Conditions | Yield |
---|---|
With N-ethylmorpholine buffer; phosphorotriimidazolide at 22℃; for 72h; other 5'-nucleotides, also with phosphorotribenzimidazolide, MnCl2; other time, temperature; | A 25% B 36% |
With phosphorotriimidazolide; magnesium chloride at 22℃; for 72h; N-ethylmorpholine buffer (pH 7.0); | A 25% B 36% |
UTP
Conditions | Yield |
---|---|
With pyridine; water; iodine In N,N-dimethyl-formamide at 20℃; for 2.25h; | 9.3% |
Conditions | Yield |
---|---|
durch Biosynthese; |
Conditions | Yield |
---|---|
reversible enzymatische Bildung mit Hilfe von wss. Nucleosidmonophosphat-kinase aus Hefe-Praeparaten; | |
reversible enzymatische Bildung mit Hilfe von wss. Nucleosidmonophosphat-kinase aus Leber-Praeparaten; | |
reversible enzymatische Bildung mit Hilfe von wss. Nucleosidmonophosphat-kinase aus Erbsen-Samen; |
uridine 5'-(2-deoxy-α-D-glucopyranosyl diphosphate)
A
2-deoxy-α-D-glucopyranosyl
B
UTP
Conditions | Yield |
---|---|
With sodium pyrophosphate; uridine-5'-diphosphoglucose pyrophosohorylase; 2-amino-2-hydroxymethyl-1,3-propanediol; magnesium chloride; bovine serum albumin In water at 25℃; for 72h; |
Conditions | Yield |
---|---|
With UDPG pyrophosphorylase In water at 25℃; for 4h; Equilibrium constant; pH 7.2; |
Conditions | Yield |
---|---|
With polyphosphate; Escherichia coli polyphosphate kinase; tris hydrochloride In water at 37℃; for 16h; | 49.6 % Chromat. |
With rabbit muscle pyruvate kinase; potassium chloride; phosphoenolpyruvic acid; D,L-dithiothreitol at 20℃; pH=7.5; Kinetics; Concentration; Reagent/catalyst; Tris buffer; |
UTP
Conditions | Yield |
---|---|
With pyrophosphoric acid mit Hilfe von Glucose-1-phosphat-uridylyltransferase; |
UTP
Conditions | Yield |
---|---|
With acetonitrile anschl. mit m-Kresol und anschl. Hydrieren an Palladium/Kohle in wss. Aethanol und Behandeln mit wss. LiOH; |
Conditions | Yield |
---|---|
durch enzymatische Bildung mit Hilfe von Pyruvatkinase aus Kaninchenmuskelgewebe; |
Conditions | Yield |
---|---|
reversible enzymatische Bildung mit Hilfe von wss. Nucleosiddiphosphat-kinase aus Hefe-Praeparaten und tierischen Gewebeextrakten; | |
reversible enzymatische Bildung mit Hilfe von wss. Nucleosiddiphosphat-kinase aus Erbsen-Samen; |
Conditions | Yield |
---|---|
With sodium hydroxide; potassium phosphate; nuclease P1; PAN-immobilized PNPase; phospho(enol)pyruvic acid mono potassium salt; magnesium chloride; manganese(ll) chloride 1.) water, 50 deg C, 1 h, 2.) room temperature, 4 days; Yield given. Multistep reaction. Yields of byproduct given; |
Conditions | Yield |
---|---|
With magnesium oxide at 140 - 145℃; in wss. Loesung (pH 8 -8.5) und Behandeln des Nucleosid-Gemisches in wss. Loesung (pH ca. 7) in Gegenwart von Hefe und Dextrose mit NaH2PO4 und Na2HPO4; |
Conditions | Yield |
---|---|
With pyridine; tributyl-amine; phosphoric acid | |
With pyridine; phosphoric acid |
UTP
Conditions | Yield |
---|---|
