Tipifarnib supplier | CasNO.192185-72-1

Name
Tipifarnib
EINECS
CAS No. 192185-72-1
Article Data8
CAS DataBase
Density 1.334 g/cm³
Solubility
Melting Point 211-213 °C (dec.)
Formula C₂₇H₂₂Cl₂N₄O
Boiling Point 681.725 °C at 760 mmHg
Molecular Weight 489.404
Flash Point 366.094 °C
Transport Information
Appearance Off-white to pale beige solid
Safety
Risk Codes
Molecular Structure
Hazard Symbols
Synonyms S1453_Selleck;Zarnestra;Tipifarnib (Zarnestra);Tipifarnib;
PSA 65.84000
LogP 6.19670

Tipifarnib Specification

The Tipifarnib with the cas number 192185-72-1 is also called 2(1H)-Quinolinone,6-[(R)-amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-. The IUPAC name is 6-[(R)-amino-(4-chlorophenyl)-(3-methylimidazol-4-yl)methyl]-4-(3-
chlorophenyl)-1-methylquinolin-2-one. Its molecular formula is C₂₇H₂₂Cl₂N₄O. It is farnesyltranstransferase inhibitor.

The properties of the chemical are: (1)ACD/LogP: 4.94; (2)# of Rule of 5 Violations: 0 ; (3)#H bond acceptors: 5; (4)#H bond donors: 2; (5)#Freely Rotating Bonds: 5; (6)Polar Surface Area: 41.37 Å²; (7)Index of Refraction: 1.671; (8)Molar Refractivity: 137.33 cm³; (9)Molar Volume: 366.8 cm³; (10)Polarizability: 54.44×10^-24cm³; (11)Surface Tension: 51.2 dyne/cm ; (12)Enthalpy of Vaporization: 100.02 kJ/mol ; (13)Vapour Pressure: 1.94×10^-18 mmHg at 25°C.

You can still convert the following datas into molecular structure:
(1)SMILES: Clc1cccc(c1)C=3c2cc(ccc2N(C(=O)C=3)C)[C@@](N)(c4cncn4C)c5ccc(Cl)cc5
(2)InChI: InChI=1/C27H22Cl2N4O/c1-32-16-31-15-25(32)27(30,18-6-9-20(28)10-7-18)19-8-11-24-23(13-19)22(14-26(34)33(24)2)17-4-3-5-21(29)12-17/h3-16H,30H2,1-2H3/t27-/m1/s1
(3)InChIKey: PLHJCIYEEKOWNM-HHHXNRCGBH

Product Name

Tipifarnib

Tipifarnib Specification

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