Gefitinib Hydrochlo...

Gefitinib Hydrochloride (CAS: 184475-55-6)

Gefitinib Hydrochloride (CAS: 184475-55-6)

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100 Gram

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  • Min.Order :100 Gram
  • Purity: 99
  • Payment Terms : L/C,T/T,

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raw material API anticancer

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  • Appearance:
  • Application:Anticancer Raw Material
  • PackAge:Aluminum Foil Bag or Fiber Drum
  • ProductionCapacity:100|Metric Ton|Month
  • Storage:
  • Transportation:EMS

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Gefitinib Hydrochloride (CAS: 184475-55-6)
 
Chemical Information
Product Name Gefitinib hydrochloride 
Molecular Formula C22H25Cl2FN4O3 
Molecular Weight 483.36 
Purity: 99%+
Product Specifications: Pharmaceutical Grade 
MOQ(Minimum Order Quantity): 100g
Payment: L/C, T/T,
Shipment: EMS, DHL, FedEx, TNT  
Brand: Newbio Pharm-Tech  
 
Description 
Gefitinib (ZD-1839, Iressa) is an Epidermal Growth Factor Receptor-selective Tyrosine Kinase Inhibitor.
Gefitinib inhibited colony formation in soft agar in a dose dependent manner in all cancer cell lines. However, treatment with higher doses resulted in a 2-4-fold increases in apoptosis. Dose-dependent supra-additive increase in growth inhibition was observed when cancer cells were treated with totoxic drugs and Gefitinib. The combined treatment markedly enhanced apoptotic cell death induced by single agent treatment.
Gefitinib treatment of nude mice bearing established human GEO colon cancer xenografts revealed a reversible dose-dependent inhibition of tumor growth because GEO tumors resumed the growth rate of controls at the end of the treatment.
 

 

Details:

Gefitinib Hydrochloride (CAS: 184475-55-6)
 
Chemical Information
Product Name Gefitinib hydrochloride 
Molecular Formula C22H25Cl2FN4O3 
Molecular Weight 483.36 
Purity: 99%+
Product Specifications: Pharmaceutical Grade 
MOQ(Minimum Order Quantity): 100g
Payment: L/C, T/T,
Shipment: EMS, DHL, FedEx, TNT  
Brand: Newbio Pharm-Tech  
 
Description 
Gefitinib (ZD-1839, Iressa) is an Epidermal Growth Factor Receptor-selective Tyrosine Kinase Inhibitor.
Gefitinib inhibited colony formation in soft agar in a dose dependent manner in all cancer cell lines. However, treatment with higher doses resulted in a 2-4-fold increases in apoptosis. Dose-dependent supra-additive increase in growth inhibition was observed when cancer cells were treated with totoxic drugs and Gefitinib. The combined treatment markedly enhanced apoptotic cell death induced by single agent treatment.
Gefitinib treatment of nude mice bearing established human GEO colon cancer xenografts revealed a reversible dose-dependent inhibition of tumor growth because GEO tumors resumed the growth rate of controls at the end of the treatment.
 

 

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