Sodium L-pyroglutamate supplier

Name
Sodium L-pyroglutamate
EINECS 249-277-1
CAS No. 28874-51-3
Article Data3
CAS DataBase
Density 1.45
Solubility 613g/L at 20℃
Melting Point 125 °C
Formula C₅H₆NNaO₃
Boiling Point 453.1 °C at 760 mmHg
Molecular Weight 151.097
Flash Point 227.8 °C
Transport Information
Appearance Pale yellow transparent liquid
Safety
Risk Codes
Molecular Structure
Hazard Symbols
Synonyms L-Proline,5-oxo-, monosodium salt (9CI);Proline, 5-oxo-, monosodium salt, L- (8CI);2-Pyrrolidinone-5-carboxylic acid sodium salt;2-Pyrrolidone-5-carboxylic acidsodium salt;5-Carboxy-2-pyrrolidone sodium salt;Ajidew N 50;Ajidew NL 50;PDSI 101;Sodium 2-oxo-5-pyrrolidinecarboxylate;Sodium2-pyrrolidinone-5-carboxylate;Sodium 2-pyrrolidone-5-carboxylate;Sodium L-pyrrolidonecarboxylate;Sodium pidolate;Sodium pyroglutamate;
PSA 69.23000
LogP -1.65630

Synthetic route

: 142-47-2
monosodium glutamate

: 28874-51-3
sodium L-pyroglutamate

Conditions

Conditions	Yield
In water at 180℃; for 2h;

: 142-47-2, 149-65-5, 15383-53-6, 16079-50-8, 16177-21-2, 16690-92-9, 21932-17-2, 26247-79-0, 28223-73-6, 30617-64-2, 30811-79-1, 32221-81-1, 32342-59-9, 56-86-0
glutamic acid sodium salt

: 28874-51-3
sodium L-pyroglutamate

Conditions

Conditions	Yield
In water at 180℃; for 2h;	n/a

: 28874-51-3
sodium L-pyroglutamate

: zinc pidolate

Conditions

Conditions	Yield
With nitric acid; zinc(II) sulfate In water at 20℃; for 0.5h; pH=3.7 - 5.2;

: 28874-51-3
sodium L-pyroglutamate

: 123-56-8
Succinimide

Conditions

Conditions	Yield
With ammonium peroxydisulfate; silver nitrate In water at 20℃; for 2h;

Sodium L-pyroglutamate Specification

The IUPAC name of Sodium L-pyroglutamate is sodium (2S)-5-oxopyrrolidine-2-carboxylate. With the CAS registry number 28874-51-3, it is also named as 2-Pyrrolidone-5-carboxylic acid sodium salt. The product's other registry numbers are 2494-03-3; 52497-17-3; 53935-45-8. Besides, this chemical is pale yellow transparent liquid which is a cyclized derivative of L-Glutamic acid. In addition, its molecular formula is C₅H₆NNaO₃ and its molecular weight is 151.09.

The other characteristics of Sodium L-pyroglutamate can be summarized as: (1)EINECS: 249-277-1; (2)ACD/LogP: -2.39; (3)# of Rule of 5 Violations: 0; (4)ACD/LogD (pH 5.5): -4.43; (5)ACD/LogD (pH 7.4): -5.92; (6)ACD/BCF (pH 5.5): 1; (7)ACD/BCF (pH 7.4): 1; (8)ACD/KOC (pH 5.5): 1; (9)ACD/KOC (pH 7.4): 1; (10)H bond acceptors: 4; (11)H bond donors: 2; (12)Freely Rotating Bonds: 1; (13)Polar Surface Area: 57.61 Å²; (14)Density: 1.45 g/cm³; (15)Flash Point: 227.8 °C; (16)Melting point: 125 °C; (17)Enthalpy of Vaporization: 78.09 kJ/mol; (18)Boiling Point: 453.1 °C at 760 mmHg; (19)Vapour Pressure: 1.79E-09 mmHg at 25 °C.

People can use the following data to convert to the molecule structure.
(1)SMILES:[Na+].[O-]C(=O)[C@H]1NC(=O)CC1
(2)InChI:InChI=1/C5H7NO3.Na/c7-4-2-1-3(6-4)5(8)9;/h3H,1-2H2,(H,6,7)(H,8,9);/q;+1/p-1/t3-;/m0./s1
(3)InChIKey:CRPCXAMJWCDHFM-SYBSRVMOBU
(4)Std. InChI:InChI=1S/C5H7NO3.Na/c7-4-2-1-3(6-4)5(8)9;/h3H,1-2H2,(H,6,7)(H,8,9);/q;+1/p-1/t3-;/m0./s1
(5)Std. InChIKey:CRPCXAMJWCDHFM-DFWYDOINSA-M

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	oral	10400mg/kg (10400mg/kg)		International Journal of Toxicology. Vol. 18(Suppl,

Product Name

Sodium L-pyroglutamate

Synthetic route

Sodium L-pyroglutamate Specification

Related Products

Hot Products