Tetrabromophthalic anhydride supplier

Name
Tetrabromophthalic anhydride
EINECS 211-185-4
CAS No. 632-79-1
Article Data10
CAS DataBase
Density 2.771 g/cm³
Solubility hydrolysis with water
Melting Point 269-271 °C(lit.)
Formula C₈Br₄O₃
Boiling Point 540.5 °C at 760 mmHg
Molecular Weight 463.702
Flash Point 280.7 °C
Transport Information
Appearance white to light yellow powder
Safety 26-37/39-24/25
Risk Codes 36/37/38
Molecular Structure
Hazard Symbols Xi
Synonyms Phthalicanhydride, tetrabromo- (6CI,7CI,8CI);3,4,5,6-Tetrabromophthalic anhydride;Bromphthal;FG 4000;FireMaster PHT 4;NSC 4874;PHT 4;Saytex RB 49;Tetrabromophthalic acid anhydride;
PSA 43.37000
LogP 4.04720

Synthetic route

: 85-44-9
phthalic anhydride

: 632-79-1
Tetrabromophthalic anhydride

Conditions

Conditions	Yield
With sulfuric acid; bromine; tin(IV) chloride at 30 - 80℃; for 13h; Reagent/catalyst; Temperature;	95.1%
With sulfuric acid; bromine; iodine
With sulfuric acid; bromine at 60℃; anschliessend Erhitzen auf 200grad;
With sulfuric acid; bromine at 60℃; anschliessend Erhitzen auf 200grad;

: 13810-83-8
tetrabromobenzene-1,2-dicarboxylic acid

: 632-79-1
Tetrabromophthalic anhydride

Conditions

Conditions	Yield
durch Sublimation;

: 85-44-9
phthalic anhydride

: 7664-93-9
sulfuric acid

: 7726-95-6
bromine

: 632-79-1
Tetrabromophthalic anhydride

Conditions

Conditions	Yield
at 60℃; anschl. Erhitzen auf 200grad;
at 60℃; anschl. Erhitzen auf 200grad;

...Expand

: 86-90-8
4-bromophthalic anhydride

: 632-79-1
Tetrabromophthalic anhydride

Conditions

Conditions	Yield
With iron(III) chloride; sulfuric acid; bromine; iodine at 50 - 150℃; for 3h;

: 110-89-4
piperidine

: 632-79-1
Tetrabromophthalic anhydride

: 80992-18-3
4,5,6,7-tetrabromo-3-hydroxy-3-piperidinophthalide

Conditions

Conditions	Yield
In ethyl acetate for 1h; Heating;	99%

: 632-79-1
Tetrabromophthalic anhydride

: 35303-76-5
4-(2-aminoethyl)benzenesulfonamide

: 1454891-19-0
4-(2-(4,5,6,7-tetrabromo-1,3-dioxoisoindolin-2-yl)ethyl)benzenesulfonamide

Conditions

Conditions	Yield
With acetic acid at 130℃; for 1.5h; Inert atmosphere;	99%
With acetic acid for 12h; Reflux;

: 632-79-1
Tetrabromophthalic anhydride

: 56073-96-2
methyl N-[5(6)-(4-aminophenylsulfanyl)benzimidazol-2-yl]carbamate

: sodium; 2,3,4,5-tetrabromo-6-[4-(2-methoxycarbonylamino-1H-benzoimidazol-5-ylsulfanyl)-phenylcarbamoyl]-benzoate

Conditions

Conditions	Yield
With sodium acetate; acetic acid at 40 - 45℃; for 3h;	98%

: 26782-71-8
D-tert-leucine

: 632-79-1
Tetrabromophthalic anhydride

: N-tetrabromophthaloyl-(R)-tert-leucine

Conditions

Conditions	Yield
With triethylamine In toluene Reflux;	97%

: 632-79-1
Tetrabromophthalic anhydride

: 13810-83-8
tetrabromobenzene-1,2-dicarboxylic acid

Conditions

Conditions	Yield
Stage #1: Tetrabromophthalic anhydride With potassium hydroxide In water for 0.5h; Inert atmosphere; Reflux; Stage #2: With hydrogenchloride In water at 20℃; Inert atmosphere;	96%

