Molecular structure of Succinylsulfathiazole (CAS NO.116-43-8) is:
Product Name: Succinylsulfathiazole
CAS Registry Number: 116-43-8
IUPAC Name: 4-Oxo-4-[4-(1,3-thiazol-2-ylsulfamoyl)anilino]butanoic acid
Molecular Weight: 355.38942 [g/mol]
Molecular Formula: C13H13N3O5S2
XLogP3: -0.7
H-Bond Donor: 3
H-Bond Acceptor: 7
EINECS: 204-141-0
Index of Refraction: 1.679
Molar Refractivity: 83.8 cm3
Molar Volume: 221.9 cm3
Surface Tension: 88 dyne/cm
Density: 1.601 g/cm3
Product Categories: Antibiotics for Research and Experimental Use;Biochemistry;Sulfonamides (Antibiotics for Research and Experimental Use);Antibacterial;Antibiotics;Antibiotics A to;Antibiotics N-SAntibiotics;Chemical Structure Class;Inhibits an EnzymeAntibiotics;Interferes with DNA SynthesisSpectrum of Activity;L - ZAntibiotics;Mechanism of Action;Sulfonamides
Canonical SMILES: C1=CC(=CC=C1NC(=O)CCC(=O)O)S(=O)(=O)NC2=NC=CS2
InChI: InChI=1S/C13H13N3O5S2/c17-11(5-6-12(18)19)15-9-1-3-10(4-2-9)23(20,21)16-13-14-7-8-22-13/h1-4,7-8H,5-6H2,(H,14,16)(H,15,17)(H,18,19)
InChIKey: SKVLYVHULOWXTD-UHFFFAOYSA-N
Succinylsulfathiazole (CAS NO.116-43-8) can be used as sulfonamid class antibiotic.
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 5700mg/kg (5700mg/kg) | Journal of Pharmacology and Experimental Therapeutics. Vol. 75, Pg. 231, 1942. | |
mouse | LD50 | intravenous | 10gm/kg (10000mg/kg) | "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980Vol. 7, Pg. 151, 1981. |
Safty information about Succinylsulfathiazole (CAS NO.116-43-8) is:
Hazard Codes: Xn
Risk Statements: 42/43
R42/43:May cause sensitization by inhalation and skin contact.
Safety Statements: 22-36/37-45
S22:Do not breathe dust.
S36/37:Wear suitable protective clothing and gloves.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: 3249
WGK Germany: 3
RTECS: WM4767000
HazardClass: 6.1(b)
PackingGroup: III
Succinylsulfathiazole , its cas register number is 116-43-8. It also can be called 2-(N(4)-Succinylsulfanilamido)thiazole; p-2-Thiazolylsulfamoylsuccinanilic acid; 4'-(2-Thiazolylsulfamoyl)succinanilic acid ; Colistatin ; Cremosuxidine ; Kaoxidin ; Rolsul .It is a sulfonamide.
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