Product Name

  • Name

    Talisomycin

  • EINECS
  • CAS No. 65057-90-1
  • Density 1.58g/cm3
  • Solubility
  • Melting Point
  • Formula C68H110 N22 O27 S2
  • Boiling Point
  • Molecular Weight 1732.12
  • Flash Point
  • Transport Information
  • Appearance
  • Safety Poison by intraperitoneal, subcutaneous and intravenous routes. Human mutation data reported. When heated to decomposition it emits very toxic fumes of SOx and NOx.
  • Risk Codes
  • Molecular Structure Molecular Structure of 65057-90-1 (Talisomycin)
  • Hazard Symbols
  • Synonyms AntibioticBU 2231A; NSC 279496; Talisomycin; Talisomycin A; Tallysomycin A
  • PSA 881.89000
  • LogP -2.64720

Tallysomycin A Chemical Properties

IUPAC Name: [2-[2-[3-[[5-[[1-[[2-[4-[4-[[4-Amino-6-[3-(4-aminobutylamino)propylamino]-6-oxohexyl]carbamoyl]-1,3-thiazol-2-yl]-1,3-thiazol-2-yl]-1-(5-amino-3,4-dihydroxy-6-methyloxan-2-yl)oxy-2-hydroxyethyl]amino]-3-hydroxy-1-
oxobutan-2-yl]amino]-3-hydroxy-5-oxopentan-2-yl]amino]-2-[[6-amino-2-[3-amino-1-[(2,3-diamino-3-oxopropyl)amino]-3-oxopropyl]-5-methylpyrimidine-4-carbonyl]amino]-1-(1H-imidazol-5-yl)-3-oxopropoxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl] carbamate 
Molecular Formula: C68H11N22O27S2
Molecular Weight: 1732.12
Density: 1.58 g/cm3 
Melting Point: 210°C
Properties: white amorphous solid or powder.
Freely Rotating Bonds: 63
Polar Surface Area: 497.47 Å2
Index of Refraction: 1.686
Molar Refractivity: 416.38 cm3
Molar Volume: 1093.9 cm3
Polarizability: 165.06 ×10-24 cm3
Surface Tension: 108.1 dyne/cm 
The Cas Register Number  of Tallysomycin A is 65057-90-1.The chemical synonyms of Tallysomycin A (CAS NO.65057-90-1) are Talisomycin ; Antibiotic BU-2231A ; Bu-2231A ; N1-[4-Amino-5-[[3-[(4-aminobutyl)amino]propyl]carbamoyl]pentyl]-13-[(4-amino-4,6-dideoxy-α-L-talopyranosyl)oxy]-19-demethyl-12-hydroxybleomycinamide ; Talisomycin A ; Tallysomycin A .The molecular structure of Tallysomycin A (CAS NO.65057-90-1) is.

Tallysomycin A Uses

 Tallysomycin A (CAS NO.65057-90-1) is used as antineoplastic agent.

Tallysomycin A Toxicity Data With Reference

1.    

mmo-sat 50 ng/plate

     MUREAV    Mutation Research. 117 (1983),9.
2.    

dni-hmn:lym 50 mg/L

     MUREAV    Mutation Research. 112 (1983),119.
3.    

cy-hmn:lym 25 mg/L

     MUREAV    Mutation Research. 112 (1983),119.
4.    

ipr-mus LD50:19 mg/kg

     JANTAJ    Journal of Antibiotics. 31 (1978),667.
5.    

ipr-mus LD50: 19 mg/kg

     JANTAJ    Journal of Antibiotics. 31 (1978),667.
6.    

scu-mus LD50: 28 mg/kg

     USXXAM    United States Patent Document. (Commissioner of Patents and Trademarks, Washington, DC 20231) #4051237 .
7.    

ivn-mus LD50: 17 mg/kg

     JANTAJ    Journal of Antibiotics. 31 (1978),667.

Tallysomycin A Safety Profile

Poison by intraperitoneal, subcutaneous and intravenous routes. Human mutation data reported. When heated to decomposition it emits very toxic fumes of SOx and NOx.

Related Products

Hot Products

Post buying leads

About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

©2008 LookChem.com,License: ICP

NO.:Zhejiang16009103

complaints:service@lookchem.com Desktop View