Pazopanib Hydrochlo...

Pazopanib Hydrochloride (CAS: 635702-64-6)

Pazopanib Hydrochloride (CAS: 635702-64-6)

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100 Gram

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  • Min.Order :100 Gram
  • Purity: 99
  • Payment Terms : L/C,T/T,

Keywords

raw material API anticancer

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  • Appearance:
  • Application:Anticancer Raw Material
  • PackAge:Aluminum Foil Bag or Fiber Drum
  • ProductionCapacity:100|Metric Ton|Month
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  • Transportation:EMS

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Pazopanib Hydrochloride (CAS: 635702-64-6)
 
Chemical Information
Product Name Pazopanib Hydrochloride  
Molecular Formula C21H24ClN7O2S  
Molecular Weight 473.98  
Purity: 99%+
Product Specifications: Pharmaceutical Grade 
MOQ(Minimum Order Quantity): 100g
Payment: L/C, T/T,
Shipment: EMS, DHL, FedEx, TNT  
Brand: Newbio Pharm-Tech  
 
Description 
Pazopanib HCl (GW786034 HCl) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM in cell-free assays, respectively.
Pazopanib potently inhibits VEGF-induced phosphorylation of VEGFR2 in HUVEC cells with IC50 of 8 nM. Pazopanib shows dose-dependent growth inhibition in all synovial sarcoma cell lines including SYO-1 and HS-SY-II cells.
 

 

Details:

Pazopanib Hydrochloride (CAS: 635702-64-6)
 
Chemical Information
Product Name Pazopanib Hydrochloride  
Molecular Formula C21H24ClN7O2S  
Molecular Weight 473.98  
Purity: 99%+
Product Specifications: Pharmaceutical Grade 
MOQ(Minimum Order Quantity): 100g
Payment: L/C, T/T,
Shipment: EMS, DHL, FedEx, TNT  
Brand: Newbio Pharm-Tech  
 
Description 
Pazopanib HCl (GW786034 HCl) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM in cell-free assays, respectively.
Pazopanib potently inhibits VEGF-induced phosphorylation of VEGFR2 in HUVEC cells with IC50 of 8 nM. Pazopanib shows dose-dependent growth inhibition in all synovial sarcoma cell lines including SYO-1 and HS-SY-II cells.
 

 

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