Triptolide supplier | CasNO.38748-32-2

Name
Triptolide
EINECS 300-006-3
CAS No. 38748-32-2
Article Data9
CAS DataBase
Density 1.48 g/cm³
Solubility soluble in DMSO
Melting Point 226-227 °C
Formula C₂₀H₂₄O₆
Boiling Point 601.7 °C at 760 mmHg
Molecular Weight 360.407
Flash Point 220.7 °C
Transport Information
Appearance White crystalline solid
Safety 22-24/25
Risk Codes
Molecular Structure
Hazard Symbols
Synonyms (-)-Triptolide;NSC 163062;PG 490;[3bS-(3ba,4aa,5aR*,6b,6ab,7ab,7ba,8aR*,8bb)]-3b,4,4a,6,6a,7a,7b,8b,9,10-Decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)trisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-1(3H)-one;
PSA 84.12000
LogP 1.10310

Triptolide Chemical Properties

Name : Triptolide

Molecular Structure :

Molecular Formula : C₂₀H₂₄O₆
Molecular Weight : 360.41
CAS Registry Number : 38748-32-2
storage temp : 2-8°C
form : solid
solubility :soluble
color :white to off-white
Triptolide is a traditional Chinese medicine-derived inhibitor of polycystic kidney disease Triptolide is a potent, biologically active compound isolated from the medicinal 'Thunder God Vine' Tripterygium wilfordii Hook F. The TCM tea Lei Gong Teng made from this plant has been used for centuries, as a therapeutic against cancer, inflammation, and auto-immune diseases. Crews and colleagues showed that triptolide causes cell growth arrest in certain cell types.

Triptolide Uses

Diterpenoid triepoxide with immunosuppressant
antitumor properties

Triptolide Toxicity Data With Reference

1.	ipr-mus LD50:900 µg/kg	CYLPDN Zhongguo Yaoli Xuebao. Acta Pharmacologica Sinica. 2 (1981),70.
2.	ivn-mus LD50:800 µg/kg	CYLPDN Zhongguo Yaoli Xuebao. Acta Pharmacologica Sinica. 2 (1981),70.
3.	ivn-dog LDLo:160 µg/kg	CYLPDN Zhongguo Yaoli Xuebao. Acta Pharmacologica Sinica. 2 (1981),70.

Triptolide Safety Profile

Poison by intravenous and intraperitoneal routes. When heated to decomposition it emits acrid smoke and irritating fumes.

Product Name

Triptolide

Triptolide Chemical Properties

Triptolide Uses

Triptolide Toxicity Data With Reference

Triptolide Safety Profile

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