Product Name

  • Name

    ZORUBICIN HCL

  • EINECS
  • CAS No. 36508-71-1
  • Density 1.54g/cm3
  • Solubility
  • Melting Point
  • Formula C34H35 N3 O10 . Cl H
  • Boiling Point °Cat760mmHg
  • Molecular Weight 682.127
  • Flash Point °C
  • Transport Information
  • Appearance
  • Safety Poison by intraperitoneal route. Human systemic effects by intravenous route: cardiovascular, blood, and gastrointestinal system effects. Human mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and HCl. Used as an antineoplastic agent. See also RUBIDAZONE.
  • Risk Codes
  • Molecular Structure Molecular Structure of 36508-71-1 (ZORUBICIN HCL)
  • Hazard Symbols
  • Synonyms Benzoicacid, [1-[(2S,4S)-4-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenyl]ethylidene]hydrazide,monohydrochloride (9CI); Benzoic acid, [1-[4-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenyl]ethylidene]hydrazide,monohydrochloride, (2S-cis)-; NSC 164011; RP 22050 hydrochloride; Rubidazonehydrochloride; Zorubicin hydrochloride
  • PSA 210.23000
  • LogP 4.13900

Rubidazone monohydrochloride Chemical Properties

IUPAC Name: N-[1-[(2S,4S)-4-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyl-tetrahydropyran-2-yl]oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]ethylideneamino]benzamide hydrochloride
Synonyms: Rubidazone monohydrochloride ; N'-[(1E)-1-{(2S,4S)-4-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-2-yl}ethylidene]benzohydrazide hydrochloride ; Zorubicin ; Zorubicin hydrochloride
CAS NO: 36508-71-1
Molecular Formula of Rubidazone monohydrochloride (36508-71-1) : C34H36ClN3O10
Molecular Weight  of Rubidazone monohydrochloride (36508-71-1) : 682.12
Molecular Structure  of Rubidazone monohydrochloride (36508-71-1) :
EINECS: 253-076-4
Flash Point: 481.7 °C
Enthalpy of Vaporization: 132.91 kJ/mol
Boiling Point: 872.9 °C at 760 mmHg
Vapour Pressure: 1.44E-32 mmHg at 25°C

Rubidazone monohydrochloride Toxicity Data With Reference

1.    

mmo-sat 20 µg/plate

     EJCAAH    European Journal of Cancer. 19 (1983),641.
2.    

mma-sat 4 µg/plate

     EJCAAH    European Journal of Cancer. 19 (1983),641.
3.    

pic-esc 700 µg/L

     MUREAV    Mutation Research. 77 (1980),197.
4.    

oms-hmn:lym 1 mg/L

     EJCAAH    European Journal of Cancer. 14 (1978),741.
5.    

ivn-hmn TDLo:48 mg/kg/21D-I:CVS,GIT,BLD

     CTRRDO    Cancer Treatment Reports. 62 (1978),1053.
6.    

ipr-mus LD50:28,710 µg/kg

     NCISP*    National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program, Bethesda, MD 20205 JAN86 .

Rubidazone monohydrochloride Safety Profile

Poison by intraperitoneal route. Human systemic effects by intravenous route: cardiovascular, blood, and gastrointestinal system effects. Human mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and HCl. Used as an antineoplastic agent. See also RUBIDAZONE.

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