Sodium sarcosinate supplier

Name
Sodium sarcosinate
EINECS 224-338-5
CAS No. 4316-73-8
Article Data5
CAS DataBase
Density 1.2 g/cm³
Solubility
Melting Point > 0oC
Formula C₃H₆NNaO₂
Boiling Point 195.1 °C at 760 mmHg
Molecular Weight 111.076
Flash Point 71.8 °C
Transport Information
Appearance clear liquid
Safety
Risk Codes R36/37/38
Molecular Structure
Hazard Symbols
Synonyms Sarcosine, monosodium salt (8CI);Sarcosinesodium salt;Sodium (methylamino)acetate;Sodium N-(methylamino)acetate;Sodium N-methylglycinate;Glycine,N-methyl-, monosodium salt (9CI);
PSA 52.16000
LogP -1.65340

Synthetic route

: 109-83-1
(2-hydroxyethyl)(methyl)amine

: 4316-73-8
sodium sarcosinate

Conditions

Conditions	Yield
With sodium hydroxide; Cu/Ni Raney catalyst In water at 160℃; under 7500.75 Torr; for 4h;	97.2%
With (6-di-tert-butylphosphinomethyl-2,2’-bipyridyl)Ru(CO)HCl; water; sodium hydroxide In 1,4-dioxane for 24h; Schlenk technique; Inert atmosphere; Glovebox; Reflux;	> 99 %Spectr.

: 107-97-1
sarcosine

: 4316-73-8
sodium sarcosinate

Conditions

Conditions	Yield
With ammonia; sodium

: 5616-32-0
(methylamino)acetonitrile

: 4316-73-8
sodium sarcosinate

Conditions

Conditions	Yield
With sodium hydroxide at 75℃; for 4h; Temperature; Large scale;

: 3926-62-3
sodium monochloroacetic acid

: 74-89-5
methylamine

: 4316-73-8
sodium sarcosinate

Conditions

Conditions	Yield
at 10 - 200℃; under 836.056 - 228015 Torr; Flow reactor;

: 2767-80-8
tris(hydroxymethyl)phosphine

: 4316-73-8
sodium sarcosinate

: tris(N-methyl-N-sodiumcarboxylatomethylaminomethyl)phosphine

Conditions

Conditions	Yield
In water at 20℃; for 1h; Condensation;	99%

: 4316-73-8
sodium sarcosinate

: 79-11-8
chloroacetic acid

: 71160-37-7
sodium methyliminodiacetate

Conditions

Conditions	Yield
Stage #1: sodium sarcosinate; chloroacetic acid With sodium iodide In water at 20℃; for 1h; Large scale; Stage #2: With sodium hydroxide In water at 55 - 90℃; for 4.5h; pH=8.5 - 9; Large scale;	98%

: 4316-73-8
sodium sarcosinate

: oleic acid chloride

: 110-25-8
N-oleoylsarcosine

Conditions

Conditions	Yield
With water; sodium hydroxide In toluene at 30℃; for 1h; Solvent;	97.8%

2M-NaOH: 2M-NaOH

: 107-97-1
sarcosine

: 617-09-4
di-o-tolyl carbonate

: 4316-73-8
sodium sarcosinate

: 116714-27-3
N-methoxycarbonyl-N-methyl-glycine

Conditions

Conditions	Yield
With hydrogenchloride	90.5%

...Expand

: 156-62-7
calcium cyanamide

: 4316-73-8
sodium sarcosinate

: 57-00-1
Creatinine

Conditions

Conditions	Yield
With phosphoric acid; sulfuric acid	86%
phosphoric acid	75%
sulfuric acid

: 7703-74-4
2,6-bis-(bromomethyl)pyridine

: 4316-73-8
sodium sarcosinate

: 146448-83-1
N,N'-<(pyridine-2,6-diyl)bis(methylene)>bis

Conditions

Conditions	Yield
With sodium hydroxide In methanol for 13h; Heating;	85%

: 32315-10-9
bis(trichloromethyl) carbonate

: 4316-73-8
sodium sarcosinate

: 5840-76-6
sarcosine-N-carboxyanhydride

Conditions

Conditions	Yield
With 4-methyl-morpholine In water; acetonitrile at 20℃; Flow reactor;	81%

: 4316-73-8
sodium sarcosinate

: 171179-03-6
4-[(3-bromophenyl)-amino]-6-fluoropyrido[3,4-d]pyrimidine

: {[4-(3-Bromo-phenylamino)-pyrido[3,4-d]pyrimidin-6-yl]-methyl-amino}-acetic acid

