Product Name

  • Name

    8-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-thia-4,8-diazaspiro[4.5]decan-3-one hydrochloride (1:1)

  • EINECS
  • CAS No. 27007-85-8
  • Density 1.42g/cm3
  • Solubility
  • Melting Point
  • Formula C22H24 Cl N3 O S2 . Cl H
  • Boiling Point 695.3°Cat760mmHg
  • Molecular Weight 482.52
  • Flash Point 374.3°C
  • Transport Information
  • Appearance
  • Safety Moderately toxic by ingestion and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of SOx, NOx, and Cl−.
  • Risk Codes
  • Molecular Structure Molecular Structure of 27007-85-8 (8-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-thia-4,8-diazaspiro[4.5]decan-3-one hydrochloride (1:1))
  • Hazard Symbols
  • Synonyms 1-Thia-4,8-diazaspiro[4.5]decan-3-one,8-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-, monohydrochloride (9CI);1-Thia-4,8-diazaspiro[4.5]decan-3-one,8-[3-(2-chlorophenothiazin-10-yl)propyl]-, monohydrochloride (8CI);8-[3-(2-Chloro-10-phenothiazinyl)propyl]-3-oxo-1-thia-4,8-diazaspiro[4,5]decanemonohydrochloride; APY 606; Clospirazine hydrochloride; Diceplon; Disperon
  • PSA
  • LogP

Spiclomazine hydrochloride Chemical Properties

IUPAC  Name: 8-[3-(2-Chlorophenothiazin-10-yl)propyl]-1-thia-4,8-diazaspiro[4.5]decan-3-one hydrochloride 
Molecular Formula: C22H24ClN3OS2•ClH
Molecular Weight: 482.52
Freely Rotating Bonds: 4
Polar Surface Area: 77.39 Å2
Flash Point: 374.3 °C
Enthalpy of Vaporization: 101.84 kJ/mol
Boiling Point: 695.3 °C at 760 mmHg
Vapour Pressure: 3.51E-19 mmHg at 25°C
 The Cas Register Number of Spiclomazine hydrochloride is 27007-85-8.The chemical synonyms of Spiclomazine hydrochloride (CAS NO.27007-85-8) are 1-Thia-4,8-diazaspiro[4.5]decan-3-one, 8-[3- (2-chlorophenothiazin-10-yl)propyl]-, monohydrochloride ; 8-(3-(2-Chlorophenothiazin-10-yl)propyl)-1-thia-4,8-diazaspiro(4.5)decan-3-one hydrochloride ; Clospirazine hydrochloride ; Spiclomazine and Spiclomazine hydrochloride .The molecular structure of Spiclomazine hydrochloride (CAS NO.27007-85-8) is.

Spiclomazine hydrochloride Uses

 Spiclomazine hydrochloride (CAS NO.27007-85-8) is used in organic synthesis.

Spiclomazine hydrochloride Toxicity Data With Reference

1.    

orl-rat LD50:3800 mg/kg

     OYYAA2    Oyo Yakuri. Pharmacometrics. 4 (1970),487.
2.    

ipr-rat LD50:2950 mg/kg

     OYYAA2    Oyo Yakuri. Pharmacometrics. 4 (1970),487.
3.    

orl-mus LD50:3800 mg/kg

     OYYAA2    Oyo Yakuri. Pharmacometrics. 4 (1970),487.
4.    

ipr-mus LD50:3200 mg/kg

     OYYAA2    Oyo Yakuri. Pharmacometrics. 4 (1970),487.

Spiclomazine hydrochloride Safety Profile

Moderately toxic by ingestion and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of SOx, NOx, and Cl−.

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