Product Name

  • Name

    TRIPROLIDINE HYDROCHLORIDE

  • EINECS 208-985-0
  • CAS No. 550-70-9
  • Article Data2
  • CAS DataBase
  • Density 1.061g/cm3
  • Solubility
  • Melting Point 116-118 °C
  • Formula C19H22 N2 . Cl H
  • Boiling Point 435.4°Cat760mmHg
  • Molecular Weight 314.858
  • Flash Point 217.1°C
  • Transport Information
  • Appearance
  • Safety Poison by subcutaneous and intravenous routes. Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of NOx and HCl.
  • Risk Codes 22-36/37/38
  • Molecular Structure Molecular Structure of 550-70-9 (TRIPROLIDINE HYDROCHLORIDE)
  • Hazard Symbols Xn
  • Synonyms Pyridine,2-[(1E)-1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl]-, monohydrochloride(9CI); Pyridine, 2-[1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl]-,monohydrochloride, (E)-; Pyridine, 2-[3-(1-pyrrolidinyl)-1-p-tolylpropenyl]-,monohydrochloride, (E)- (8CI); 295C51; Actidil; Actidilat; Actidilon; Entra; Pro-Actidil;Pro-Entra; Triprolidine hydrochloride; Venen;trans-1-(4-Methylphenyl)-1-(2-pyridyl)-3-pyrrolidinoprop-1-ene hydrochloride;trans-2-[3-(1-Pyrrolidinyl)-1-(p-tolyl)propenyl]pyridine hydrochloride
  • PSA 16.13000
  • LogP 4.65740

TRIPROLIDINE HYDROCHLORIDE Chemical Properties

Product Name: Triprolidine hydrochloride (CAS NO.550-70-9)


Molecular Formula: C19H23ClN2
Molecular Weight: 314.85g/mol
Mol File: 550-70-9.mol
Einecs: 208-985-0
Boiling point: 462 °C at 760 mmHg
Storage Temperature: 2-8°C
Flash Point: 233.2 °C
Density: 1.061g/cm3
Water Solubility: 500 mg/mL (20 °C)
Enthalpy of Vaporization: 73.68 kJ/mol
Vapour Pressure: 6.16E-09 mmHg at 25°C
H-Bond Donor: 1
H-Bond Acceptor: 2

TRIPROLIDINE HYDROCHLORIDE Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD intravenous > 5mg/kg (5mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: EXCITEMENT

LUNGS, THORAX, OR RESPIRATION: DYSPNEA		 British Journal of Pharmacology and Chemotherapy. Vol. 8, Pg. 171, 1953.
mouse LD50 intravenous 21mg/kg (21mg/kg)   British Journal of Pharmacology and Chemotherapy. Vol. 8, Pg. 171, 1953.
mouse LD50 oral 495mg/kg (495mg/kg)   Drugs in Japan Vol. 6, Pg. 525, 1982.
mouse LD50 subcutaneous 247mg/kg (247mg/kg)   Drugs in Japan Vol. 6, Pg. 525, 1982.
rat LD50 oral 840mg/kg (840mg/kg)   Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 22, Pg. 375, 1980.

TRIPROLIDINE HYDROCHLORIDE Safety Profile

Poison by subcutaneous and intravenous routes. Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of NOx and HCl.
Safety Information of Triprolidine hydrochloride (CAS NO.550-70-9):
Hazard Codes: Xn
Risk Statements: 22-36/37/38 
22:  Harmful if swallowed
36:  Irritating to the eyes 
37:  Irritating to the respiratory system 
38:  Irritating to the skin 
Safety Statements: 26-36
26:  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36:  Wear suitable protective clothing

TRIPROLIDINE HYDROCHLORIDE Specification

 Triprolidine hydrochloride ,its CAS NO. is 550-70-9,the synonyms is Trans-2[3-(1-pyrrolidinyl)-1-p-tolylpropenyl]pyridine hydrochloride ; Triprolidine hcl;trans-triprolidine hydrochloride ; (e)-2-[1-(4-Methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl]pyridine hydrochloride ; 2-[(1e)-1-(4-Methylphenyl)-3-pyrrolizino-1-propenyl]pyridine•hydrochloride ; Venen .

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