Product Name

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  • Name

    (R)-dimethyl(1-methyl-4-oxo-3,3-diphenylhexyl)ammonium chloride

  • EINECS
  • CAS No. 5967-73-7
  • Article Data5
  • CAS DataBase
  • Density
  • Solubility
  • Melting Point 220-227°C
  • Formula C21H27 N O . Cl H
  • Boiling Point 423.7°C at 760 mmHg
  • Molecular Weight 345.912
  • Flash Point 126.5°C
  • Transport Information
  • Appearance
  • Safety Poison by intravenous, subcutaneous, and intraperitoneal routes. Human systemic effects by ingestion: hallucinations, distorted perceptions, and analgesia. Caution: Abuse leads to habituation or addiction. When heated to decomposition it emits very toxic fumes of Cl− and NOx. See also METHADONE HYDROCHLORIDE.
  • Risk Codes
  • Molecular Structure Molecular Structure of 5967-73-7 ((R)-dimethyl(1-methyl-4-oxo-3,3-diphenylhexyl)ammonium chloride)
  • Hazard Symbols
  • Synonyms 3-Heptanone,6-(dimethylamino)-4,4-diphenyl-, hydrochloride, (-)- (8CI); 3-Heptanone,6-(dimethylamino)-4,4-diphenyl-, hydrochloride, (6R)- (9CI); 3-Heptanone,6-(dimethylamino)-4,4-diphenyl-, hydrochloride, (R)-; (-)-Methadonehydrochloride; D-(-)-Methadone hydrochloride; Levomethadone hydrochloride;Levorotatory methadone hydrochloride;l-6-Dimethylamino-4,4-diphenyl-3-heptanone hydrochloride; l-Methadonehydrochloride; l-Polamidon hydrochloride
  • PSA 20.31000
  • LogP 5.09400

l-Methadone hydrochloride Chemical Properties

IUPAC Name: (6R)-6-(Dimethylamino)-4,4-diphenylheptan-3-one hydrochloride
Synonyms: (-)-6-(Dimethylamino)-4,4-diphenyl-3-heptanone Hydrochloride ; (R)-6-(Dimethylamino)-4,4-diphenyl-3-heptanone Hydrochloride ; Levadone ; L-Polamidon
CAS NO: 5967-73-7
Molecular Formula of l-Methadone hydrochloride (CAS NO.5967-73-7) :C21H28ClNO
Molecular Weight of l-Methadone hydrochloride (CAS NO.5967-73-7) : 345.90612
Molecular Structure of l-Methadone hydrochloride (CAS NO.5967-73-7) :
EINECS: 227-756-6
Mol File: 5967-73-7.mol
Flash Point: 126.5 °C
Enthalpy of Vaporization: 67.8 kJ/mol
Boiling Point: 423.7 °C at 760 mmHg
Vapour Pressure: 2.2E-07 mmHg at 25°C

l-Methadone hydrochloride Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
human TDLo oral 44ug/kg (0.044mg/kg) BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS"

BEHAVIORAL: ANALGESIA		 Journal of Pharmacology and Experimental Therapeutics. Vol. 93, Pg. 282, 1948.
mouse LD50 intraperitoneal 30mg/kg (30mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 98, Pg. 305, 1950.
mouse LD50 intravenous 18mg/kg (18mg/kg) BEHAVIORAL: ANALGESIA Acta Physiologica Academiae Scientiarum Hungaricae. Vol. 4, Pg. 363, 1953.
mouse LD50 oral 97300ug/kg (97.3mg/kg)   Journal of Organic Chemistry. Vol. 17, Pg. 321, 1952.
mouse LD50 parenteral 6483ug/kg (6.483mg/kg) BEHAVIORAL: ANALGESIA Journal of Pharmacology and Experimental Therapeutics. Vol. 145, Pg. 11, 1964.
mouse LD50 subcutaneous 19mg/kg (19mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 98, Pg. 305, 1950.
rat LD50 intraperitoneal 24mg/kg (24mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 98, Pg. 305, 1950.
rat LD50 subcutaneous 20mg/kg (20mg/kg) ENDOCRINE: OTHER CHANGES British Journal of Pharmacology and Chemotherapy. Vol. 10, Pg. 260, 1955.

 

l-Methadone hydrochloride Safety Profile

Poison by intravenous, subcutaneous, and intraperitoneal routes. Human systemic effects by ingestion: hallucinations, distorted perceptions, and analgesia. Caution: Abuse leads to habituation or addiction. When heated to decomposition it emits very toxic fumes of Cl− and NOx. See also METHADONE HYDROCHLORIDE.

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