STREPTOKINASE

EINECS: 232-647-1
Storage temp: -20 °C
Sensitive: Hygroscopic
Appearance: White or off-white amorphous powder
Solubility: Soluble in water and saline
Product categories of Streptokinase (CAS NO.9002-01-1): Enzymes;Biochemical products;Therapeutic enzyme

 Streptokinase (CAS NO.9002-01-1) has been used as an inexpensive and effective clot-dissolving medication in some cases of myocardial infarction (heart attack) and pulmonary embolism. It may find a use in helping to prevent postoperative adhesions, a common complication of surgery, especially abdominal surgery (appendectomy, gall stones, hysterectomy, etc.)

Moderately toxic by intravenous route. Human systemic effects by subcutaneous or intravenous routes: effects on the nose, dyspnea and unspecified allergic affects. A thrombolytic agent used to dissolve blood clots in vivo.
 

Hazard Codes: BXi
Risk Statements: 36/37/38
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 22-24/25-36-26
S22:Do not breathe dust. 
S24/25:Avoid contact with skin and eyes. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36:Wear suitable protective clothing.

 Streptokinase ,its cas register number is 9002-01-1. It also can be called SK .It is very unstable in dilute solution and can bind and activate human plasminogen. There are three domains to Streptokinase , denoted β (residues 151–287), α (residues 1–150), and γ (residues 288–414). Each domain binds plasminogen, although none can activate plasminogen independently. One study using animal models (rats) found that when used with a PHBV membrane drug-delivery system, it was 90 percent effective in preventing adhesions. Streptokinase (CAS NO.9002-01-1) is given intravenously as soon as possible after the onset of a heart attack to dissolve clots in the arteries of the heart wall and it is usually given only for a person's first heart attack.