Product Name

  • Name

    Trimeprazine tartrate

  • EINECS 224-368-9
  • CAS No. 4330-99-8
  • Article Data1
  • CAS DataBase
  • Density
  • Solubility
  • Melting Point 153-155oC
  • Formula 2(C18H22N2S).C4H6O6
  • Boiling Point
  • Molecular Weight 746.992
  • Flash Point
  • Transport Information
  • Appearance
  • Safety 36
  • Risk Codes 20/21/22
  • Molecular Structure Molecular Structure of 4330-99-8 (Trimeprazine tartrate )
  • Hazard Symbols Xn
  • Synonyms Alimemazine tartrate; N,N,2-Trimethyl-3-phenothiazin-10-yl-propan-1-amine tartrate
  • PSA 178.62000
  • LogP 6.98140

Synthetic route

cysteamine radical
40055-94-5

cysteamine radical

trimeprazine semitartrate
4330-99-8

trimeprazine semitartrate

2C18H22N2S*C4H6O6*2H(1+)
1175-88-8, 2015-31-8, 4330-99-8, 14101-45-2, 21287-43-4, 39832-33-2, 66634-41-1

2C18H22N2S*C4H6O6*2H(1+)

Conditions
ConditionsYield
In water Rate constant; pH 6.5, N2O;
2-hydroxy-ethylsulfanyl
68570-60-5

2-hydroxy-ethylsulfanyl

trimeprazine semitartrate
4330-99-8

trimeprazine semitartrate

2C18H22N2S*C4H6O6*2H(1+)
1175-88-8, 2015-31-8, 4330-99-8, 14101-45-2, 21287-43-4, 39832-33-2, 66634-41-1

2C18H22N2S*C4H6O6*2H(1+)

Conditions
ConditionsYield
In water Rate constant; pH 6.5, N2O;
2-carboxy-ethylsulfanyl
40055-90-1

2-carboxy-ethylsulfanyl

trimeprazine semitartrate
4330-99-8

trimeprazine semitartrate

2C18H22N2S*C4H6O6*2H(1+)
1175-88-8, 2015-31-8, 4330-99-8, 14101-45-2, 21287-43-4, 39832-33-2, 66634-41-1

2C18H22N2S*C4H6O6*2H(1+)

Conditions
ConditionsYield
In water Rate constant; pH 6.5, N2O;
2-amino-2-carboxy-1,1-dimethyl-ethylsulfanyl
15784-30-2

2-amino-2-carboxy-1,1-dimethyl-ethylsulfanyl

trimeprazine semitartrate
4330-99-8

trimeprazine semitartrate

2C18H22N2S*C4H6O6*2H(1+)
1175-88-8, 2015-31-8, 4330-99-8, 14101-45-2, 21287-43-4, 39832-33-2, 66634-41-1

2C18H22N2S*C4H6O6*2H(1+)

Conditions
ConditionsYield
In water Rate constant; pH 6.5, N2O;
Cysteine thiyl radical
35772-84-0

Cysteine thiyl radical

trimeprazine semitartrate
4330-99-8

trimeprazine semitartrate

2C18H22N2S*C4H6O6*2H(1+)
1175-88-8, 2015-31-8, 4330-99-8, 14101-45-2, 21287-43-4, 39832-33-2, 66634-41-1

2C18H22N2S*C4H6O6*2H(1+)

Conditions
ConditionsYield
In water Rate constant; pH 6.5 (phosphate puffer), N2O;
glutathione thiyl radical
40055-99-0

glutathione thiyl radical

trimeprazine semitartrate
4330-99-8

trimeprazine semitartrate

2C18H22N2S*C4H6O6*2H(1+)
1175-88-8, 2015-31-8, 4330-99-8, 14101-45-2, 21287-43-4, 39832-33-2, 66634-41-1

2C18H22N2S*C4H6O6*2H(1+)

Conditions
ConditionsYield
In water Rate constant; pH 6.5, N2O;
trimeprazine semitartrate
4330-99-8

trimeprazine semitartrate

thiyl radical

thiyl radical

2C18H22N2S*C4H6O6*2H(1+)
1175-88-8, 2015-31-8, 4330-99-8, 14101-45-2, 21287-43-4, 39832-33-2, 66634-41-1

2C18H22N2S*C4H6O6*2H(1+)

Conditions
ConditionsYield
In water pH 6.5;
trimeprazine semitartrate
4330-99-8

trimeprazine semitartrate

3H-phenothiazin-3-one

3H-phenothiazin-3-one

Conditions
ConditionsYield
With β‐cyclodextrin In phosphate buffer for 1h; pH=6.8; Kinetics; Further Variations:; pH-values; Reagents; UV-irradiation;

Trimeprazine tartrate Chemical Properties

Molecular Structure:

Molecular Formula: C40H50N4O6S2
Molecular Weight: 746.978200000001
IUPAC Name: (2R,3R)-2,3-Dihydroxybutanedioic acid; N,N,2-trimethyl-3-phenothiazin-10-ylpropan-1-amine
Synonyms of Trimeprazine tartrate (CAS NO.4330-99-8): 10-(3-(Dimethylamino)-2-methylpropyl)phenothiazine tartrate (2:1) ; 10H-Phenothiazine-10-propanamine N,N,beta-trimethyl-, (R-(R*,R*))-2,3-dihydroxybutanedioate (2:1) ; Alimemazin (RR)-tartrat ; Alimemazine tartrate ; Bayer 1219 ; EINECS 224-368-9 ; Nedeltran ; Panectyl ; RP 6549 ; Repeltin ; SKF 5277 ; Temaril ; Therafene ; Theralen ; Theralene ; UNII-362NW1LD6Z ; Vallergan ; Vanectyl ; Phenothiazine, 10-(3-(dimethylamino)-2-methylpropyl)-, tartrate (2:1)
CAS NO: 4330-99-8
Product Categories: Antipruritic ; Drug / Therapeutic Agent ; Histamine Agents ; Histamine Antagonists ; Histamine H1 Antagonists ; Neurotransmitter Agents

Trimeprazine tartrate Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 140mg/kg (140mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 57, 1972.
mouse LD50 intravenous 33mg/kg (33mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 57, 1972.
mouse LD50 oral 300mg/kg (300mg/kg)   Drugs in Japan Vol. 6, Pg. 41, 1982.
rat LD50 intraperitoneal 110mg/kg (110mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 57, 1972.
rat LD50 intravenous 35mg/kg (35mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 57, 1972.
rat LD50 oral 210mg/kg (210mg/kg)   "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972Vol. -, Pg. 57, 1972.

Trimeprazine tartrate Safety Profile

Hazard Codes of Trimeprazine tartrate (CAS NO.4330-99-8): HarmfulXn
Risk Statements: 20/21/22 
R20/21/22: Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements: 36 
S36: Wear suitable protective clothing.
RIDADR: 3249
RTECS: SO6475000
HazardClass: 6.1(b)
PackingGroup: III

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