxy-18beta-((1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl)oxy)-3beta,20alpha-yohimban-16beta-carboxylic acid methyl ester ; 3,4,5-Trimethoxycinnamic acid, methyl reserpate ; 3,4,5-Trimethoxycinnamoyl methyl reserpate ; 3,4,5-Trimethylcinnamic acid, ester with methyl reserpate ; 3,4,5-Trimethylcinnamoyl methyl reserpate ; 3beta,20alpha-Yohimban-16beta-carboxylic acid, 18beta-Hydroxy-11,17alpha-dimethoxy-, methyl ester, 3,4,5-
trimethoxycinnamate (ester), (E)- ; 4-25-00-01323 (Beilstein Handbook Reference) ; AI3-52763 ; Anaprel ; Apolon ; Apoterin ; BRN 0075328 ; CCRIS 4711 ; Cartric ; Cinamine ; Cinatabs ; Cinnaloid ; Cinnasil ; HSDB 2176 ; Methyl 18-O-(3,4,5-trimethoxycinnamoyl)reserpate ;Methyl ; 1alpha,2beta,3alpha,4,4aalpha,5,7,8,13,13bbeta,14,14aalpha-dodecahydro-2alpha,11-dimethoxy-3beta-(3,4,5-trimethoxycinnamoyloxy)benz(g)indolo(2,3-a)quinolizine-1beta-carboxylate ; Methyl reserpate 3,4,5-trimethoxycinnamic acid ester ; Methyl trimethoxycinnamoylreserpate ; Moderil ; NSC 15628 ; Normorescina ; Paresinan ; Raupyrol ; Raurescin ;Raurescine ; Recinnamine ; Recitensina ; Rescaloid ; Rescamin ; Rescidan ; Rescin ; Rescinamina ; Rescinnaminum [INN-Latin] ; Rescinpal ; Scinnamina ; Tenamine ; Trimethoxy cinnamoyl reserpate de methyl ; Trimethoxy cinnamoyl reserpate de methyl [French] ; Trimethoxycinnamoyl methyl reserpate ; Tuareg ; Yohimban-16-carboxylic acid, 11,17-dimethoxy-18-((1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl)-oxy)-, methyl ester,(3beta,16beta,17alpha,18beta(E),20alpha
CAS: 24815-24-5
EINECS: 246-471-8 
Molecular Formula: C35H42N2O9
Formula Weight: 634.72 g/mol
Molecular Structure:

Index of Refraction: 1.621 
Density: 1.31 g/cm3 
Flash Point: 411.5 °C 
Boiling Point: 756.8 °C at 760 mmHg 
Chemical Properties: white to cream powder
General Description: Odorless white to cream colored crystalline powder.
Air & Water: Reactions Insoluble in water.
 

Rescinnamine Toxicity Data With Reference

The toxicity of Rescinnamine (CAS NO.24815-24-5):

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LDLo intravenous 35mg/kg (35mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 23, Pg. 600, 1973.
human TDLo oral 4ug/kg/D (0.004mg/kg) SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: ANTIPSYCHOTIC		 "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 517, 1969.
mouse LD50 intraperitoneal 65mg/kg (65mg/kg)   French Medicament Patent Document. Vol. #5226M,
mouse LD50 intravenous 56mg/kg (56mg/kg)   U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#00965,
mouse LD50 oral 1420mg/kg (1420mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 109, 1972.
mouse LD50 subcutaneous 263mg/kg (263mg/kg)   French Medicament Patent Document. Vol. #5226M,
rat LD50 intraperitoneal 250mg/kg (250mg/kg)   Drugs in Japan Vol. 6, Pg. 898, 1982.
rat LD50 oral 1gm/kg (1000mg/kg)   Drugs in Japan Vol. 6, Pg. 898, 1982.
rat LD50 subcutaneous 540mg/kg (540mg/kg)   Drugs in Japan Vol. 6, Pg. 898, 1982.

Rescinnamine Safety Profile

The Risk Statements of Rescinnamine (CAS NO.24815-24-5):R25 :Toxic if swallowed.
Safety Statements: S22:Do not breathe dust. S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
RIDADR: 1544
HazardClass: 6.1(b)
PackingGroup: III
Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion and subcutaneous routes. Human systemic effects by ingestion: olfactory changes, somnolence, and antipsychotic effects. Experimental reproductive effects. When heated to decomposition it emits toxic NOx.

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