With tris(tetra-n-butylammonium) hydrogen pyrophosphate In tetrahydrofuran at 20℃; for 0.5h; | 45 mg |
2',3'-O-(methoxymethylidene)uridine
UTP
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1: 690 mg / N-methylimidazole; pyridine / tetrahydrofuran / 20 °C 2: LiHMDS / tetrahydrofuran / 2 h / -78 - 0 °C 3: 215 mg / aq. HCl / acetonitrile / 4 h / 20 °C / pH 2.0 4: H2 / Pd/C / tetrahydrofuran / 2 h / 20 °C 5: 45 mg / tris(tetra-n-butylammonium) hydrogen pyrophosphate / tetrahydrofuran / 0.5 h / 20 °C View Scheme |
UTP
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 215 mg / aq. HCl / acetonitrile / 4 h / 20 °C / pH 2.0 2: H2 / Pd/C / tetrahydrofuran / 2 h / 20 °C 3: 45 mg / tris(tetra-n-butylammonium) hydrogen pyrophosphate / tetrahydrofuran / 0.5 h / 20 °C View Scheme |
5'-uridyl benzyl N-methyl-N-(4-chlorobutyl)phosphoramidate
UTP
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: H2 / Pd/C / tetrahydrofuran / 2 h / 20 °C 2: 45 mg / tris(tetra-n-butylammonium) hydrogen pyrophosphate / tetrahydrofuran / 0.5 h / 20 °C View Scheme |
(4-Chloro-butyl)-methyl-phosphoramidic acid benzotriazol-1-yl ester (3aR,4R,6R,6aR)-6-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-methoxy-tetrahydro-furo[3,4-d][1,3]dioxol-4-ylmethyl ester
UTP
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: LiHMDS / tetrahydrofuran / 2 h / -78 - 0 °C 2: 215 mg / aq. HCl / acetonitrile / 4 h / 20 °C / pH 2.0 3: H2 / Pd/C / tetrahydrofuran / 2 h / 20 °C 4: 45 mg / tris(tetra-n-butylammonium) hydrogen pyrophosphate / tetrahydrofuran / 0.5 h / 20 °C View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: pyridine; chlorophosphoric acid dibenzyl ester / -40 - -30 °C / anschl. Hydrierung 2: aqueous H3PO4; aqueous pyridine View Scheme |
Conditions | Yield |
---|---|
With tributyl-amine; bis(tri-n-butylammonium) pyrophosphate In N,N-dimethyl-formamide at -15℃; for 2h; | A n/a B 107 mg |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: trichlorophosphate / trimethyl phosphite / 2 h / -15 °C 2: tributyl-amine; bis(tri-n-butylammonium) pyrophosphate / N,N-dimethyl-formamide / 2 h / -15 °C View Scheme |
uridine 5'-diphospho-N-acetylglucosamine
UTP
Conditions | Yield |
---|---|
With pyrophosphate tetraanion; recombinant Arabidopsis N-acetylglucosamine-1-phosphate uridylyltransferase-1; magnesium chloride at 37℃; for 0.166667h; pH=7.6; Kinetics; Concentration; Reagent/catalyst; aq. buffer; Enzymatic reaction; |
uridine-5'-diphospho-N-acetyl-D-galactosamine
B
UTP
Conditions | Yield |
---|---|
With pyrophosphate tetraanion; recombinant Arabidopsis N-acetylglucosamine-1-phosphate uridylyltransferase-1; magnesium chloride at 37℃; for 0.166667h; pH=7.6; Kinetics; Reagent/catalyst; Concentration; aq. buffer; Enzymatic reaction; |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: N,N-dimethyl-formamide / 1.5 h / 20 °C / Inert atmosphere 2: pyridine; iodine; water / N,N-dimethyl-formamide / 2.25 h / 20 °C View Scheme |
Conditions | Yield |
