Tegafur supplier | CasNO.17902-23-7

Name
Tegafur
EINECS 241-846-2
CAS No. 17902-23-7
Article Data63
CAS DataBase
Density 1.45 g/cm³
Solubility
Melting Point 171-173 °C(lit.)
Formula C₈H₉FN₂O₃
Boiling Point
Molecular Weight 200.169
Flash Point
Transport Information UN 2811 6.1/PG 2
Appearance white crystalline powder
Safety 22-36/37/39-45
Risk Codes 23/24/25
Molecular Structure
Hazard Symbols T
Synonyms 1-(2-Tetrahydrofuryl)-5-fluorouracil ; 1-(Tetrahydro-2-furanyl)-5-fluoro-2,4-pyrimidinedione;1-(Tetrahydrofuran-2-yl)-5-fluorouracil;2,4(1H,3H)Pyrimidinedione, 5-fluoro-1-(tetrahydro-2-furanyl)-;5-24-06-00285 (Beilstein Handbook Reference);5-Fluoro-1-(tetrahydro-2-furanyl)-2,4-pyrimidinedione;
PSA 64.09000
LogP -0.01530

Synthetic route

: tert-butyl 5-fluoro-2,6-dioxo-3-(tetrahydrofuran-2-yl)-3,6-dihydropyrimidine-1(2H)-carboxylate

: 17902-23-7
tegafur

Conditions

Conditions	Yield
With isopropyl alcohol at 75℃; for 4h; Inert atmosphere;	100%

: 51-21-8
5-fluorouracil

: 692-29-5
Succinic semialdehyde

: 17902-23-7
tegafur

Conditions

Conditions	Yield
With indium(III) bromide; 1,1,3,3-Tetramethyldisiloxane In tetrahydrofuran at 15 - 20℃; for 12h; Solvent; Reagent/catalyst; Temperature;	99.8%

: 1191-99-7
2,3-dihydro-2H-furan

: 51-21-8
5-fluorouracil

: 17902-23-7
tegafur

Conditions

Conditions	Yield
With bis(acetylacetonate)nickel(II); tris(2,2′-bipyridine)ruthenium(II) bis(tetrafluoroborate) In tetrahydrofuran at 25 - 30℃; Temperature; Solvent; Wavelength; Reagent/catalyst; Irradiation;	98.7%
With calcium chloride; trifluoroacetic acid In chloroform; N,N-dimethyl-formamide; toluene	85.2%
With dimethylmonochlorosilane; triethylamine In acetonitrile at 16℃; Temperature;	85%

: 51-21-8
5-fluorouracil

: 3333-44-6
tetrahydrofuran-2-yl benzoate

: 17902-23-7
tegafur

Conditions

Conditions	Yield
With sodium acetate; tetra-(n-butyl)ammonium iodide In dichloromethane; water at 35℃; for 2h; Solvent; Temperature; Reagent/catalyst;	95.2%

: 90162-98-4
5-Fluoro-2,6-dioxo-3-(tetrahydro-furan-2-yl)-3,6-dihydro-2H-pyrimidine-1-carbothioic acid S-octyl ester

: 17902-23-7
tegafur

Conditions

Conditions	Yield
With isopropylamine In diethyl ether Ambient temperature;	95%

: 109-99-9
tetrahydrofuran

: 51-21-8
5-fluorouracil

: 17902-23-7
tegafur

Conditions

Conditions	Yield
With dihydrogen peroxide; copper diacetate In N,N-dimethyl-formamide at 40℃; for 5h; Reagent/catalyst; Time; Solvent; Temperature;	92.35%
With carbon tetrabromide; potassium carbonate In ethanol; water at 50 - 60℃; for 9.5h; Temperature; Reagent/catalyst; Inert atmosphere;	82%
With 1-iodo-2,2,3,3,4,4,5,5,5-nonafluorobutane; caesium carbonate at 90℃; for 12h; Inert atmosphere; Sealed tube;	39%

