Conditions | Yield |
---|---|
With mercury(II) diacetate; boric acid at 10 - 20℃; | |
With hydroquinone; mercury(II) oxide at 60℃; dann bei 40-50grad; | |
With mercury(II) oxide |
Conditions | Yield |
---|---|
for 1h; Ambient temperature; |
vinyl chloroacetate
Conditions | Yield |
---|---|
With benzene |
Conditions | Yield |
---|---|
With Cp*2Sm(THF)2 In toluene Ambient temperature; further reagent: SmI2; | 99% |
With 1,3-dichlorotetrabutyldistannoxane at 50℃; for 17h; | 96% |
With 1,3-dichlorotetrabutyldistannoxane at 50℃; for 17h; | 96% |
vinyl chloroacetate
1-phenyl-2-cyclohex-2-en-1-ol
Conditions | Yield |
---|---|
With Candida antartica lipase B (CAL-B) immobilized on a support (commercial name: Chirazyme L-2 C4); V-MPS4 In acetonitrile at 35℃; for 24h; Inert atmosphere; | 99% |
Conditions | Yield |
---|---|
With Candida antarctica lipase B In 2,2,4-trimethylpentane; acetone at 55℃; for 1h; Enzymatic reaction; regioselective reaction; | 99% |
vinyl chloroacetate
thexyldimethylsilyl 6-O-acetyl-β-D-galactopyranosyl-(1->3)-6-O-acetyl-2-azido-2-deoxy-β-D-glucopyranoside
Conditions | Yield |
---|---|
With Candida antarctica lipase In acetonitrile at 40℃; for 12h; Acylation; | 91% |
thexyldimethylsilyl 6-O-acetyl-β-D-galactopyranosyl-(1->3)-2-azido-2-deoxy-β-D-glucopyranoside
Conditions | Yield |
---|---|
With Candida antarctica lipase In acetonitrile at 28℃; for 4h; Acylation; | 90% |
vinyl chloroacetate
(3S,5S)-1-ethynyl-3,5-dihydroxy-2-methylcyclohex-1-ene
Conditions | Yield |
---|---|
In tetrahydrofuran for 23h; Ambient temperature; Chromobacterium viscosum lipase; | A 86% B 7 % Spectr. |
vinyl chloroacetate
(3R,5R)-1-ethynyl-3,5-dihydroxy-2-methylcyclohex-1-ene
Conditions | Yield |
---|---|
In tetrahydrofuran for 92h; Ambient temperature; Chromobacterium viscosum lipase; | A 6.5% B 2.5% C 85% |
2-Hydroxy-1,4-naphthoquinone
vinyl chloroacetate
tert-butylisonitrile
Conditions | Yield |
---|---|
With 1,4-diaza-bicyclo[2.2.2]octane In isopropyl alcohol at 120℃; for 0.166667h; Microwave irradiation; | 85% |
vinyl chloroacetate
vinyl iodoacetate
Conditions | Yield |
---|---|
With sodium iodide In acetone at 20℃; for 1h; | 85% |
6-Monoacetylated D-glucal
vinyl chloroacetate
6-O-acetyl-3-O-chloroacetyl-glucal
Conditions | Yield |
---|---|
With lipase from Pseudomonas fluorescens In 1,2-dimethoxyethane for 3h; Ambient temperature; | 83% |
vinyl chloroacetate
tert-butylisonitrile
Conditions | Yield |
---|---|
With 1,4-diaza-bicyclo[2.2.2]octane In isopropyl alcohol at 120℃; for 0.166667h; Microwave irradiation; | 83% |
vinyl chloroacetate
6-O-Benzoyl-D-glucal
6-O-benzoyl-3-O-chloroacetyl-glucal
Conditions | Yield |
---|---|
With lipase from Pseudomonas fluorescens In 1,2-dimethoxyethane for 2h; Ambient temperature; | 82% |
6-Monoacetylated D-glucal
vinyl chloroacetate
6-O-acetyl-3-O-chloroacetyl-glucal
Conditions | Yield |
---|---|
In 1,2-dimethoxyethane | 80% |
vinyl chloroacetate
1-O-acetyl-2,6-anhydro-5-deoxy-D-arabino-hex-5-enitol
6-O-acetyl-3-O-chloroacetyl-galactal
Conditions | Yield |
---|---|
In 1,2-dimethoxyethane | 80% |
benzyl 4-O-β-D-galactopyranosyl-β-D-glucopyranoside
vinyl chloroacetate
benzyl (6-O-chloroacetyl-β-D-galactopyranosyl)-(1->4)-β-D-glucopyranoside
Conditions | Yield |
---|---|
With lipase from Candida antarctica In tetrahydrofuran at 20℃; for 48h; Acylation; Enzymatic reaction; | 78% |
With immobilized Candida antarctica lipase In tetrahydrofuran at 40℃; for 48h; | 78% |
Conditions | Yield |
---|---|
With tert-butyl methyl ether; 4 A molecular sieve; Novo Lipozyme IM-20 for 160h; Ambient temperature; | 74.7% |
vinyl chloroacetate
(3R,5S)-1-ethynyl-3,5-dihydroxy-2-methylcyclohex-1-ene
Conditions | Yield |
---|---|
In tetrahydrofuran for 21h; Ambient temperature; Chromobacterium viscosum lipase; Yields of byproduct given; | A 71% B n/a |
In tetrahydrofuran for 21h; Ambient temperature; Chromobacterium viscosum lipase; Yield given; | A 71% B n/a |
vinyl chloroacetate