---|---|
With Pasteurella multocida inorganic pyrophosphatase; Bifidobacterium longumuridine 5'-diphosphate-sugarpyrophosphorylase; adenosine-5'-triphosphate; magnesium chloride In aq. buffer at 37℃; for 2h; pH=8; Enzymatic reaction; | 99% |
With Glucose-1-phosphate thymidylyltransferase from Streptococcus pneumonia serotype 23F; magnesium chloride at 37℃; for 1h; Enzymatic reaction; | 94% |
With GalU; α(1->3) galactotransferase; α(1->4) galactotransferase; manganese(ll) chloride at 37℃; for 48h; pH=7; Inert atmosphere; aq. buffer; Enzymatic reaction; | 70% |
Conditions | Yield |
---|---|
With recombinant human GalNAc kinase GK2; recombinant human UDP-GalNAc pyrophosphorylase AGX1; ATP; yeast inorganic pyrophosphatase In various solvent(s) at 37℃; pH=8.8; | 99% |
Conditions | Yield |
---|---|
With recombinant Bifidobacterium longum ATCC55813 UDP-sugar pyrophosphorylase; recombinant Pasteurella multocida P-1059 inorganic pyrophosphatase; magnesium chloride at 37℃; for 2h; pH=8; aq. buffer; Enzymatic reaction; | 99% |
With yeast inorganic pyrophosphatase; recombinant Arabidopsis N-acetylglucosamine-1-phosphate uridylyltransferase-2; magnesium chloride at 37℃; for 0.166667h; pH=7.6; aq. buffer; Enzymatic reaction; |
N-acetylglucosamine-1-phosphate
UTP
uridine 5'-diphospho-N-acetylglucosamine
Conditions | Yield |
---|---|
With yeast inorganic pyrophosphatase; N-acetylglucosamine-1-phosphate pyrophosphorylase from C. jejuni NCTC 11168; tris hydrochloride; magnesium chloride at 37℃; for 2h; pH=7.5; | 97.9% |
With Pyrococcus furiosus enzyme; magnesium(II) In various solvent(s) at 80℃; pH=7.5; Enzyme kinetics; | |
With Pyrococcus furious enzyme; magnesium(II) In various solvent(s) at 80℃; for 1h; pH=7.5; |
2-trifluoroacetamido-2-deoxy-α,β-D-glucopyranose
UTP
uridine 5'-diphospho-2-deoxy-2-trifluoroacetamido-α-D-glucopyranoside
Conditions | Yield |
---|---|
With inorganic pyrophosphatase cloned from Pasteurella multocida strain P-1059; N-acetylglucosamine-1-phosphate uridylyltransferase cloned from Pasteurella multocida strain P-1059 (ATCC15742); N-acetylhexosamine 1-kinase cloned from Bifidobacterium longum ATCC55813; ATP; magnesium chloride In water at 37℃; pH=8; aq. buffer; Enzymatic reaction; | 97% |
With hydrogenchloride; N-acetylglucosamine-1-phosphate uridylyltransferase from Escherichia coli K12 MG1655; pyrophosphatase from Escherichia coli K12 MG1655; recombinant N-acetylhexosamine 1-kinase; ATP; magnesium chloride In aq. buffer at 37℃; pH=8.5; Concentration; Temperature; pH-value; Enzymatic reaction; | |
With inorganic pyrophosphatase from P. multocida; N-acetyl hexosamine 1-kinase from Bifidobacterium infantis; UDP-N-acetylgalactosamine pyrophosphorylase from Pasteurella multocida; ATP; sodium hydroxide; magnesium chloride In aq. buffer at 37℃; for 24h; pH=7; Enzymatic reaction; |
UTP
Conditions | Yield |
---|---|