: 1191-99-7
2,3-dihydro-2H-furan

: 51-21-8
5-fluorouracil

: 75-78-5
dimethylsilicon dichloride

: 17902-23-7
tegafur

Conditions

Conditions	Yield
With sodium hydroxide; triethylamine In chloroform; acetonitrile	85.5%
With pyridine In acetonitrile	75.4%

...Expand

: 65906-08-3
5-fluoro-1-(2-tetrahydrofuryl)-6-hydroxy-5-methoxycarbonyl-5,6-dihydrouracil

: 17902-23-7
tegafur

Conditions

Conditions	Yield
With trifluoroacetic acid In water at 0℃; for 1104h;	84%

: 70325-85-8
(4,4-Dimethoxy-butoxy)-trimethyl-silane

: 17242-85-2
5-fluoro-2,4-bis(trimethylsilyloxy)pyrimidine

: 17902-23-7
tegafur

Conditions

Conditions	Yield
With tin(IV) chloride In 1,2-dichloro-ethane; acetonitrile addition at 0 deg C, stirring at 23-25 deg C, 1h;	84%

: 13369-70-5
2-chlorotetrahydrofuran

: 51-21-8
5-fluorouracil

A: 17902-23-7
tegafur

B: 62987-05-7
1,3-bis(tetrahydro-2-furyl)-5-fluorouracil

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl acetamide at 30℃; for 5h;	A 75% B 80%

...Expand

: 110-89-4
piperidine

: 17902-23-7
tegafur

Conditions

Conditions	Yield
With pyridine	79.3%

: 62987-05-7
1,3-bis(tetrahydro-2-furyl)-5-fluorouracil

: 17902-23-7
tegafur

Conditions

Conditions	Yield
With water In ethanol at 50℃; for 2h;	76%

: 1608-67-9
2-acetoxytetrahydrofuran

: 51-21-8
5-fluorouracil

: 17902-23-7
tegafur

Conditions

Conditions	Yield
Stage #1: 2-acetoxytetrahydrofuran; 5-fluorouracil With 1,8-diazabicyclo[5.4.0]undec-7-ene In N,N-dimethyl-formamide at 90℃; for 24h; Sealed tube; Stage #2: With water In ethanol at 70℃; for 1.5h;	72%
In N,N-dimethyl-formamide at 140℃; for 2h;	53%
With ammonium sulfate; cesium chloride; 1,1,1,3,3,3-hexamethyl-disilazane 2.) MeCN, 25 deg C, 3 h; Yield given. Multistep reaction;

: 1191-99-7
2,3-dihydro-2H-furan

: 51-21-8
5-fluorouracil

: 7440-44-0
pyrographite

: 17902-23-7
tegafur

Conditions

Conditions	Yield
In pyridine; chloroform; water	72%

...Expand

: 1191-99-7
2,3-dihydro-2H-furan

: 51-21-8
5-fluorouracil

A: 17902-23-7
tegafur

B: 62987-05-7
1,3-bis(tetrahydro-2-furyl)-5-fluorouracil

Conditions

Conditions	Yield
With pyridine; phosphorus pentaoxide In chloroform	A 63% B n/a
With 4-Methyl-1-benzolsulfonsaeure-trimethylsilylester In pyridine; 1,2-dichloro-ethane at 75 - 80℃; for 1h;	A 41% B n/a
With pyridine hydrochloride In 1,2-dichloro-ethane at 75 - 80℃; Product distribution; other temperature, other solvents, other reagents;	A 1.73 g B n/a
With pyridine In 1,2-dichloro-ethane at 75 - 80℃; Product distribution; other temperature, other solvents, other reagents;	A 1.73 g B n/a

...Expand

: 1191-99-7
2,3-dihydro-2H-furan

: 51-21-8
5-fluorouracil

calcium bromide(CaBr2.2H2 O): calcium bromide(CaBr2.2H2 O)

