Fluproquazone

 Molecule structure of Tormosyl (CAS NO.40507-23-1) :

IUPAC Name: 4-(4-fluorophenyl)-7-methyl-1-propan-2-ylquinazolin-2-one 
Molecular Weight: 296.338783 g/mol
Molecular Formula: C₁₈H₁₇FN₂O 
Density: 1.18 g/cm³ 
Boiling Point: 436.6 °C at 760 mmHg
Flash Point: 217.9 °C
Index of Refraction: 1.596
Molar Refractivity: 85.03 cm³
Molar Volume: 249.8 cm³
Polarizability: 33.7×10^-24 cm³
Surface Tension: 38.4 dyne/cm
Enthalpy of Vaporization: 69.31 kJ/mol 
Vapour Pressure: 7.98E-08 mmHg at 25 °C
XLogP3-AA: 4.1
H-Bond Acceptor: 2
Rotatable Bond Count: 2
Exact Mass: 296.132491
MonoIsotopic Mass: 296.132491
Topological Polar Surface Area: 32.7
Heavy Atom Count: 22
Complexity: 454
Canonical SMILES: CC1=CC2=C(C=C1)C(=NC(=O)N2C(C)C)C3=CC=C(C=C3)F
InChI: InChI=1S/C18H17FN2O/c1-11(2)21-16-10-12(3)4-9-15(16)17(20-18(21)22)13-5-7-14(19)8-6-13/h4-11H,1-3H3
InChIKey of Tormosyl (CAS NO.40507-23-1) : ZWOUXWWGKJBAHQ-UHFFFAOYSA-N

 Tormosyl (CAS NO.40507-23-1) is mainly used in the treatment of arthritis and post-operative pain.

Moderately toxic by ingestion and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of F⁻ and NO_x.

 Tormosyl (CAS NO.40507-23-1) is also called 1-Isopropyl-7-methyl-4-(p-fluorophenyl)-2(1H)-quinazolinone ; 4-(4-Fluorophenyl)-7-methyl-1-(1-methylethyl)-2(1H)-quinazolinone ; 4-(p-Fluorophenyl)-1-isopropyl-7-methyl-2(1H)-quinazolinone ; 4-Fluorphenyl-1-isopropyl-7-methyl-2(1H)-chinazolinon ; 4-Fluorphenyl-1-isopropyl-7-methyl-2(1H)-chinazolinon [German] ; 5-24-04-00375 (Beilstein Handbook Reference) ; BRN 0891838 ; Fluproquazona ; Fluproquazona [INN-Spanish] ; Fluproquazone ; Fluproquazonum ; Fluproquazonum [INN-Latin] ; RF 46-790 ; SaH 46-790 . Tormosyl (CAS NO.40507-23-1) is a quinazolinone derivative with potent analgesic and antipyretic effects and also anti-inflammatory action. It has been shown to be effective in a variety of animal species after both oral and parenteral administration, and has a duration of action of several hours. The compound is many times more potent than acetylsalicylic acid and clinically generally resembles ibuprofen and indoprofen in its pharmacological effects, but with significantly less ulcerogenic activity.