Product Name

  • Name

    Thioproperazine

  • EINECS 206-262-4
  • CAS No. 316-81-4
  • Article Data4
  • CAS DataBase
  • Density 1.237g/cm3
  • Solubility
  • Melting Point 140ºC
  • Formula C22H30 N4 O2 S2
  • Boiling Point 612.2°Cat760mmHg
  • Molecular Weight 446.638
  • Flash Point 324°C
  • Transport Information
  • Appearance
  • Safety Moderately toxic by ingestion. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of SOx and NOx.
  • Risk Codes
  • Molecular Structure Molecular Structure of 316-81-4 (Thioproperazine)
  • Hazard Symbols
  • Synonyms Phenothiazine-2-sulfonamide,N,N-dimethyl-10-[3-(4-methyl-1-piperazinyl)propyl]- (6CI,8CI); 7843RP;Cephalmin;N,N-Dimethyl-10-[3-(4-methyl-1-piperazinyl)propyl]-2-phenothiazinesulfonamide;RP 7843; SKF 5883; Sulfenazin; Thioperazine; Thioproperazine; Tioproperazin
  • PSA 80.78000
  • LogP 4.19870

Thioproperazine Chemical Properties

IUPAC Name:  N,N-Dimethyl-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine-2-sulfonamide
The MF of Thioperazine (CAS NO.316-81-4) is C22H30N4O2S2.

                 
The MW of Thioperazine (CAS NO.316-81-4) is 446.63.
Synonyms of Thioperazine (CAS NO.316-81-4): N,N-Dimethyl-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine-2-sulfonamide ; 10H-Phenothiazine-2-sulfonamide, N,N-dimethyl-10-[3-(4-methyl-1-piperazinyl)propyl]- ; Cephalmin;Phenothiazine-2-sulfonamide, N,N-dimethyl-10-[3-(4-methyl-1-piperazinyl)propyl]- ; Sulfenazin
Solubility in water: 3.6 mg/L (25 °C)
Index of Refraction: 1.615 
EINECS: 206-262-4
Density: 1.237 g/ml 
Flash Point: 324 °C
Boiling Point: 612.2 °C
Melting Point: 140 °C

Thioproperazine Uses

  Thioperazine (CAS NO.316-81-4) is used in medicine, pesticide manufacturing.

Thioproperazine Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 130mg/kg (130mg/kg)   Psychopharmacology Service Center, Bulletin. Vol. 2, Pg. 17, 1963.
mouse LD50 intravenous 70mg/kg (70mg/kg)   Psychopharmacology Service Center, Bulletin. Vol. 2, Pg. 17, 1963.
mouse LD50 oral 830mg/kg (830mg/kg) BEHAVIORAL: ANTIPSYCHOTIC Developments in Neuroscience Vol. 7, Pg. 45, 1980.
mouse LD50 subcutaneous 500mg/kg (500mg/kg)   Psychopharmacology Service Center, Bulletin. Vol. 2, Pg. 17, 1963.
rat LD50 intravenous 25mg/kg (25mg/kg)   Therapie. Vol. 18, Pg. 373, 1963.

Thioproperazine Safety Profile

Moderately toxic by ingestion. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of SOx and NOx.

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