Vamidothion supplier | CasNO.2275-23-2

Name
Vamidothion
EINECS 218-894-8
CAS No. 2275-23-2
Density 1.24 g/cm³
Solubility 4,000,000 mg l-1
Melting Point 43oC
Formula C8H18 N O4 P S2
Boiling Point °Cat760mmHg
Molecular Weight 287.341
Flash Point 2 ºC
Transport Information UN 2811
Appearance Colorless needles.
Safety Poison by ingestion and skin contact. Mutation data reported. When heated to decomposition it emits very toxic fumes of PO_x, SO_x, and NO_x.
Risk Codes R21;R25;R50
Molecular Structure
Hazard Symbols
Synonyms Phosphorothioicacid, O,O-dimethyl ester, S-ester with 2-[(2-mercaptoethyl)thio]-N-methylpropionamide(7CI,8CI); Dimethyl S-[2-(1-methylcarbamoylethylthio)ethyl] phosphorothiolate;Kilval; O,O-Dimethyl S-[2-(1-methylcarbamoylethylthio)ethyl] phosphorothioate;RP 9895; Vamidoate; Vamidothion; XMC
PSA 125.04000
LogP 2.37910

Vamidothion Chemical Properties

Chemistry informtion about N-Methyl-O,O-Dimethylthiolophos-Phoryl-5-Thia-3-Methyl-2-Valeramide (CAS NO.2275-23-2) is:
IUPAC Name: 2-(2-Dimethoxyphosphorylsulfanylethylsulfanyl)-N-Methylpropanamide
Synonyms: Vamidothion ; Vamidothion(Content>10%) ; 10465rp ; 2-(2-Dimethoxyphosphinoylthioethylthio)-N-Methylpropionamide ; Americancyanamid-43073 ; Dimethyls-(2-(1-Methylcarbamoylethylthio)Ethyl)Phosphorothiolate ; Ent26,613 ; N-Methyl-3-Thia-2-Methyl-Valeramiddero,O-Dimethylthiolphosphorsaeure
MF: C₈H₁₈NO₄PS₂
MW: 287.34
EINECS: 218-894-8
Density: 1.24 g/cm³
Flash Point: 2 °C
Storage temp.: 0-6°C
Following is the molecular structure of N-Methyl-O,O-Dimethylthiolophos-Phoryl-5-Thia-3-Methyl-2-Valeramide (CAS NO.2275-23-2) is:

Vamidothion Uses

N-Methyl-O,O-Dimethylthiolophos-Phoryl-5-Thia-3-Methyl-2-Valeramide (CAS NO.2275-23-2) is a systemic acaricide and insecticide.

Vamidothion Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
bird - wild	LD50	oral	35mg/kg (35mg/kg)		Pesticide Manual. Vol. 9, Pg. 856, 1991.
cat	LD50	unreported	117mg/kg (117mg/kg)	behavioral: ataxia behavioral: coma kidney, ureter, and bladder: urine volume increased	Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 41(3), Pg. 107, 1976.
dog	LD50	oral	110mg/kg (110mg/kg)		Guide to the Chemicals Used in Crop Protection. Vol. 6, Pg. 530, 1973.
guinea pig	LD50	oral	85mg/kg (85mg/kg)		Guide to the Chemicals Used in Crop Protection. Vol. 6, Pg. 530, 1973.
guinea pig	LD50	unreported	85mg/kg (85mg/kg)		"Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971Vol. -, Pg. 349, 1971.
mouse	LD50	oral	40mg/kg (40mg/kg)	behavioral: tremor behavioral: convulsions or effect on seizure threshold gastrointestinal: changes in structure or function of salivary glands	Meditsinskii Zhurnal Uzbekistana. Vol. (8), Pg. 65, 1972.
mouse	LD50	skin	1460mg/kg (1460mg/kg)		Yakkyoku. Pharmacy. Vol. 37, Pg. 1621, 1986.
mouse	LD50	unreported	43mg/kg (43mg/kg)		"Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971Vol. -, Pg. 349, 1971.
rabbit	LD50	oral	160mg/kg (160mg/kg)		Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 14(2), Pg. 58, 1970.
rabbit	LD50	skin	1160mg/kg (1160mg/kg)		World Review of Pest Control. Vol. 9, Pg. 119, 1970.
rat	LC50	inhalation	1730mg/m3/4H (1730mg/m3)		Pesticide Manual. Vol. 9, Pg. 856, 1991.
rat	LD50	oral	64mg/kg (64mg/kg)		"Pesticide Index," Frear, E.H., ed., State College, PA, College Science Pub., 1969Vol. 5, Pg. 233, 1976.
rat	LD50	unreported	64mg/kg (64mg/kg)		"Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971Vol. -, Pg. 349, 1971.

Vamidothion Consensus Reports

EPA Genetic Toxicology Program.

Vamidothion Safety Profile

Poison by ingestion and skin contact. Mutation data reported. When heated to decomposition it emits very toxic fumes of PO_x, SO_x, and NO_x.
Hazard Codes:
Toxic T
Dangerous N
Harmful Xn
Flammable F
Risk Statements:
R21:Harmful in contact with skin.
R25 :Toxic if swallowed.
R50:Very toxic to aquatic organisms.
R36:Irritating to eyes.
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
R11:Highly flammable.
Safety Statements:
S36/37:Wear suitable protective clothing and gloves.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.
S16:Keep away from sources of ignition.
RIDADR: UN 2811
RTECS: TF7900000
HazardClass: 6.1(b)
PackingGroup: III

Vamidothion Specification

N-Methyl-O,O-Dimethylthiolophos-Phoryl-5-Thia-3-Methyl-2-Valeramide (CAS NO.2275-23-2) is a colorless needles.
First Aid Measures:
Ingestion: Seek medical assistance.
Inhalation: Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
Skin: Systemic effects can occur from dermal exposure to organophosphates. Remove contaminated clothing, wash skin, hair and nails vigorously with repeated soap washings. Leather absorbs pesticides; all contaminated leather should be discarded. Rescue personnel and bystanders should avoid direct contact with contaminated skin, clothing, or other objects. Treatment should include recommendations listed in the oral exposure section when appropriate.
Eyes: Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility. Patients symptomatic following exposure should be observed in a controlled setting until all signs and symptoms have fully resolved. Treatment should include recommendations listed in the oral exposure section when appropriate.
Handling and Storage:
Storage: Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling: All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.

Product Name

Vamidothion