: 1653-40-3
6-methylheptanol

: 632-79-1
Tetrabromophthalic anhydride

: isooctyl 2,3,4,5-tetrabromobenzoate

Conditions

Conditions	Yield
With triethylamine In N,N-dimethyl acetamide at 55℃; for 3.5h; Temperature; Concentration; Reagent/catalyst; Solvent;	95.6%

: 632-79-1
Tetrabromophthalic anhydride

: 56765-79-8
3,4-dicyanoaniline

: 4-(tetrabromophthalimido)phthalonitrile

Conditions

Conditions	Yield
In acetic acid for 2h; Reflux;	95.5%

: 632-79-1
Tetrabromophthalic anhydride

: 24407-32-7
3,4,5,6-tetrabromophthalimide

Conditions

Conditions	Yield
With iron(III) chloride; guanidine hydrochloride; triethylamine at 60℃; for 0.0833333h;	95%
With formamide In neat (no solvent) for 0.333333h; Reagent/catalyst; Milling; Heating; Green chemistry;	94%
With choline chloride; urea at 140℃; for 1h; Green chemistry;	92%
With potassium cyanate In N,N-dimethyl-formamide for 0.05h; microwave irradiation;	89%

: 632-79-1
Tetrabromophthalic anhydride

: 35264-29-0
4-(hydrazinecarbonyl)benzene-1-sulfonamide

: 4-sulfamoyl-N-(4,5,6,7-tetrabromo-1,3-dioxoisoindolin-2-yl)benzamide

Conditions

Conditions	Yield
With sodium acetate; acetic acid for 12h; Reflux;	95%

: 632-79-1
Tetrabromophthalic anhydride

: 24313-88-0
3,4,5-Trimethoxyaniline

: 1293923-48-4
4,5,6,7-tetrabromo-2-(3,4,5-trimethoxyphenyl)isoindoline-1,3-dione

Conditions

Conditions	Yield
With acetic acid for 12h; Reflux;	94%

: 632-79-1
Tetrabromophthalic anhydride

: 13755-95-8
2,3-diamino-1,4-naphthoquinone

: 1333335-11-7
1,2,3,4-tetrabromonaphtho[2',3':4,5]imidazo[2,1-a]isoindole-6,11,13-trione

Conditions

Conditions	Yield
With acetic acid In water at 20℃; Reflux;	94%

: 632-79-1
Tetrabromophthalic anhydride

: 138-37-4
mafenide hydrochloride

: 4-((4,5,6,7-tetrabromo-1,3-dioxoisoindolin-2-yl)methyl)benzenesulfonamide hydrochloride

Conditions

Conditions	Yield
With acetic acid at 130℃; for 1.5h; Inert atmosphere;	94%

: 860994-58-7
1-((1R,2R)-2-aminocyclohexyl)-3-(3,5-bis(trifluoromethyl)phenyl)thiourea

: 632-79-1
Tetrabromophthalic anhydride

: 2-(((1R,2R)-2-(3-(3,5-bis(trifluoromethyl)phenyl)thioureido)cyclohexyl)carbamoyl)-3,4,5,6-tetrabromobenzoic acid

Conditions

Conditions	Yield
With triethylamine In tetrahydrofuran for 8h; Inert atmosphere;	94%
With dmap In tetrahydrofuran at 20℃; for 2h;
With triethylamine In tetrahydrofuran Inert atmosphere; Schlenk technique;

: 632-79-1
Tetrabromophthalic anhydride

: 57-13-6
urea

: copper dichloride

: 25397-26-6
brominated copper phthalocyanine

Conditions

Conditions	Yield
With titanium tetrachloride In 1,2,3-trichlorobenzene at 100 - 195℃; for 3h;	93.9%