With pyrophosphatase from C. cerevisiae; uridyl transferase GlmU from E. coli K12; magnesium chloride In aq. buffer at 37℃; for 24h; pH=7.5; Enzymatic reaction; | 95% |
UTP
Conditions | Yield |
---|---|
With pyrophosphatase from C. cerevisiae; uridyl transferase GlmU from E. coli K12; magnesium chloride; D,L-dithiothreitol In aq. buffer at 37℃; for 24h; pH=7.5; Enzymatic reaction; | 93% |
2-deoxy-2-fluoro-D-mannopyranoside
UTP
uridine 5'-diphospho-2-fluoro-2-deoxy-α-D-mannopyranoside
Conditions | Yield |
---|---|
With recombinant Bifidobacterium infantis ATCC15697 N-acetylhexosamine 1-kinase; recombinant Bifidobacterium longum ATCC55813 UDP-sugar pyrophosphorylase; recombinant Pasteurella multocida P-1059 inorganic pyrophosphatase; ATP; magnesium chloride at 37℃; for 24h; pH=8; aq. buffer; Enzymatic reaction; | 92% |
Conditions | Yield |
---|---|
With ATP; magnesium chloride In aq. buffer at 37℃; for 36h; | 92% |
Conditions | Yield |
---|---|
With inorganic pyrophosphatase; recombinant thymidylyltransferase from Aneurinibacillus thermoaerophilus DSM 10155; magnesium chloride at 55℃; for 1.5h; pH=7.5; Inert atmosphere; aq. buffer; Enzymatic reaction; | 90% |
With Glucose-1-phosphate thymidylyltransferase from Streptococcus pneumonia serotype 23F for 48h; Enzymatic reaction; | 86% |
With phosphate buffer; UDPG-PPase from Pyrococcus furiosus DSM 3638 at 90℃; pH=7.5; Enzyme kinetics; |
2-azido-2-deoxy-D-mannopyranose
UTP
uridine 5'-diphospho-2-azido-2-deoxy-α-D-mannopyranoside
Conditions | Yield |
---|---|
With recombinant Bifidobacterium infantis ATCC15697 N-acetylhexosamine 1-kinase; recombinant Bifidobacterium longum ATCC55813 UDP-sugar pyrophosphorylase; recombinant Pasteurella multocida P-1059 inorganic pyrophosphatase; ATP; magnesium chloride at 37℃; for 24h; pH=8; aq. buffer; Enzymatic reaction; | 90% |
Conditions | Yield |
---|---|
With glucuronokinase from Arabidopsis thaliana; pyrophosphatase from E. coli; UDP-sugar pyrophosphorylasegene from Arabidopsis thaliana; ATP; magnesium chloride In aq. buffer at 37℃; pH=8; Enzymatic reaction; | 89% |
Conditions | Yield |
---|---|
With recombinant Bifidobacterium longum ATCC55813 UDP-sugar pyrophosphorylase; recombinant Escherichia coli K-12 galactokinase; recombinant Pasteurella multocida P-1059 inorganic pyrophosphatase; ATP; magnesium chloride at 37℃; for 24h; pH=8; aq. buffer; Enzymatic reaction; | 86% |
With Pasteurella multocida inorganic pyrophosphatase; Bifidobacterium longumuridine 5'-diphosphate-sugarpyrophosphorylase; Echerichia coli galactokinase; adenosine-5'-triphosphate; magnesium chloride In aq. buffer at 37℃; for 24h; pH=8; Reagent/catalyst; Enzymatic reaction; | 86% |
With pyrophosphatase; Streptococcus pneumoniae TIGR4 galactokinase; Arabidopsis thaliana uridine-diphosphate-sugar pyrophosphorylase; ATP; magnesium chloride In aq. buffer at 42℃; for 1h; pH=8; Enzymatic reaction; | |
With galactokinase from Bifidobacterium infantis; inorganic pyrophosphatase from P. multocida; UDP-sugar pyrophosphorylase from Arabidopsis thaliana; ATP; sodium hydroxide; magnesium chloride In aq. buffer at 37℃; for 24h; pH=7.5; Enzymatic reaction; |
