Details:

  Zirconium Phosphate (α-ZrP)

Also :  Zirconium Hydrogen Phosphate                                                                   

Chemical Formula:  α-Zr（HPO4）2·H2O                                                    

CAS No. :             13772-29-7                                                                         

Form & Appearance :   White Powder                                                            

Molecular  Weight: :    301.19                                                                    

Packing： Aluminum foil bag 

Application : Hemodialyzer, Silver-based antimicrobial material, Catalyst, Biological engineering, optics, Drug delivery, Refractory material, Fine ceramics, Nuclear waste management 

Quick Details:

Classification: Phosphate
Type: inorganical chemical
CAS No.: 13772-29-7
Other Names: Zirconium Hydrogen Phosphate
MF: Zr(HPO4)2.H2O
EINECS No.: 13772-29-7
Place of Origin: Sichuan, China (Mainland)
Grade Standard: Agriculture Grade, Food Grade, Industrial Grade
Purity: 99%min
Appearance: White Powder
Application: Industrial
Brand Name: YAOLONG
Model Number: ZP01
ZrO2: 40(Max%)
Fluoride: 0.002(Max%)
Water insoluble: Water insoluble
lgnition loss: 6(Max%)
PH: 5-7
Density: 2.66(g/cm3)
Average partical size: 1.1~1.7


Product Details                                                              
 
 Zirconium phosphate is acidic, insoluble in water nor organic solvents,inorganic cation exchange material that has a layered structure. Zirconium phosphate has high thermal and chemical stability, solid state ion conductivity, resistance to ionizing radiation,and the capacity to incorporate different types of  molecules with different sizes between their layers.
 

Product Application

Hemodialyzer, Silver-based antimicrobial material, Catalyst, Drug delivery,Refractory material, Fine ceramics, Nuclear waste management
Analytical Value Typical Specifications


What is Zirconium                                                                                                                                                            
1. Zirconium is a chemical element with symbol Zr and atomic number 40. The name of zirconium is taken from the name of the mineral zircon, the most important source of zirconium.
2.  Zirconium is a lustrous, greyish-white, soft, ductile and malleable metal which is solid at room temperature, though it becomes hard and brittle at lower purities.
3.  Zirconium is a by-product of the mining and processing of the titanium minerals ilmenite and rutile, as well astin mining.
 

Why Choose Us
 
1. 15 year's trading and manufacturing experience
2. High quality raw material from ILUKA  
3. Strict quality control and steady product performance 
4. Competitive price
5. Prompt delivery
 
Drug Delivery System

Co-internalization of DOX and ZrP nanoparticles into the cytoplasm and nucleus of MCF-7 cells was detected using CM. A high fluorescence in cell nucleus demonstrated DOX release from ZrP nanoparticles. ZrP alone is non-toxic to MCF-7 and MCF-10A cells. After a 48-hour treatment of MCF-7 cells with DOX:ZrP or DOX alone the IC50 obtained was 23M and 24 M, respectively. DOX cytotoxicity to MCF-7 cells after 72-hour treatment was three times higher than DOX:ZrP with IC50 of 0.74 M and 3.15 M, respectively. Conclusion: ZrP nanoparticles are internalized and can effectively deliver DOX to the interior of cancer cells. ZrP nanoparticles might provide a versatile platform for transportation of anticancer agents resulting in improved cancer therapy by reducing the side effects.

Nanoparticle as Drug Carrier

Cisplatin has been shown to be active against ovarian and testicular cancer, Hodgkin's lymphoma, and certain other malignancies. Its clinical effectiveness is limited by significant side effects and the emergence of drug resistance. Delivery of anticancer drugs such as cisplatin to the tumor cells without damaging healthy organs or tissues is highly difficult if not impossible. In the last several years nanoparticle-mediated drug delivery is being studied as a novel valuable mean for overcoming this problem. A novel nanoparticle intercalated formulation of cisplatin on a layered matrix of zirconium phosphate (ZrP) has been developed. It was expected that cisplatin, while being excluded from the external medium within ZrP layers will remain biologically inactive and that cisplatin will be released selectively in the tumor cell.

Sunshine Factory:                                                     

     Sunshine factory Co., Ltd. Is an established company with many years of exprience. We manufacture all our products in our factry. Our laboratory provides the highest quality. Our factory is located in Sichuan China.
 
Contact Information:

Sunshine Factory Co.,Ltd.
Add: Room 703, Air International Plaza, Yizhou Avenue, Chengdu, China
Zip code: 610041
Contact name : Amber
T: +86-28-8535-3648 | M: +86-15328075451| Skype: amber.pu2
Email: amberpu@yaolongchem.com
Web: www.yaolongchem.com
     #