...Expand

: 632-79-1
Tetrabromophthalic anhydride

: 99-92-3
4-Aminoacetophenone

: 2-(4-acetylphenyl)-4,5,6,7-tetrabromoisoindoline-1,3-dione

Conditions

Conditions	Yield
With sodium acetate; acetic acid for 12h; Reflux;	93%

: 110-89-4
piperidine

: 632-79-1
Tetrabromophthalic anhydride

: 80992-17-2
piperidinium 3,4,5,6-tetrabromo-2-piperidinocarbonylbenzoate

Conditions

Conditions	Yield
In benzene	92%

: 632-79-1
Tetrabromophthalic anhydride

: 51-45-6
histamine

: 4,5,6,7-tetrabromo-2-[2-(1H-imidazol-4-yl)-ethyl]-isoindole-1,3-dione

Conditions

Conditions	Yield
In toluene for 5h; Heating;	92%
In toluene Condensation; Heating;
In toluene for 3h; Condensation; Heating; Dean-Stark conditions;

: 632-79-1
Tetrabromophthalic anhydride

: 1073606-09-3
C15H14BrN

: 107470-20-2
4,5,6,7-tetrabromo-2-(4-bromo-phenyl)-isoindoline-1,3-dione

Conditions

Conditions	Yield
In ethanol for 1h; Reflux;	92%

: 632-79-1
Tetrabromophthalic anhydride

: 98-18-0
m-aminobenzenesulfonamide

: 1454891-20-3
3-(4,5,6,7-tetrabromo-1,3-dioxoisoindolin-2-yl)benzenesulfonamide

Conditions

Conditions	Yield
With acetic acid at 130℃; for 2h; Inert atmosphere;	92%

: 632-79-1
Tetrabromophthalic anhydride

: 1954-94-5
4-amino-2-chlorobenzenesulfonamide

: 1454891-23-6
3-chloro-4-(4,5,6,7-tetrabromo-1,3-dioxoisoindolin-2-yl)benzenesulfonamide

Conditions

Conditions	Yield
With acetic acid at 130℃; for 12h; Inert atmosphere;	92%

: 83-07-8
4-amino-2,3-dimethyl-1-phenylpyrazolin-5-one

: 632-79-1
Tetrabromophthalic anhydride

: N-antipyrine-tetrabromophthalamic acid

Conditions

Conditions	Yield
In diethyl ether	91.09%

: 632-79-1
Tetrabromophthalic anhydride

: 63-74-1
sulfanilamide

: 1454891-17-8
4-(4,5,6,7-tetrabromo-1,3-dioxoisoindolin-2-yl)benzenesulfonamide

Conditions

Conditions	Yield
With acetic acid for 20h; Reflux;	91%
With acetic acid at 130℃; for 12h; Inert atmosphere;	75%

: 223723-47-5
3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-benzopyran-2-carbohydrazide

: 632-79-1
Tetrabromophthalic anhydride

: C22H18Br4N2O5

Conditions

Conditions	Yield
With acetic acid for 2h; Reflux;	91%

: 632-79-1
Tetrabromophthalic anhydride

: 2368-83-4
4-amino-2-fluorobenzenesulfonamide

: 1454891-22-5
3-fluoro-4-(4,5,6,7-tetrabromo-1,3-dioxoisoindolin-2-yl)benzenesulfonamide

Conditions

Conditions	Yield
With acetic acid at 130℃; for 12h; Inert atmosphere;	90%

: 632-79-1
Tetrabromophthalic anhydride

: 1094798-12-5
4-amino-2-bromobenzenesulfonamide

: 1454891-24-7
3-bromo-4-(4,5,6,7-tetrabromo-1,3-dioxoisoindolin-2-yl)benzenesulfonamide

Conditions

Conditions	Yield
With acetic acid at 130℃; for 12h; Inert atmosphere;	90%

: 632-79-1
Tetrabromophthalic anhydride

: 1-(2-(((1R,2S)-1-amino-2,3-dihydro-1H-inden-2-yl)oxy)-5-(trifluoromethyl)phenyl)-3-(3,5-bis(trifluoromethyl)phenyl)urea

: C33H18Br4F9N3O5

Conditions

Conditions	Yield
With triethylamine In tetrahydrofuran for 8h; Inert atmosphere;	90%

: 632-79-1
Tetrabromophthalic anhydride

: C25H18F9N3OS

: 2-(((1R,2R)-2-(2-(3-(3,5-bis(trifluoromethyl)phenyl)thioureido)-4-(trifluoromethyl)phenoxy)-2,3-dihydro-1H-inden-1-yl)carbamoyl)-3,4,5,6-tetrabromobenzoic acid