Conditions

Conditions	Yield
In ethanol at 95℃; for 48h;	79%

: 420-04-2
CYANAMID

: 4316-73-8
sodium sarcosinate

: 57-00-1
Creatinine

Conditions

Conditions	Yield
Stage #1: sodium sarcosinate With hydrogenchloride In water pH=9.6; Cooling; Stage #2: CYANAMID In water at 75 - 80℃; for 3.5h;	76.2%
In 2-Methyl-1,2-propanediol	75%
With carbon dioxide In water at 75℃; for 6h; pH=9 - 10;	75%
With formic acid In tert-butyl methyl ether at 50℃; for 1h; pH=9.8;	70%
With ammonium chloride	68%

: 88-88-0
2,4,6-trinitrochlorobenzene

: 4316-73-8
sodium sarcosinate

: 124052-31-9
N-methyl-N-(2,4,6-trinitrophenyl)glycine

Conditions

Conditions	Yield
In methanol; water for 0.333333h;	70%

: Boc-Ser(Bn)-OH

: 4316-73-8
sodium sarcosinate

: Boc-L-Ser(O-Bn)-Sar-OH

Conditions

Conditions	Yield
Stage #1: Boc-Ser(Bn)-OH With 4-methyl-morpholine; N-ethyl-N,N-diisopropylamine; isobutyl chloroformate In acetonitrile at 20℃; for 0.00138889h; Flow reactor; Stage #2: sodium sarcosinate In water; acetonitrile at 20℃; for 0.00277778h; Flow reactor;	67%

: 4316-73-8
sodium sarcosinate

: 822-39-9
2-chloro-1,3,2-dioxaphospholan

: 63972-72-5
9-methyl-1,4,6-trioxa-9-aza-5λ5-phospha-spiro[4.4]nonan-7-one

: 4316-73-8
sodium sarcosinate

: 75-56-9, 16033-71-9
methyloxirane

: 18484-89-4
2-oxo-4,6-dimethyl-morpholine

Conditions

Conditions	Yield
In water

: 112-16-3
n-dodecanoyl chloride

: 4316-73-8
sodium sarcosinate

: 97-78-9
N-acyl sarcosinate

Conditions

Conditions	Yield
In water at 40 - 50℃; for 1h; pH 9.5-10.5;
With hydrogenchloride In hexane; water at 5 - 15℃; for 6h; pH=11 - 11.5; Temperature; pH-value;	586 g

: 17746-05-3
undecanoyl chloride

: 4316-73-8
sodium sarcosinate

: 36461-64-0
N-methyl-N-undecanoyl-glycine

Conditions

Conditions	Yield
In water at 40 - 50℃; for 1h; pH 9.5-10.5;

: 17746-06-4
n-tridecanoyl chloride

: 4316-73-8
sodium sarcosinate

: 83871-14-1
N-methyl-N-tridecanoyl-glycine

Conditions

Conditions	Yield
In water at 40 - 50℃; for 1h; pH 9.5-10.5;

: 40480-10-2
heptadecanoyl chloride

: 4316-73-8
sodium sarcosinate

: 83871-15-2
N-heptadecanoyl-N-methyl-glycine

Conditions

Conditions	Yield
In water at 40 - 50℃; for 1h; pH 9.5-10.5;

: 4316-73-8
sodium sarcosinate

: 112-13-0
n-decanoyl chloride

: 2671-91-2
N-decanoyl sarcosine

Conditions

Conditions	Yield
In water at 40 - 50℃; for 1h; pH 9.5-10.5;

: 4316-73-8
sodium sarcosinate

: 112-64-1
tetradecanoyl chloride

: 52558-73-3, 2421-31-0
N-tetradecanoylsarcosine

Conditions

Conditions	Yield
In water at 40 - 50℃; for 1h; pH 9.5-10.5;

: 4316-73-8
sodium sarcosinate

: 112-76-5
Stearoyl chloride

: 142-48-3
N-stearoyl sarcosine

Conditions

Conditions	Yield
In water at 40 - 50℃; for 1h; pH 9.5-10.5;

: 4316-73-8
sodium sarcosinate

: 112-67-4
n-hexadecanoyl chloride

: 2421-33-2
N-hexadecanoylsarcosine

Conditions

Conditions	Yield
In water at 40 - 50℃; for 1h; pH 9.5-10.5;
With sodium hydroxide at 45℃; for 1h;

