-
Name
TOLCAINE HYCROCHLORIDE
- EINECS
- CAS No. 33697-73-3
- Density
- Solubility
- Melting Point
- Formula C18H29NO2•ClH
- Boiling Point
- Molecular Weight 327.94
- Flash Point
- Transport Information
- Appearance
- Safety Poison by ingestion and intravenous routes. Moderately toxic by subcutaneous route. When heated to decomposition it emits toxic fumes of NOx and HCl.
- Risk Codes
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Molecular Structure
- Hazard Symbols
- Synonyms
- PSA
- LogP
Tolcaine hycrochloride Chemical Properties
IUPAC Name: 1-(2-Methylphenoxy)-3-(2,2,5,5-tetramethylpyrrolidin-1-yl)propan-2-ol hydrochloride
Molecular Formula: C18H29NO2•ClH
Molecular Weight: 327.94
Freely Rotating Bonds: 6
Polar Surface Area: 21.7 Å2
Flash Point: 198.7 °C
Enthalpy of Vaporization: 69.23 kJ/mol
Boiling Point: 405 °C at 760 mmHg
Vapour Pressure: 2.76E-07 mmHg at 25°C
The Cas Register Number of Tolcaine hycrochloride is 33697-73-3 .The chemical synonyms of Tolcaine hycrochloride (CAS NO.33697-73-3) are 1-Pyrrolidineethanol, 2,2,5,5-tetramethyl-alpha-((o-tolyloxy)methyl)-, hydrochloride ; 1-Pyrrolidineethanol, alpha-((2-methylphenoxy)methyl)-2,2,5,5-tetramethyl-, hydrochloride ; alpha-((2-Methylphenoxy)methyl)-2,2,5,5-tetramethyl-1-pyrrolidineethanol hydrochloride and Lotucaine hydrochloride .The molecular structure of Tolcaine hycrochloride (CAS NO.33697-73-3) is.png)
.
Tolcaine hycrochloride Uses
Tolcaine hycrochloride (CAS NO.33697-73-3) is used as organic intermediate.
Tolcaine hycrochloride Toxicity Data With Reference
| 1. | orl-rat LD50:418 mg/kg | BCFAAI Bollettino Chimico Farmaceutico. 110 (1971),330. | ||
| 2. | scu-rat LD50:795 mg/kg | BCFAAI Bollettino Chimico Farmaceutico. 110 (1971),330. | ||
| 3. | ivn-rat LD50:32 mg/kg | BCFAAI Bollettino Chimico Farmaceutico. 110 (1971),330. | ||
| 4. | orl-mus LD50:355 mg/kg | BCFAAI Bollettino Chimico Farmaceutico. 110 (1971),330. | ||
| 5. | scu-mus LD50:729 mg/kg | BCFAAI Bollettino Chimico Farmaceutico. 110 (1971),330. | ||
| 6. | ivn-mus LD50:22 mg/kg | BCFAAI Bollettino Chimico Farmaceutico. 110 (1971),330. | ||
| 7. | ivn-cat LDLo:14 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 23 (1973),1596. |
Tolcaine hycrochloride Safety Profile
Poison by ingestion and intravenous routes. Moderately toxic by subcutaneous route. When heated to decomposition it emits toxic fumes of NOx and HCl.
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