Product Name

  • Name

    TROMANTADINEHYDROCHLORIDE

  • EINECS
  • CAS No. 31635-40-2
  • Density g/cm3
  • Solubility
  • Melting Point
  • Formula C16H28 N2 O2 . Cl H
  • Boiling Point 356.4°Cat760mmHg
  • Molecular Weight 316.92
  • Flash Point 169.4°C
  • Transport Information
  • Appearance
  • Safety Poison by ingestion and intravenous route. See also AMINES. When heated to decomposition it emits very toxic fumes of NOx and HCl. An antiviral agent.
  • Risk Codes
  • Molecular Structure Molecular Structure of 31635-40-2 (TROMANTADINEHYDROCHLORIDE)
  • Hazard Symbols
  • Synonyms Acetamide,N-1-adamantyl-N-[2-(dimethylamino)ethoxy]-, monohydrochloride (8CI); Acetamide,N-[2-(dimethylamino)ethoxy]-N-tricyclo[3.3.1.13,7]dec-1-yl-, monohydrochloride(9CI)
  • PSA 32.78000
  • LogP 3.09890

Tromantadine hydrochloride Chemical Properties

Product Name: Tromantadine hydrochloride (CAS NO.31635-40-2)


Molecular Formula: C16H28N2O2•ClH
Molecular Weight: 316.92g/mol
Mol File: 31635-40-2.mol
Boiling point: 356.4 °C at 760 mmHg
Flash Point: 169.4 °C
Enthalpy of Vaporization: 60.17 kJ/mol
Vapour Pressure: 2.93E-05 mmHg at 25°C
XLogP3-AA:
H-Bond Donor: 1
H-Bond Acceptor: 3
Structure Descriptors of Tromantadine hydrochloride (CAS NO.31635-40-2):
  IUPAC Name: N-(1-adamantyl)-N-(2-dimethylaminoethyloxy)acetamide hydrochloride
  Canonical SMILES: CC(=O)N(C12CC3CC(C1)CC(C3)C2)OCCN(C)C.Cl
  InChI: InChI=1S/C16H28N2O2.ClH/c1-12(19)18(20-5-4-17(2)3)16-9-13-6-14(10-16)8-15(7-13)11-16;/h13-15H,4-11H2,1-3H3;1H 
  InChIKey: XIGPZPFNRMQMGT-UHFFFAOYSA-N

Tromantadine hydrochloride Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 oral 170mg/kg (170mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: ATAXIA		 Arzneimittel-Forschung. Drug Research. Vol. 23, Pg. 577, 1973.
mouse LD50 intravenous 71mg/kg (71mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD		 Arzneimittel-Forschung. Drug Research. Vol. 23, Pg. 577, 1973.
rabbit LD50 skin > 20gm/kg (20000mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 23, Pg. 577, 1973.
rat LD50 oral 630mg/kg (630mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

BEHAVIORAL: ATAXIA		 Arzneimittel-Forschung. Drug Research. Vol. 23, Pg. 577, 1973.

Tromantadine hydrochloride Safety Profile

Poison by ingestion and intravenous route. See also AMINES. When heated to decomposition it emits very toxic fumes of NOx and HCl. An antiviral agent.

Tromantadine hydrochloride Specification

 Tromantadine hydrochloride ,its CAS NO. is 31635-40-2,the synonyms is 1-(Dimethylaminoethoxyacetamido)adamantane hydrochloride ; D 41 ; N-1-Adamantyl-N-(2-(dimethylamino)ethoxy)acetamide hydrochloride ; Viru-merz ; Acetamide, N-1-adamantyl-N-(2-(dimethylamino)ethoxy)-, hydrochloride .

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