Troparil supplier | CasNO.74163-84-1

Name
Troparil
EINECS
CAS No. 74163-84-1
Article Data3
CAS DataBase
Density 1.099g/cm³
Solubility
Melting Point
Formula C16H21 N O2
Boiling Point 350.2°C at 760 mmHg
Molecular Weight 259.348
Flash Point 121.3°C
Transport Information
Appearance
Safety
Risk Codes
Molecular Structure
Hazard Symbols
Synonyms 8-Azabicyclo[3.2.1]octane-2-carboxylicacid, 8-methyl-3-phenyl-, methyl ester, (exo,exo)-;(?à)-WIN 35065;Troparil;Win 35065;
PSA 29.54000
LogP 2.36380

Troparil Specification

Troparil(also known as (–)-2β-Carbomethoxy-3β-phenyltropane, WIN 35,065-2, or β-CPT) is a stimulant drug used in scientific research. With the CAS NO.74163-84-1, Troparil is a phenyltropane based dopamine reuptake inhibitor (DRI) and is derived from methylecgonidine. The most commonly used form of troparil is the tartrate salt, but the hydrochloride and naphthalenedisulfonate salts are also available, as well as the free base.

Physical properties about Troparil are: (1)ACD/LogP: 1.564; (2)ACD/LogD (pH 5.5): -1.52; (3)ACD/LogD (pH 7.4): -0.88; (4)ACD/BCF (pH 5.5): 1.00; (5)ACD/BCF (pH 7.4): 1.00; (6)ACD/KOC (pH 5.5):1.00; (7)ACD/KOC (pH 7.4): 1.00; (8)#H bond acceptors: 3; (9)#Freely Rotating Bonds: 3; (10)Index of Refraction: 1.54; (11)Molar Refractivity: 74.004 cm³; (12)Molar Volume: 235.801 cm³; (13)Polarizability: 29.337 10-24cm³; (14)Surface Tension: 38.9329986572266 dyne/cm; (15)Density: 1.1 g/cm³; (16)Flash Point: 121.251 °C; (17)Enthalpy of Vaporization: 59.478 kJ/mol; (18)Boiling Point: 350.203 °C at 760 mmHg

You can still convert the following datas into molecular structure:
(1)InChI=1S/C16H21NO2/c1-17-12-8-9-14(17)15(16(18)19-2)13(10-12)11-6-4-3-5-7-11/h3-7,12-15H,8-10H2,1-2H3;
(2)InChIKey=OMBOXYLBBHNWHL-UHFFFAOYSA-N;
(3)Smilesc1([C@@H]2[C@@H]([C@@H]3[N@@](C)[C@@H](C2)CC3)C(OC)=O)ccccc1

The toxicity data is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intraperitoneal	185mg/kg (185mg/kg)		Farmakologiya i Toksikologiya Vol. 48(1), Pg. 15, 1985.
mouse	LD50	intravenous	50mg/kg (50mg/kg)	BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)	Russian Pharmacology and Toxicology Vol. 48, Pg. 26, 1985.

Product Name

Troparil

Troparil Specification

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