UTP
Conditions | Yield |
---|---|
With pyrophosphatase from C. cerevisiae; uridyl transferase GlmU from E. coli K12; magnesium chloride In aq. buffer at 37℃; for 24h; pH=7.5; Enzymatic reaction; | 86% |
UTP
P'-[2-(acetylamino)-2-deoxy-α-D-glucopyranosyl] ester uridine 5'-(trihydrogen diphosphate), disodium salt
Conditions | Yield |
---|---|
With 1,4-dithio-D,L-threitol; magnesium chloride at 30℃; for 3h; pH=7; aq. buffer; Enzymatic reaction; | 85% |
UTP
Conditions | Yield |
---|---|
With pyrophosphatase from C. cerevisiae; uridyl transferase GlmU from E. coli K12; magnesium chloride In aq. buffer at 37℃; for 48h; pH=7.5; Enzymatic reaction; | 84% |
N-acetyl-D-galactosamine
UTP
uridine 5'-diphospho-2-acetamido-2-deoxy-α-D-glacopyranoside
Conditions | Yield |
---|---|
With Pasteurella multocida inorganic pyrophosphatase; Pasteurella multocida N-acetylglucosamine-1-phosphate uridylyltransferase; adenosine-5'-triphosphate; MTESNEVLFGIASHFALEGAVTGIEPYGDGHINTTYLVTTDGPRYILQQMNTSIFPDTVNLMRNVELVTSTLKAQGKETLDIVPTTSGATWAEIDGGAWRVYKFIEHTMSYNLVPNPDVFREAGSAFGDFQNFLSEFDASQLTETIAHFHDTPHRFEDFKAALAADKLGRAAACCPEIDFYLSHADQYAVVMDGLRDGSIPLRVTHNDTKLNNILMDATTGKARAIIDLDTIMPGSMLFDFGDSIRFGASTALEDERDLSKVHFSTELFRAYTEGFVGELRGSITAREAELLPFSGNLLTMECGMRFLADYLEGDIYFATKYPEHNLVRTRTQIKLVQEMEQKASETHAIVADIMEAARLE; magnesium chloride In water at 37℃; for 24h; pH=8; Enzymatic reaction; | 83% |
With recombinant human GalNAc kinase GK2; recombinant human UDP-GalNAc pyrophosphorylase AGX1; ATP; yeast inorganic pyrophosphatase In various solvent(s) at 37℃; for 6h; pH=8.8; | 68% |
With pyrophosphatase; N-acetylhexosamine kinase; GalNAc pyrophosphorylase; ATP In aq. buffer at 37℃; pH=7.5; Enzymatic reaction; | |
With Bifidobacterium longum subsp. longum N-acetylhexosamine 1-kinase; Escherichia coli N-acetylglucosamine 1-phosphate uridyltransferase; ATP; sodium hydroxide; magnesium chloride In aq. buffer at 37℃; for 7h; pH=8.5; Inert atmosphere; Enzymatic reaction; |
N-Acetyl-D-glucosamine
UTP
uridine 5'-diphospho-N-acetylglucosamine
Conditions | Yield |
---|---|
With inorganic pyrophosphatase cloned from Pasteurella multocida strain P-1059; N-acetylglucosamine-1-phosphate uridylyltransferase cloned from Pasteurella multocida strain P-1059 (ATCC15742); N-acetylhexosamine 1-kinase cloned from Bifidobacterium longum ATCC55813; ATP; magnesium chloride In water at 37℃; pH=8; aq. buffer; Enzymatic reaction; | 81% |
With Pasteurella multocida inorganic pyrophosphatase; Pasteurella multocida N-acetylglucosamine-1-phosphate uridylyltransferase; adenosine-5'-triphosphate; MTESNEVLFGIASHFALEGAVTGIEPYGDGHINTTYLVTTDGPRYILQQMNTSIFPDTVNLMRNVELVTSTLKAQGKETLDIVPTTSGATWAEIDGGAWRVYKFIEHTMSYNLVPNPDVFREAGSAFGDFQNFLSEFDASQLTETIAHFHDTPHRFEDFKAALAADKLGRAAACCPEIDFYLSHADQYAVVMDGLRDGSIPLRVTHNDTKLNNILMDATTGKARAIIDLDTIMPGSMLFDFGDSIRFGASTALEDERDLSKVHFSTELFRAYTEGFVGELRGSITAREAELLPFSGNLLTMECGMRFLADYLEGDIYFATKYPEHNLVRTRTQIKLVQEMEQKASETHAIVADIMEAARLE; magnesium chloride In aq. buffer at 37℃; Enzymatic reaction; | 81% |
