• Name

  SULFORHODAMINE B

• EINECS 222-529-8
• CAS No. 3520-42-1
• Article Data5
• CAS DataBase
• Density 1.472[at 20℃]
• Solubility methanol: 1 mg/mL
• Melting Point
• Formula C₂₇H₂₉N₂O₇S₂^.Na
• Boiling Point
• Molecular Weight 580.658
• Flash Point
• Transport Information
• Appearance Deep red powder
• Safety 22-24/25
• Risk Codes 36/37/38
• Molecular Structure
• Hazard Symbols Xi
• Synonyms Ammonium,[6-(diethylamino)-9-(2,4-disulfophenyl)-3H-xanthen-3-ylidene]diethyl-,hydroxide, inner salt, sodium salt (8CI);C.I. Acid Red 52 (6CI);Xanthylium,3,6-bis(diethylamino)-9-(2,4-disulfophenyl)-, hydroxide, inner salt, sodiumsalt;Xanthylium, 3,6-bis(diethylamino)-9-(2,4-disulfophenyl)-, inner salt,sodium salt (9CI);Acid Leather Red KB;Acid Red 52;Acid Red B-SF;Acid Rhodamine B;Acid Rose B;Amacid Rhodamine B;Amido Rhodamine B;Brilliant Superlan Rhodamine 2B;Brilliant Superlan Rhodamine B;C.I. 45100;Colocid Rhodamine B;Conacid Red EB;Covasol Red W 4002;Daiwa IJ Red 207H;DinacidRhodamine B;Duasyn Acid Rhodamine B 01;Dyacid Red 4B;Dycosacid Rhodamine B;Food Color Red No.106;Food Red 106;Food Red No. 106;Hispacid Brilliant Pink B;Japan Red 106;Japan Red No. 106;Kayacyl Rhodamine FB;Kayaku Acid Rhodamine BH;Kiton Red 620;Kiton Red S;Kiton Rhodamine B;Kyton Red;Libacid Rhodamine LB;Lissamine Rhodamine B;Nylosan Rhodamine B;Pacid Rhodamine B;Phloxinerhodamine;Pro-Jet Red OAM;Rakuto Acid Rhodamine;Ravi Acid Rhodamine B;Red 106;Sandolan Rhodamine E-B400;Simacid Red 23011;Solar Rhodamine B;Sulfacid Brilliant Pink 3B;SulfacidBrilliant Pink 3B 1150;Sulforhodamin B;Vibra Color Red ARE 52;Vicoacid Red 52Y;Xylene Red B;
• PSA 150.78000
• LogP 7.81310

Synthetic route

3520-42-1

sulforhodamine B

62796-29-6

rhodamine B sulfonyl chloride

Conditions

Conditions	Yield
With oxalyl dichloride; N,N-dimethyl-formamide In dichloromethane at 20℃; for 16h;	88%
With oxalyl dichloride
With oxalyl dichloride In dichloromethane; N,N-dimethyl-formamide at 0 - 20℃; for 3.5h;
With oxalyl dichloride; N,N-dimethyl-formamide In dichloromethane at 20℃; for 22h; Inert atmosphere;

87156-40-9

1-amino-2-azidoethane

3520-42-1

sulforhodamine B

C29H34N6O6S2

Conditions

Conditions	Yield
With triethylamine In N,N-dimethyl-formamide at 20℃; Darkness;	76%

3520-42-1

sulforhodamine B

1232233-19-0

rhodamine 6G

C28H30N2O3*C27H30N2O7S2

Conditions

Conditions	Yield
In methanol for 2h;	50%

258864-54-9

trihexyl(tetradecyl)phosphonium chloride

3520-42-1

sulforhodamine B

N-[6-(diethylamino)-9-(2,4-disulfophenyl)-3H-xanthen-3-ylidene]-N-ethyl-ethanaminium hydroxide inner salt trihexyltetradecylphosphonium salt

Conditions

Conditions	Yield
In methanol; dichloromethane for 24h;

3520-42-1

sulforhodamine B

C47H65N5O14S2

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: oxalyl dichloride 2: triethylamine 3: hydrogenchloride / water View Scheme

3520-42-1

sulforhodamine B

Reaxys ID: 32620162

Reaxys ID: 32620162

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: oxalyl dichloride / dichloromethane; N,N-dimethyl-formamide / 3.5 h / 0 - 20 °C View Scheme

1100-88-5

benzyltriphenylphosphonium chloride

3520-42-1

sulforhodamine B

C27H29N2O7S2(1-)*C25H22P(1+)

Conditions

Conditions	Yield
In water at 20 - 85℃; for 1h;	5.93 g

3520-42-1

sulforhodamine B

14937-45-2

cetyltributylphosphonium bromide

C27H29N2O7S2(1-)*C28H60P(1+)

Conditions

Conditions	Yield
In water at 20 - 85℃; for 1h;	6.1 g

14187-32-7

dibenzo-18-crown-6

3520-42-1

sulforhodamine B

[(dibenzo-18-crown-6)(Na)(sulforhodamine B)]

Conditions

Conditions	Yield
In dichloromethane

3520-42-1

sulforhodamine B

2C27H29N2O7S2(1-)*Ca(2+)

Conditions

Conditions	Yield
With calcium chloride In water at 20 - 30℃; for 1h;
With calcium chloride In water at 20 - 30℃; for 1h;

3520-42-1

sulforhodamine B

2C27H29N2O7S2(1-)*Ba(2+)

Conditions

Conditions	Yield
With barium(II) chloride In water at 20 - 30℃; for 1h;

3520-42-1

sulforhodamine B

C27H29N2O7S2(1-)*H(1+)

Conditions

Conditions	Yield
With hydrogenchloride In water at 20 - 30℃; for 1h;

3520-42-1

sulforhodamine B

18-amino-8,11,13-abietatriene

C27H29N2O7S2(1-)*C20H31N*H(1+)

Conditions

Conditions	Yield
With acetic acid In water at 20 - 25℃; for 1.5h;

3520-42-1

sulforhodamine B

1092380-66-9

5-(N-(3-azidopropyl)sulfamoyl)-2-(6-(diethylamino)-3-(diethyliminio)-3H-xanthen-9-yl)benzenesulfonate

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 22 h / 20 °C / Inert atmosphere 2: dmap; N-ethyl-N,N-diisopropylamine / dichloromethane / 22 h / 20 °C View Scheme

Sulforhodamine B Specification