: 17902-23-7
tegafur

Conditions

Conditions	Yield
In chloroform; N,N-dimethyl-formamide; acetone	62.5%

...Expand

: 1191-99-7
2,3-dihydro-2H-furan

: 51-21-8
5-fluorouracil

: Dimethylphenylsulfonium Perchlorate

: 17902-23-7
tegafur

Conditions

Conditions	Yield
In pyridine; chloroform; water	58.3%

...Expand

: 1191-99-7
2,3-dihydro-2H-furan

: 17242-85-2
5-fluoro-2,4-bis(trimethylsilyloxy)pyrimidine

: 17902-23-7
tegafur

Conditions

Conditions	Yield
With toluene-4-sulfonic acid In pyridine; 1,2-dichloro-ethane at 75 - 80℃; for 3h;	51%

: 1608-67-9
2-acetoxytetrahydrofuran

: 51-21-8
5-fluorouracil

A: 17902-23-7
tegafur

B: 63901-83-7
5-fluoro-3-(tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

C: 62987-05-7
1,3-bis(tetrahydro-2-furyl)-5-fluorouracil

Conditions

Conditions	Yield
With 1,8-diazabicyclo[5.4.0]undec-7-ene In N,N-dimethyl-formamide at 90℃; for 24h; Reagent/catalyst; Time; Sealed tube;	A 51% B 11% C 29%

...Expand

: 1191-99-7
2,3-dihydro-2H-furan

: 17242-85-2
5-fluoro-2,4-bis(trimethylsilyloxy)pyrimidine

A: 51-21-8
5-fluorouracil

B: 17902-23-7
tegafur

Conditions

Conditions	Yield
With pyridine hydrochloride In chloroform at 60 - 70℃; Product distribution; other temperature, other solvents;	A 0.6 g B 44.5%

...Expand

: 1608-67-9
2-acetoxytetrahydrofuran

: 51-21-8
5-fluorouracil

A: 17902-23-7
tegafur

B: 62987-05-7
1,3-bis(tetrahydro-2-furyl)-5-fluorouracil

Conditions

Conditions	Yield
With ammonium sulfate; cesium chloride; 1,1,1,3,3,3-hexamethyl-disilazane 2.) MeCN, 25 deg C, 2 h; Yield given. Multistep reaction. Yields of byproduct given;

...Expand

: 1608-67-9
2-acetoxytetrahydrofuran

: 1,3-dideuterio-5-fluorouracil

A: 17902-23-7
tegafur

B: 79994-85-7
C8H8(2)HFN2O3

C: 79994-86-8
C8H7(2)H2FN2O3

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 120℃; Mechanism; isotopic effect;

...Expand

: 65906-07-2
1-(2-tetrahydrofuryl)-5-methoxycarbonyluracil

A: 51-21-8
5-fluorouracil

B: 17902-23-7
tegafur

Conditions

Conditions	Yield
With sodium hydroxide; fluorine; acetic acid 1.) RT, 2.) H2O, 1 h, RT; Yield given. Multistep reaction;

: 65906-07-2
1-(2-tetrahydrofuryl)-5-methoxycarbonyluracil

: 17902-23-7
tegafur

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 43 percent / F2/N2 (25percent) / H2O / Ambient temperature 2: 84 percent / CF3COOH / H2O / 1104 h / 0 °C View Scheme
With hydrogenchloride; sodium hydroxide; ammonia; potassium carbonate; sodium sulfate In methanol; water; acetic acid