With inorganic pyrophosphatase; glucose-1-phosphate thymidylyltransferase from Aneurinibacillus thermoaerophilus DSM10155; N-acetylhexosamine kinase from Bifidobacterium longum; ATP; magnesium chloride In aq. buffer at 37 - 55℃; for 4h; pH=7.5; Enzymatic reaction; | |
With hydrogenchloride; N-acetylglucosamine-1-phosphate uridylyltransferase from Escherichia coli K12 MG1655; pyrophosphatase from Escherichia coli K12 MG1655; recombinant N-acetylhexosamine 1-kinase; ATP; magnesium chloride In aq. buffer at 37℃; pH=8.5; Concentration; Temperature; pH-value; Enzymatic reaction; | |
With inorganic pyrophosphatase from P. multocida; N-acetyl hexosamine 1-kinase from Bifidobacterium infantis; UDP-N-acetylgalactosamine pyrophosphorylase from Pasteurella multocida; ATP; sodium hydroxide; magnesium chloride In aq. buffer at 37℃; for 24h; pH=7.5; Enzymatic reaction; |
UTP
5-Iodo-UTP
Conditions | Yield |
---|---|
With N-iodo-succinimide; sodium azide In water for 15h; regioselective reaction; | 80% |
With N-iodo-succinimide; sodium azide In water at 60℃; for 15h; regioselective reaction; | 79% |
Conditions | Yield |
---|---|
With recombinant Arabidopsis thaliana glucuronokinase; molecular weight around 42 kDa; recombinant Bifidobacterium longum UDP-sugar pyrophosphorylase; recombinant Pasteurella multocida inorganic pyrophosphatase; ATP; magnesium chloride In aq. buffer at 37℃; for 36h; pH=6.5; Catalytic behavior; Reagent/catalyst; pH-value; Enzymatic reaction; chemoselective reaction; | 80% |
With glucuronokinase from Arabidopsis thaliana; inorganic pyrophosphatase from P. multocida; UDP-sugar pyrophosphorylase from Arabidopsis thaliana; ATP; sodium hydroxide; magnesium chloride In aq. buffer at 37℃; for 24h; pH=7.5; Enzymatic reaction; |
UTP
Conditions | Yield |
---|---|
With yeast inorganic pyrophosphatase; N-acetylglucosamine-1-phosphate pyrophosphorylase from C. jejuni NCTC 11168; tris hydrochloride; magnesium chloride at 37℃; for 2h; pH=7.5; | 79.9% |
UTP
Conditions | Yield |
---|---|
With Glucose-1-phosphate thymidylyltransferase from Streptococcus pneumonia serotype 23F for 48h; Enzymatic reaction; | 78% |
With phosphate buffer; UDPG-PPase from Pyrococcus furiosus DSM 3638 at 90℃; pH=7.5; Enzyme kinetics; | |
With phosphate buffer; UDPG-PPase from Pyrococcus furiosus DSM 3638; magnesium chloride at 90℃; for 0.5h; | 92 % Turnov. |
D-Galactose
UTP
Conditions | Yield |
---|---|
With galactokinase; pyruvate kinase; inorganic pyrophosphatase; phosphoenolpyruvic acid; galactose-1-phosphate uridylyltransferase; GalU; ATP; uridine-5'-diphosphoglucose at 30℃; for 24h; pH=8; aq. phosphate buffer; Inert atmosphere; | 78% |
With inorganic pyrophosphatase; galactokinase from Meiothermus taiwanensis; UDP-sugar pyrophosphorylase pyrophosphorylase from Arabidopsis thaliana; ATP; magnesium chloride In aq. buffer at 42℃; for 1h; pH=9; Enzymatic reaction; |