(3S,5R)-1-ethynyl-3,5-dihydroxy-2-methylcyclohex-1-ene
Conditions | Yield |
---|---|
In tetrahydrofuran at 45℃; for 45h; Chromobacterium viscosum lipase; Yields of byproduct given; | A 70% B n/a |
In tetrahydrofuran at 45℃; for 45h; Chromobacterium viscosum lipase; Yield given; | A 70% B n/a |
vinyl chloroacetate
thexyldimethylsilyl 6-O-acetyl-β-D-galactopyranosyl-(1->3)-2-azido-2-deoxy-β-D-glucopyranoside
Conditions | Yield |
---|---|
With Candida antarctica lipase In acetonitrile at 35℃; for 1h; Acylation; | A 67% B 29% |
Conditions | Yield |
---|---|
In diethyl ether at 20℃; for 22.5h; Schlenk technique; | 63% |
In benzene |
vinyl chloroacetate
benzyl (6-O-acetyl-β-D-galactopyranosyl)-(1->4)-β-D-glucopyranoside
Conditions | Yield |
---|---|
With immobilized Candida antarctica lipase In acetonitrile at 45℃; for 120h; | 62% |
2-[2-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-cyclopent-3-enol
A
(1S,2R)-2-[2-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-cyclopent-3-enol
Conditions | Yield |
---|---|
With Lipase PS In di-isopropyl ether at 30℃; for 1h; | A 50% B 46% |
vinyl chloroacetate
Conditions | Yield |
---|---|
With Porcine pancreas lipase type II In 1,4-dioxane at 20℃; for 24h; Enzymatic reaction; | 50% |
vinyl chloroacetate
(4-hydroxy-3,4-dihydroquinolin-1(2H)-yl)(phenyl)methanone
Conditions | Yield |
---|---|
With Novozyme 435 lipase In tert-butyl methyl ether at 30℃; for 8h; Enzymatic reaction; enantioselective reaction; | A 49% B 34% |
vinyl chloroacetate
Conditions | Yield |
---|---|
With Novozyme 435 lipase In tert-butyl methyl ether at 30℃; for 8h; Enzymatic reaction; enantioselective reaction; | A 42% B 48% |
vinyl chloroacetate
Conditions | Yield |
---|---|
With Novozyme 435 lipase In tert-butyl methyl ether at 30℃; for 8h; Enzymatic reaction; enantioselective reaction; | A 47% B 29% |
vinyl chloroacetate
Conditions | Yield |
---|---|
With Novozyme 435 lipase In tert-butyl methyl ether at 30℃; for 8h; Enzymatic reaction; enantioselective reaction; | A 43% B 46% |
The Vinyl chloroacetate with the CAS number 2549-51-1 is also called Acetic acid, 2-chloro-,ethenyl ester. The IUPAC name is ethenyl 2-chloroacetate. Its molecular formula is C4H5ClO2. The EINECS registry number is 219-834-3. This chemical belongs to the following product categories: (1)C2 to C5; (2)Carbonyl Compounds; (3)Esters.
The properties of the chemical are: (1)ACD/LogP: 0.96; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 0.96; (4)ACD/LogD (pH 7.4): 0.96; (5)ACD/BCF (pH 5.5): 3.17; (6)ACD/BCF (pH 7.4): 3.17; (7)ACD/KOC (pH 5.5): 79.53; (8)ACD/KOC (pH 7.4): 79.53; (9)#H bond acceptors: 2; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 3; (12)Polar Surface Area: 26.3 Å2; (13)Index of Refraction: 1.428; (14)Molar Refractivity: 26.92 cm3; (15)Molar Volume: 104.5 cm3; (16)Polarizability: 10.67×10-24cm3; (17)Surface Tension: 29.4 dyne/cm; (18)Enthalpy of Vaporization: 36.17 kJ/mol; (19)Vapour Pressure: 13.2 mmHg at 25°C.
Uses: This chemical can react with octan-1-ol to prepare chloro-acetic acid octyl ester. This reaction needs reagent 1,3-dichlorotetrabutyldistannoxane at temperature of 50°C. The reaction time is 17 hours. The yield is 96%.
While using this chemical, you should be very cautious. This chemical is flammable and harmful by inhalation, in contact with skin and if swallowed. It can cause burns.. Therefore, you should take the following instructions. Firstly, you should wear suitable protective clothing, gloves and eye/face protection. Then in case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice. Finally in case of accident or if you feel unwell, you should seek medical advice immediately (show the label whenever possible).
You can still convert the following datas into molecular structure:
(1)SMILES: ClCC(=O)O\C=C
(2)InChI: InChI=1/C4H5ClO2/c1-2-7-4(6)3-5/h2H,1,3H2
(3)InChIKey: XJELOQYISYPGDX-UHFFFAOYAH
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View