: 59-67-6
nicotinic acid

: 51-21-8
5-fluorouracil

: 17902-23-7
tegafur

Conditions

Conditions	Yield
In N-methyl-acetamide; chloroform

: 51-21-8
5-fluorouracil

2,3-tetrahydrofuran: 2,3-tetrahydrofuran

: 17902-23-7
tegafur

Conditions

Conditions	Yield
With tetramethlyammonium chloride In N-methyl-acetamide

: 1336-21-6
ammonium hydroxide

: 373-91-1
hypofluorous acid trifluoromethyl ester

: 18002-26-1
1-(tetrahydro-furan-2-yl)-uracil

: 17902-23-7
tegafur

Conditions

Conditions	Yield
With nitrogen In methanol; dichloromethane

...Expand

: 13369-70-5
2-chlorotetrahydrofuran

: 58138-78-6
bis-trimethylsilyl-5-fluoro-uracil

: 17902-23-7
tegafur

Conditions

Conditions	Yield
With ammonium hydroxide In tetrahydrofuran; methanol

: 1191-99-7
2,3-dihydro-2H-furan

aqueous K2 CO3: aqueous K2 CO3

: 17902-23-7
tegafur

Conditions

Conditions	Yield
tin(IV) chloride In 1,4-dioxane; chloroform; isopropyl alcohol

: 110-91-8
morpholine

: 50-00-0
formaldehyd

: 17902-23-7
tegafur

: 1062200-97-8
C13H18FN3O4

Conditions

Conditions	Yield
In tetrahydrofuran; water at 20℃; for 18h;	100%

...Expand

: 100-39-0
benzyl bromide

: 17902-23-7
tegafur

: 64504-15-0
3-(phenylmethyl)-1-(2-tetrahydrofuryl)-5-fluorouracil

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide; acetone at 50 - 60℃;	95%

: 17902-23-7
tegafur

: 1066-54-2
trimethylsilylacetylene

: 98653-14-6
1-(tetrahydrofuran-2-yl)-3-(m-nitrobenzyl)-5-fluorouracil

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide for 1h; Ambient temperature;	95%

: 2373-51-5
chloro-methylsulfanyl-methane

: 17902-23-7
tegafur

: 64504-18-3
3-methylthiomethyl-1-(tetrahydro-2-furyl)-5-fluorouracil

Conditions

Conditions	Yield
With potassium carbonate In dimethyl sulfoxide 1.) 1 h, below 10 deg C, 2.) room temp., 8 h;	93.9%

: 17902-23-7
tegafur

: 147-85-3
L-proline

: tegafur L-proline

Conditions

Conditions	Yield
In ethanol; acetone at 50℃; for 8h; Solvent; Temperature;	93.23%

: 5-(4-bromomethyl-3-nitrophenyl)-10,15,20-triphenylporphyrin

: 17902-23-7
tegafur

: 1029885-24-2
5-(α-tegafur-m-nitro-p-tolyl)-10,15,20-triphenylporphyrin

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 70℃; for 10h;	92.6%

: 17902-23-7
tegafur

: 107-07-3
2-chloro-ethanol

A: 55185-82-5
5-Fluoro-1,3-bis(2-hydroxyethyl)-uracil

B: 82178-07-2
N1-(2-furanidyl)-N3-(2-hydroxyethyl)-5-fluorouracil

Conditions

Conditions	Yield
With triethylamine In acetonitrile at 80℃; for 6h; Title compound not separated from byproducts;	A n/a B 91%

...Expand

: 17902-23-7
tegafur

: 98653-12-4
1-(o-nitrobenzyl)-3-acetyl-5-fluorouracil

: 98653-15-7
5-fluoro-3-(4-nitrobenzyl)-1-(tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide for 1h; Ambient temperature;	90%

: 17902-23-7
tegafur

: 3958-60-9
2-nitrophenylmethyl bromide

: 98653-13-5
1-(tetrahydrofuran-2-yl)-3-(o-nitrobenzyl)-5-fluorouracil

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide for 1h; Ambient temperature;	90%

: 1453-82-3
isonicotinamide

: 17902-23-7
tegafur

: (RS)-5-fluoro-1-(tetrahydrofuran-2-yl) pyrimidine-2,4 (1H,3H)-dione*isonicotinamide

Conditions

Conditions	Yield
In methanol at 60℃; for 120h;	88.23%

: 34040-64-7
p-methyloxycarbonylbenzyl chloride

: 17902-23-7
tegafur

: methyl 4-((5-fluoro-2,6-dioxo-3-(tetrahydrofuran-2-yl)-2,3-dihydropyrimidin-1(6H)-yl)methyl)-benzoate

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 20℃;	88%
With potassium carbonate In N,N-dimethyl-formamide at 20℃;