UTP
Conditions | Yield |
---|---|
With 1,4-dithio-D,L-threitol; magnesium chloride at 30℃; for 3h; pH=7; aq. buffer; Enzymatic reaction; | 78% |
adenosine 5'-phosphorimidazolide
UTP
Conditions | Yield |
---|---|
With H96F-Fhit; magnesium chloride In various solvent(s) at 20℃; for 1h; pH=5.5; | 73% |
UTP
uridine 5'-diphospho-2-acetamido-6-azido-2,6-dideoxy-α-D-glucopyranoside
Conditions | Yield |
---|---|
With inorganic pyrophosphatase cloned from Pasteurella multocida strain P-1059; N-acetylglucosamine-1-phosphate uridylyltransferase cloned from Pasteurella multocida strain P-1059 (ATCC15742); N-acetylhexosamine 1-kinase cloned from Bifidobacterium longum ATCC55813; ATP; magnesium chloride In water at 37℃; pH=8; aq. buffer; Enzymatic reaction; | 72% |
UDP-glucose
C6H13O8P
UTP
uridine-5'-diphospho-5-deoxy-D-galactofuranose
Conditions | Yield |
---|---|
With inorganic pyrophosphatase; UDP-glucose pyrophosphorylase; galactose-1-phosphate uridyltransferase | 71% |
2-butyramido-2-deoxy-α-D-glucopyranosyl phosphate
UTP
Conditions | Yield |
---|---|
With yeast inorganic pyrophosphatase; N-acetylglucosamine-1-phosphate pyrophosphorylase from C. jejuni NCTC 11168; tris hydrochloride; magnesium chloride at 37℃; for 2h; pH=7.5; | 70.6% |
Conditions | Yield |
---|---|
With inorganic pyrophosphatase; UDP-glucose pyrophosphorylase; galactose-1-phosphate uridyltransferase | 70% |
UTP
P'-[2-(acetylamino)-2-deoxy-α-D-galactopyranosyl] ester uridine 5'-(trihydrogen diphosphate), disodium salt
Conditions | Yield |
---|---|
With 1,4-dithio-D,L-threitol; magnesium chloride at 30℃; for 48h; pH=7; aq. buffer; Enzymatic reaction; | 70% |
IUPAC Name: [[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-Dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate
Empirical Formula: C9H15N2O15P3
Molecular Weight: 484.1411
Classification Code : Mutation data
Einecs: 200-558-7
Freely Rotating Bonds: 10
Polar Surface Area: 213.56 Å2
Index of Refraction: 1.643
Molar Refractivity: 83.19 cm3
Molar Volume: 229.8 cm3
Polarizability: 32.98 ×10-24 cm3
Surface Tension: 128.1 dyne/cm
Density: 2.106 g/cm3
The molecular structure of Uridine5'-(tetrahydrogen triphosphate) (CAS NO.63-39-8) is
.
Uridine5'-(tetrahydrogen triphosphate) (CAS NO.63-39-8) is used as organic intermediate.
Hazard Codes: Xn
Risk Statements: 20/21/22-68-20/21/22
R20/21/22: Harmful by inhalation, in contact with skin and if swallowed.
R68: Possible risk of irreversible effects.
Safety Statements: 22-26-36
S22: Do not breathe dust.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36: Wear suitable protective clothing.
WGK Germany: 1
The chemical synonyms of Uridine5'-(tetrahydrogen triphosphate) (CAS NO.63-39-8) are Uridine 5'-triphosphate ;Uridine 5'-triphosphoric acid ;Uridine triphosphate ;Uteplex .
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