ALPHA-AMANITIN

The α-Amanitin, with the CAS registry number 23109-05-9, is also known as alpha-Amanitin. α-Amanitin is a cyclic peptide of eight amino acids. And it is found in several species of the Amanita genus of mushrooms.α-Amanitin is an inhibitor of RNA polymerase II. And this mechanism makes it a deadly toxin. In addition, α-Amanitin can also be used to determine which types of RNA polymerase are present. This is done by testing the sensitivity of the polymerase in the presence of α-Amanitin. It belongs to the product categories of Alkaloids; DNA-RNA Transcription Regulators Cell Signaling and Neuroscience;  Enzyme Inhibitors; Enzyme Inhibitors by Type; Miscellaneous Enzyme. Its EINECS registry number is 245-432-2. This chemical's molecular formula is C₃₉H₅₄N₁₀O₁₄S and molecular weight is 918.97. In addition, this chemical's classification codes are Enzyme Inhibitors; Mutation Data; Natural Product; Noxae; Nucleic Acid Synthesis Inhibitors; Poisons. Besides, it must be stored at -20 °C.

Physical properties about α-Amanitin are: (1)# of Rule of 5 Violations: 3; (2)ACD/BCF (pH 5.5): 1; (3)ACD/BCF (pH 7.4): 1; (4)ACD/KOC (pH 5.5): 1; (5)ACD/KOC (pH 7.4): 1; (6)#H bond acceptors: 24; (7)#H bond donors: 14; (8)#Freely Rotating Bonds: 11; (9)Polar Surface Area: 400.09 Å²; (10)Index of Refraction: 1.694; (11)Molar Refractivity: 224.556 cm³; (12)Molar Volume: 584.734 cm³; (13)Polarizability: 89.021×10^-24 cm³; (14)Surface Tension: 98.295 dyne/cm; (15)Density: 1.572 g/cm³; (16)Flash Point: 934.862 °C; (17)Enthalpy of Vaporization: 266.529 kJ/mol; (18)Boiling Point: 1622.182 °C at 760 mmHg; (19)Vapour Pressure: 0 mmHg at 25 °C.

When you are using this chemical, please be cautious about it as the following:
As a chemical, it is very toxic by inhalation, in contact with skin and if swallowed. And it has danger of cumulative effects. During using it, wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell seek medical advice immediately (show the label where possible).

You can still convert the following datas into molecular structure:
(1) SMILES: CC[C@@H](C)[C@H]1C(=O)NCC(=O)N[C@H]2C[S@@](=O)c3c(c4ccc(cc4[nH]3)O)C[C@@H](C(=O)NCC(=O)N1)NC(=O)[C@@H](NC(=O)[C@@H]5C[C@H](CN5C(=O)[C@@H](NC2=O)CC(=O)N)O)[C@@H](C)[C@H](CO)O
(2) InChI: InChI=1/C39H54N10O14S/c1-4-16(2)31-36(60)42-11-29(55)43-25-15-64(63)38-21(20-6-5-18(51)7-22(20)46-38)9-23(33(57)41-12-30(56)47-31)44-37(61)32(17(3)27(53)14-50)48-35(59)26-8-19(52)13-49(26)39(62)24(10-28(40)54)45-34(25)58/h5-7,16-17,19,23-27,31-32,46,50-53H,4,8-15H2,1-3H3,(H2,40,54)(H,41,57)(H,42,60)(H,43,55)(H,44,61)(H,45,58)(H,47,56)(H,48,59)/t16-,17+,19-,23+,24+,25+,26+,27+,31+,32+,64-/m1/s1
(3) InChIKey: CIORWBWIBBPXCG-BBORFGEJBV