: 98-92-0
nicotinamide

: 17902-23-7
tegafur

: (RS)-5-fluoro-1-(tetrahydrofuran-2-yl) pyrimidine-2,4 (1H,3H)-dione*nicotinamide

Conditions

Conditions	Yield
In methanol at 60℃; for 120h;	87.93%

: 17902-23-7
tegafur

: 87-66-1
2-hydroxyresorcinol

: (RS)-5-fluoro-1-(tetrahydrofuran-2-yl) pyrimidine-2,4 (1H,3H)-dione*pyrogallol

Conditions

Conditions	Yield
In methanol for 0.5h; Milling;	87.43%

Tegafur Chemical Properties

IUPAC Name: 5-Fluoro-1-(oxolan-2-yl)pyrimidine-2,4-dione
Synonyms of 5-Fluoro-1-(tetrahydro-2-furyl)uracil (CAS NO.17902-23-7): 1-(2-Tetrahydrofuryl)-5-fluorouracil ; 1-(Tetrahydro-2-furanyl)-5-fluoro-2,4-pyrimidinedione ; 1-(Tetrahydrofuran-2-yl)-5-fluorouracil ; 2,4(1H,3H)Pyrimidinedione, 5-fluoro-1-(tetrahydro-2-furanyl)- ; 5-24-06-00285 (Beilstein Handbook Reference) ; 5-Fluoro-1-(tetrahydro-2-furanyl)-2,4-pyrimidinedione ; 5-Fluoro-1-(tetrahydro-2-furyl)uracil ; 5-Fluoro-1-(tetrahydro-3-furyl)uracil ; 5-Fluoro-1-(tetrahydrofuran-2-yl)uracil ; BRN 0525766 ; CCRIS 2762 ; Citofur ; Coparogin ; EINECS 241-846-2 ; Exonal ; FT-207 ; Furafluor ; Furflucil ; Lamar ; Lifril ; MJF-12264 ; N(sub 1)-(2'-Furanidyl)-5-fluouracil ; N(sub 1)-(2'-Furanidyl)-5-fluouracil [Czech] ; N(sub 1)-(2-Tetrahydrofuryl)-5-fluorouracil ; N1-(2-tetrahydrofuryl)-5-fluorouracil ; NSC-148958 ; Neberk ; Nitobanil ; Phthorafur ; Phthorafur [Czech] ; Racemic Ftorafur ; Riol ; Sinoflurol ; Sunfral ; Tefsiel C ; Tegafur ; Tegafurum ; Tegafurum [INN-Latin] ; UNII-1548R74NSZ ; Uracil, 1-(tetrahydrofuran-2-yl)-5-fluoro- ; Uracil, 5-fluoro-1-(tetrahydro-2-furyl)-
CAS NO: 17902-23-7
Classification Code: Antimetabolites ; Antimetabolites, antineoplastic ; Antineoplastic ; Antineoplastic Agents ; Drug / Therapeutic Agent ; Human Data ; Mutation data ; Noxae ; Reproductive Effect ; Tumor data
Molecular Formula: C₈H₉FN₂O₃
Molecular Weight: 200.1671
Molecular Structure:

Melting Point: 171-173 °C
H bond acceptors: 5
H bond donors: 1
Freely Rotating Bonds: 1
Polar Surface Area: 49.85 Å²
Index of Refraction: 1.557
Molar Refractivity: 44.28 cm³
Molar Volume: 137.4 cm³
Surface Tension: 51.1 dyne/cm
Density of 5-Fluoro-1-(tetrahydro-2-furyl)uracil (CAS NO.17902-23-7): 1.45 g/cm³

Tegafur Uses

5-Fluoro-1-(tetrahydro-2-furyl)uracil (CAS NO.17902-23-7) can be used as an antineoplastic

Tegafur Production

5-Fluoro-1-(tetrahydro-2-furyl)uracil (CAS NO.17902-23-7) can be derived from condensation 5 - fluorouracil and 2 - acetoxy-tetrahydrofuran with the yield of the Act only about 15%.
Another production method is based on the synthesis of fluoride withthe starting material of 5 - fluorouracil, 6 methyl-2, and 3-methyl silicone alkyl ammonium chloride.

