SB 239063

IUPAC Name: trans-4-(4-Fluorophenyl)-1-(4-hydroxycyclohexyl)-5-(2-methoxypyrimidin-4-yl)imidazole
Molecular Formula: C₂₀H₂₁FN₄O₂
Molecular Weight: 368.41
Freely Rotating Bonds: 5
Polar Surface Area: 73.06 Å²
Index of Refraction: 1.655
Molar Refractivity: 99.56 cm³
Molar Volume: 271.1 cm³
Polarizability: 39.47 ×10^-24 cm³
Surface Tension: 49.2 dyne/cm
Density: 1.35 g/cm³
Flash Point: 313.5 °C
Enthalpy of Vaporization: 93.22 kJ/mol
Boiling Point: 594.8 °C at 760 mmHg
Vapour Pressure: 5.42E-15 mmHg at 25°C 
The Cas Register Number of  trans-1-(4-Hydroxycyclohexyl)-4-(4-fluorophenyl)-5-(2-methoxypy-rimidin-4-yl)imidazole is 193551-21-2.The chemical synonyms of trans-1-(4-Hydroxycyclohexyl)-4-(4-fluorophenyl)-5-(2-methoxypy-rimidin-4-yl)imidazole (CAS NO.193551-21-2) are cyclohexanol, 4-[4-(4-fluorophenyl)-5-(2-methoxy-4-pyrimidinyl)-1H-imidazol-1-yl]-, trans- ; trans-4-[4-(4-Fluorophenyl)-5-(2-methoxypyrimidin-4-yl)-1H-imidazol-1-yl]cyclohexanol ; 193551-21-2 [RN] ; 4-[4-(4-Fluoro-phenyl)-5-(2-methoxy-pyrimidin-4-yl)-imidazol-1-yl]-cyclohexanol ; trans -1-(4-Hydroxycyclohexyl)-4-(4-fluorophenyl)-5-(2-methoxypyrimidin-4-yl)imidazole  and  trans-4-[4-(4-Fluorophenyl)-5-(2-methoxy-4-pyrimidinyl)-1H-imidazol-1-yl]cyclohexanol . The molecular structure of trans-1-(4-Hydroxycyclohexyl)-4-(4-fluorophenyl)-5-(2-methoxypy-rimidin-4-yl)imidazole (CAS NO.193551-21-2) is.

 trans-1-(4-Hydroxycyclohexyl)-4-(4-fluorophenyl)-5-(2-methoxypy-rimidin-4-yl)imidazole (CAS NO.193551-21-2) is used as pharmaceutical intermediate.

 
The condensation of p- fluorobenzaldehyde (I) with p-toluenesulfinic acid (II) in the presence of camphorsulfonic acid in formamide produced the tosylmethyl formamide (III). This was dehydrated to the required isocyanide (IV) using POCl3 and Et3N in cold dimethoxyethane

A poison by ingestion. When heated to decomposition it emits toxic vapors of NO_x and F⁻.
Safety Statements: 22-24/25 
S22: Do not breathe dust. 
S24/25: Avoid contact with skin and eyes.
WGK Germany: 3
RTECS: GV9458000