O-ANISIDINE HYDROCHLORIDE

IUPAC Name: 2-Methoxyaniline hydrochloride
Synonyms of o-Anisidine hydrochloride (CAS NO.134-29-2): 2-Aminoanisole hydrochloride ; 2-Anisidine hydrochloride ; 2-Methoxy-1-aminobenzene hydrochloride ; 2-Methoxyaniline hydrochloride ; 2-Methoxybenzenamine hydrochloride ; o-Aminoanisole hydrochloride ; o-Anisylamine hydrochloride ; o-Methoxyphenylamine hydrochloride ; Benzenamine, 2-methoxy-, hydrochloride
InChI: InChI=1/C7H9NO.ClH/c1-9-7-5-3-2-4-6(7)8;/h2-5H,8H2,1H3;1H
InChIKey: XCZCWGVXRBJCCD-UHFFFAOYAX
Std. InChI: InChI=1S/C7H9NO.ClH/c1-9-7-5-3-2-4-6(7)8;/h2-5H,8H2,1H3;1H
Std. InChIKey: XCZCWGVXRBJCCD-UHFFFAOYSA-N
Product Categories: Anilines, Aromatic Amines and Nitro Compounds
CAS NO: 134-29-2
Molecular Formula: C₇H₁₀ClNO
Molecular Weight: 159.6134
Molecular Structure :
H bond acceptors: 2
H bond donors: 2
Freely Rotating Bonds: 2
Polar Surface Area: 12.47 Å²
Flash Point: 98.9 °C
Enthalpy of Vaporization: 46.15 kJ/mol
Boiling Point: 225 °C at 760 mmHg
Vapour Pressure: 0.0885 mmHg at 25°C
Water solubility: O-Anisidine hydrochloride (CAS NO.134-29-2) is water soluble.
Appearance: Gray-black crystalline solid or light gray powder.

NTP 10th Report on Carcinogens. IARC Cancer Review: Group 2B IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 (1987),p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Sufficient Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 27 (1982),p. 63.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human No Adequate Data IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 27 (1982),p. 63.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . NCI Carcinogenesis Bioassay (feed); Clear Evidence: mouse, rat NCITR*    National Cancer Institute Carcinogenesis Technical Report Series. (Bethesda, MD 20014) No. NCI-CG-TR-89 ,1978. . Community Right-To-Know List.

Risk Statements: 36/37/38
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36/37/39
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.
RTECS: BZ6500000
Confirmed carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Mutation data reported. When heated to decomposition it emits very toxic fumes of NO_x and HCl.

 O-Anisidine hydrochloride (CAS NO.134-29-2) may be carcinogenic. It reacts as an acid to neutralize bases. These neutralizations generate some heat, usually does not react as either oxidizing agents or reducing agents but such behavior is not impossible.It  may catalyze organic reactions.