Tegafur Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
cat	LD50	oral	36mg/kg (36mg/kg)	BEHAVIORAL: TREMOR GASTROINTESTINAL: NAUSEA OR VOMITING	Journal of Pharmaceutical Sciences. Vol. 73, Pg. 212, 1984.
dog	LD50	oral	34mg/kg (34mg/kg)	BEHAVIORAL: TREMOR VASCULAR: OTHER CHANGES GASTROINTESTINAL: NAUSEA OR VOMITING	Oyo Yakuri. Pharmacometrics. Vol. 20, Pg. 1009, 1980.
human	LDLo	intravenous	640mg/kg/8D (640mg/kg)	BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION GASTROINTESTINAL: NAUSEA OR VOMITING	Cancer Vol. 36, Pg. 103, 1975.
human	TDLo	intravenous	23mg/kg (23mg/kg)	BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS"	Cancer Vol. 36, Pg. 103, 1975.
man	TDLo	oral	197mg/kg/23D- (197mg/kg)	BRAIN AND COVERINGS: ENCEPHALITIS BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) BEHAVIORAL: ANTIPSYCHOTIC	Internal Medicine. Vol. 31, Pg. 828, 1992.
mouse	LD50	intraperitoneal	493mg/kg (493mg/kg)		National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. Vol. JAN1986,
mouse	LD50	intravenous	750mg/kg (750mg/kg)		United States Patent Document. Vol. #4130648,
mouse	LD50	oral	775mg/kg (775mg/kg)		Yaoxue Tongbao. Bulletin of Pharmacology. Vol. 22, Pg. 27, 1987.
mouse	LD50	subcutaneous	760mg/kg (760mg/kg)	GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" GASTROINTESTINAL: NAUSEA OR VOMITING	Oyo Yakuri. Pharmacometrics. Vol. 5, Pg. 569, 1971.
rabbit	LD50	oral	44mg/kg (44mg/kg)	VASCULAR: OTHER CHANGES	Oyo Yakuri. Pharmacometrics. Vol. 20, Pg. 1009, 1980.
rabbit	LD50	unreported	40mg/kg (40mg/kg)		Eksperimental'naya i Klinicheskaya Farmakoterapiya. Vol. 7, Pg. 100, 1977.
rat	LD50	intraperitoneal	700mg/kg (700mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 6, Pg. 2911, 1978.
rat	LD50	intravenous	685mg/kg (685mg/kg)		Gan to Kagaku Ryoho. Cancer and Chemotherapy. Vol. 10, Pg. 1987, 1983.
rat	LD50	oral	930mg/kg (930mg/kg)	GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 6, Pg. 2911, 1978.
rat	LD50	subcutaneous	600mg/kg (600mg/kg)	BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 6, Pg. 2911, 1978.

Tegafur Consensus Reports

Reported in EPA TSCA Inventory.

Tegafur Safety Profile

Poison by ingestion. Moderately toxic to humans by intravenous route. Moderately toxic experimentally by intraperitoneal, intravenous, and subcutaneous routes. Experimental teratogenic data. Human systemic effects: nausea and vomiting. Experimental reproductive effects. Questionable human carcinogen producing gastrointestinal tumors. Human mutation data reported. Used as an anti-cancer agent. When heated to decomposition it emits very toxic fumes of F⁻ and NO_x.
Safety Information of 5-Fluoro-1-(tetrahydro-2-furyl)uracil (CAS NO.17902-23-7).
Hazard Codes: Toxic T
Risk Statements: 23/24/25
R23/24/25: Toxic by inhalation, in contact with skin and if swallowed.
Safety Statements: 22-36/37/39-45
S22: Do not breathe dust.
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: UN 2811 6.1/PG 2
WGK Germany: 3
RTECS: YR0450000

Product Name

Tegafur

Synthetic route

Tegafur Chemical Properties

Tegafur Uses

Tegafur Production

Tegafur Toxicity Data With Reference

Tegafur Consensus Reports

Tegafur Safety Profile

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