Product Name

  • Name

    Sodium risedronate

  • EINECS 1806241-263-5
  • CAS No. 115436-72-1
  • Density
  • Solubility
  • Melting Point 252-262°C
  • Formula C7H10NNaO7P2
  • Boiling Point 692.3 °C at 760 mmHg
  • Molecular Weight 350.13
  • Flash Point 372.5 °C
  • Transport Information
  • Appearance fine white to off-white crystalline powder
  • Safety 20-22-36/37
  • Risk Codes 62-64
  • Molecular Structure Molecular Structure of 115436-72-1 (Sodium risedronate)
  • Hazard Symbols
  • Synonyms Risedronic acid [INN];Acidum risedronicum [INN-Latin];Acido risedronico [INN-Spanish];(1-Hydroxy-2-(3-pyridyl)ethylidene)diphosphonic acid;Actonel;NE-58095;RischorriteRisedronate sodium;Actonel (TN);Acide risedronique [INN-French];Risedronate sodium (USAN);Monosodium (1-hydroxy-2-(3-pyridinyl)ethylidene)bisphosphonate;Phosphonic acid, (1-hydroxy-2-(3-pyridinyl)ethylidene)bis-;Phosphonic acid,[1-hydroxy-2-(3-pyridinyl)- ethylidene]bis-,monosodium salt;Residronate sodium;RisedronateSodium;Risedronate Sodium;NE 58095;
  • PSA 170.63000
  • LogP 0.06380

Sodium risedronate Chemical Properties

Molecular Structure:

Molecular Formula: C7H10NNaO7P2
Molecular Weight: 305.0941
IUPAC Name: Sodium hydroxy-(1-hydroxy-1-phosphono-2-pyridin-3-ylethyl)phosphinate 
CAS NO: 115436-72-1
Classification Code: Drug / Therapeutic Agent ; Human Data ; Regulator [calcium]
H bond acceptors: 8
H bond donors: 5
Freely Rotating Bonds: 5
Polar Surface Area: 123.8 Å2
Flash Point: 372.5 °C
Enthalpy of Vaporization: 106.53 kJ/mol
Boiling Point: 692.3 °C at 760 mmHg
Vapour Pressure: 4.03E-20 mmHg at 25 °C
Product Categories: Active Pharmaceutical Ingredients; Bone Resorption Inhibitor; All Inhibitors; Osteoporosis; Inhibitors; Intermediates & Fine Chemicals; Pharmaceuticals; Phosphorylating and Phosphitylating Agents
Appearance of Sodium risedronate (CAS NO.115436-72-1): Fine White to Off-White Crystalline Powder

Sodium risedronate Uses

  Sodium risedronate (CAS NO.115436-72-1) can be used for the total synthesis of osteoporosis drugs.

Sodium risedronate Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
women TDLo oral 1800ug/kg/3D- (1.8mg/kg) SENSE ORGANS AND SPECIAL SENSES: IRITIS: EYE Lancet. Vol. 341, Pg. 436, 1993.

Sodium risedronate Safety Profile

Human systemic effects. When heated to decomposition it emits toxic vapors of NOx and POx.

Sodium risedronate Specification

 Synonyms of Sodium risedronate (CAS NO.115436-72-1) are Risedronate sodium [USAN] ; Actonel ; Monosodium (1-hydroxy-2-(3-pyridinyl)ethylidene)bisphosphonate ; NE 58095 ; Risedronate sodium ; Sodium trihydrogen (1-hydroxy-2-(3-pyridyl)ethylidene)diphosphonate ; UNII-OFG5EXG60L ; Phosphonic acid, (1-hydroxy-2-(3-pyridinyl)ethylidene)bis-, monosodium salt .

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