: 38460-95-6
undec-10-enoyl chloride

: 4316-73-8
sodium sarcosinate

: N-undecylenoyl sarcosine

Conditions

Conditions	Yield
With hydrogenchloride; sodium hydroxide for 0.5h; Ambient temperature;

: 20907-32-8
sodium allyloxide

: 4316-73-8
sodium sarcosinate

N-methyl-N-<3-hydroxy-propyl>-glycine methyl ester: N-methyl-N-<3-hydroxy-propyl>-glycine methyl ester

Conditions

Conditions	Yield
at 108℃; und Veresterung des Reaktionsprodukts mit methanol.HCl;

: 107-97-1
sarcosine

: 112-80-1
cis-Octadecenoic acid

: 4316-73-8
sodium sarcosinate

: 110-25-8
N-oleoylsarcosine

Conditions

Conditions	Yield
In water; isopropyl alcohol

...Expand

: 2855-19-8
Decyl-oxiran

: 4316-73-8
sodium sarcosinate

: 67-63-0
isopropyl alcohol

A: C15H32O2

B: C15H30NO3(1-)*Na(1+)

C: 1119-87-5
dodecane-1,2-diol

Conditions

Conditions	Yield
at 70 - 82℃; for 5.5h;

...Expand

: 420-04-2
CYANAMID

: 4316-73-8
sodium sarcosinate

: 6020-87-7
creatine monohydrate powder

Conditions

Conditions	Yield
In water
With water at 20 - 80℃; for 1h; Temperature; Large scale;

: 59044-32-5, 7459-29-2
erucic acid chloride

: 4316-73-8
sodium sarcosinate

: 133152-18-8
C25H47NO3

Conditions

Conditions	Yield
With sodium hydroxide In water at 30 - 35℃; for 1h; pH=9 - 11;

: 112-16-3
n-dodecanoyl chloride

: 4316-73-8
sodium sarcosinate

: 137-16-6
sodium N-lauroylsarcosinate

Conditions

Conditions	Yield
In water at 10 - 30℃; for 5h; pH=10.3 - 10.6; Schotten-Baumann Reaction; Inert atmosphere;
With sodium hydroxide In water at 10 - 30℃; for 5h; pH=10.3 - 10.6; Inert atmosphere;

Sodium sarcosinate Specification

The Sodium sarcosinate, with the CAS registry number 4316-73-8, is also known as N-Methylglycine monosodium salt. Its EINECS registry number is 224-338-5. This chemical's molecular formula is C₃H₆NNaO₂ and molecular weight is 111.08. What's more, its IUPAC name is called Sodium 2-(methylamino)acetic acid. It should be stored in a cool, dry and well-ventilated place. This chemical can be prepared by formaldehyde, hydrocyanic acid and methylamine.

Physical properties about Sodium sarcosinate are: (1)ACD/LogP: -0.793; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -3.29; (4)ACD/LogD (pH 7.4): -3.29; (5)ACD/BCF (pH 5.5): 1.00; (6)ACD/BCF (pH 7.4): 1.00; (7)ACD/KOC (pH 5.5): 1.00; (8)ACD/KOC (pH 7.4): 1.00; (9)#H bond acceptors: 3; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 2; (12)Polar Surface Area: 40.54 Å²; (13)Flash Point: 71.8 °C; (14)Enthalpy of Vaporization: 47.54 kJ/mol; (15)Boiling Point: 195.1 °C at 760 mmHg; (16)Vapour Pressure: 0.184 mmHg at 25 °C.

Uses of Sodium sarcosinate: (1) it is used as cosurfactant, dyeing auxiliary and biochemical reagent; (2) it is used to produce other chemicals. For example, it can react with 2-chloro-1,3,5-trinitro-benzene to get N-methyl-N-(2,4,6-trinitrophenyl)glycine. The reaction occurs with solvents methanol and H₂O. The reaction time is 20 min. The yield is 70 %.

Sodium sarcosinate can react with 2-chloro-1,3,5-trinitro-benzene to get N-methyl-N-(2,4,6-trinitrophenyl)glycine.

You can still convert the following datas into molecular structure:
(1) SMILES: [Na+].[O-]C(=O)CNC
(2) InChI: InChI=1S/C3H7NO2.Na/c1-4-2-3(5)6;/h4H,2H2,1H3,(H,5,6);/q;+1/p-1
(3) InChIKey: ZUFONQSOSYEWCN-UHFFFAOYSA-M

Product Name

Sodium sarcosinate

Synthetic route

Sodium sarcosinate Specification

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