Product Name

  • Name

    RITANSERIN

  • EINECS
  • CAS No. 87051-43-2
  • Density 1.3g/cm3
  • Solubility
  • Melting Point 145.5°
  • Formula C27H25 F2 N3 O S
  • Boiling Point 618.7°C at 760 mmHg
  • Molecular Weight 477.578
  • Flash Point 328°C
  • Transport Information
  • Appearance
  • Safety A poison by intraperitoneal route. When heated to decomposition it emits toxic vapors of NOx, F, and SOx.
  • Risk Codes R36/37/38   
  • Molecular Structure Molecular Structure of 87051-43-2 (RITANSERIN)
  • Hazard Symbols
  • Synonyms Ritanserin;Tiserton
  • PSA 65.85000
  • LogP 5.42090

Ritanserin Chemical Properties

IUPAC Name: 6-[2-[4-[bis(4-Fluorophenyl)methylene]-1-piperidyl]ethyl]-7-methyl-thiazolo[2,3-b]pyrimidin-5-one
Synonyms: 5H-Thiazolo[3,2-a]pyrimidin-5-one, 6-[2-[4-[bis(4-fluorophenyl)methylene]-1-piperidinyl]ethyl]-7-methyl- ; 6-(2-{4-[bis(4-Fluorophenyl)methylidene]piperidin-1-yl}ethyl)-7-methyl-5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one ; (Ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methylene]-piperidin-1-yl}-ethyl)-7-methyl-thiazolo[3,2-a]pyrimidin-5-one ; 4-[2-[4-[bis(4-Fluorophenyl)methylidene]-1-piperidyl]ethyl]-3-methyl-9-thia-2,6-diazabicyclo[4.3.0]nona-1,3,7-trien-5-one
Product Categories: API;Serotonin receptor
Molecular Structure of Ritanserin (CAS NO.87051-43-2) :
Molecular Formula of Ritanserin (CAS NO.87051-43-2) : C27H25F2N3OS
Molecular Weight of Ritanserin (CAS NO.87051-43-2) : 477.57
CAS NO: 87051-43-2
Index of Refraction: 1.646
Surface Tension: 46.4 dyne/cm
Density: 1.3 g/cm3
Flash Point: 328 °C
Enthalpy of Vaporization: 91.72 kJ/mol
Boiling Point: 618.7 °C at 760 mmHg
Vapour Pressure: 3.11E-15 mmHg at 25°C
Solubility : methanol: >10 mg/mL
Appearance: white solid

Ritanserin Uses

1.Ritanserin is a serotonin antagonist with wide-reaching possibilities for the treatment of many neurological disorders.
2.When used together with typical antipsychotics in the treatment of schizophrenia is able to decrease negative symptoms and adds some "atypicality" as parkinsonism is slightly decreased.
3.Possible effects on platelets have also been proposed.

Ritanserin Toxicity Data With Reference

1.    

ipr-rat TDLo:5 mg/kg

    BIPBU*    Biological & pharmaceutical bulletin. 24 (2001),1431.

Ritanserin Safety Profile

A poison by intraperitoneal route. When heated to decomposition it emits toxic vapors of NOx, F, and SOx.
Hazard Codes IrritantXi
Risk Statements 36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements 22-26-36
S22:Do not breathe dust. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36:Wear suitable protective clothing.
WGK Germany 3

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