Conditions

Conditions	Yield
With triethylamine In tetrahydrofuran for 8h; Inert atmosphere;	90%

: 150-19-6
O-methylresorcine

: 632-79-1
Tetrabromophthalic anhydride

: 4,5,6,7-tetrabromo-3’,6’-dimethoxyfluorescein

Conditions

Conditions	Yield
With niobium pentachloride In methanesulfonic acid at 95 - 100℃; for 1.66667h; Friedel-Crafts Acylation; Inert atmosphere;	90%
With Zn0.95*Ti0.05O In neat (no solvent) at 160℃; for 4h; Green chemistry;	66%

: 632-79-1
Tetrabromophthalic anhydride

: 24544-04-5
2,6-diisopropylbenzenamine

: 4,5,6,7-tetrabromo-2-(2,6-diisopropylphenyl)isoindoline-1,3-dione

Conditions

Conditions	Yield
With acetic acid at 140℃; for 12h;	90%

Tetrabromophthalic anhydride Chemical Properties

The Molecular formula of 3,4,5,6-TETRABROMOPHTHALIC ANHYDRIDE(632-79-1): C₈Br₄O₃
The Molecular Weight of 3,4,5,6-TETRABROMOPHTHALIC ANHYDRIDE(632-79-1): 463.7
Molecular Structure :

EINECS: 211-185-4
Index of Refraction: 1.725
Molar Refractivity: 66.44 cm³
Molar Volume: 167.3 cm³
Polarizability: 26.33 10^-24 cm³
Surface Tension: 72 dyne/cm
Density: 2.771 g/cm³
Boiling Point: 540.5 °C at 760 mmHg
Flash Point: 280.7 °C
Enthalpy of Vaporization: 81.81 kJ/mol
Vapour Pressure: 9.54E-12 mmHg at 25°C
Water Solubility: hydrolysis
IUPAC Name: 4,5,6,7-tetrabromo-2-benzofuran-1,3-dione
Synonyms: 1,3-Isobenzofurandione, 4,5,6,7-tetrabromo-;1,3-Isobenzofurandione,4,5,6,7-tetrabromo-;4,5,6,7-Tetrabromo-2-benzofuran-1,3-dione;4,5,6,7-tetrabromo-3-isobenzofurandione;bromophthal;3,4,5,6-Tetrabromophthalic anhydride;3,4,5,6-tetrabromophthalicanhydride;3-Isobenzofurandione,4,5,6,7-tetrabromo-1;

Tetrabromophthalic anhydride Toxicity Data With Reference

1.	eye-rbt 100 mg MLD	NTIS** National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) OTS0523271 .
2.	orl-rat LD50:>10 g/kg	NTIS** National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) OTS0539755 .
3.	ihl-rat LC :>10,920 mg/m3/4H	NTIS** National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) OTS0522251 .
4.	skn-rbt LD50:>10 g/kg	NTIS** National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) OTS0522251 .
5.	skn-gpg LD50:>1 g/kg	NTIS** National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) OTS0521611 .

Tetrabromophthalic anhydride Safety Profile

Low toxicity by ingestion, inhalation, and skin contact. A mild eye irritant. When heated to decomposition it emits toxic vapors of Br⁻.
The Hazard Codes of 3,4,5,6-TETRABROMOPHTHALIC ANHYDRIDE(632-79-1):

Xi
HS Code: 29173911
The Risk Statements information of 3,4,5,6-TETRABROMOPHTHALIC ANHYDRIDE(632-79-1):
36/37/38: Irritating to eyes, respiratory system and skin
The Safety Statements information of 3,4,5,6-TETRABROMOPHTHALIC ANHYDRIDE(632-79-1):
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
24/25: Avoid contact with skin and eyes
37/39: Wear suitable gloves and eye/face protection
WGK Germany: 2
RTECS: TI3350000

Product Name

Tetrabromophthalic anhydride

Synthetic route

Tetrabromophthalic anhydride Chemical Properties

Tetrabromophthalic anhydride Toxicity Data With Reference

Tetrabromophthalic anhydride Safety Profile

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