Offer 81-25-4 98.0%...

Offer 81-25-4 98.0% global trader

Offer 81-25-4 98.0% global trader

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25 Kilogram

Negotiable

  • Min.Order :25 Kilogram
  • Purity: HPLC≥98.0%
  • Payment Terms : L/C,T/T

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81-25-4 98.0% global trader 81-25-4 Offer 81-25-4

Quick Details

  • Appearance:powder
  • Application:Effect and use: increase blood lipid content, raise blood pressure, relieve cough, strengthen heart, and strong hemolysis, anti-inflammatory effect.
  • PackAge:25KG/Drum 1KG/Bag
  • ProductionCapacity:8000|Kilogram|Day
  • Storage:Keep in closed vessel & store in room temperature
  • Transportation:

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Offer 81-25-4 98.0% global trader 
Quick Details
CAS No.:
81-25-4
Other Names:
Cholic acid
MF:
C24H40O5
EINECS No.:
201-337-8
Place of Origin:
Changde, Hunan, China (Mainland)
Type:
Gastrointestinal Agents
Grade Standard:
Medicine Grade
Usage:
Animal Pharmaceuticals
Brand Name:
Fousi
Model Number:
81-25-4
Purity:
99%min
Product Name:
Cholic acid
melting point:
200-201 °C(lit.)
CAS:
81-25-4
Molecular Weight:
408.57
Appearance:
powder
 
 

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Product name  Cholic acid
CAS number 81-25-4
MF C24H40O5
Acidity coefficient (pKa) 4.98(at 20℃)
condition of storage Store at RT.
solubility methanol: 0.1 g/mL, clear
Flash point

9℃

Description 
Cholic acid, also known as 3α,7α,12α-trihydroxy-5β-cholan-24-oic acid is a primary bile acid that is insoluble in water (soluble in alcohol and acetic acid), it is a white crystalline substance. Salts of cholic acid are called cholates. Cholic acid, along with chenodeoxycholic acid, is one of the two major bile acids produced by the liver, where it is synthesized from cholesterol. These two major bile acids are roughly equal in concentration in humans. Derivatives are made from cholyl-CoA, which exchanges its CoA with either glycine, or taurine, yielding glycocholic and taurocholic acid, respectively.
Cholic acid downregulates cholesterol-7-α-hydroxylase (rate-limiting step in bile acid synthesis), and cholesterol does the opposite. This is why chenodeoxycholic acid, and not cholic acid, can be used to treat gallstones (because decreasing bile acid synthesis would supersaturate the stones even more).
Cholic acid and chenodeoxycholic acid are the most important human bile acids. Other species may synthesize different bile acids as their predominant primary bile acids.
Cholic acid, formulated as Cholbam capsules, is approved by the United States Food and Drug Administration as a treatment for children and adults with bile acid synthesis disorders due to single enzyme defects, and for peroxisomal disorders (such as Zellweger syndrome).

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Offer 81-25-4 98.0% global trader 

 
Cholic acid Basic information
Chemical properties Uses Identification test Analysis of the content Toxicity Production methods
Product Name: Cholic acid
Synonyms: Ursodeoxycholic Acid EP Impurity B;(4R)-4-((3R,5S,7R,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid;3,7,12-Trihydroxy-cholan-24-oic acid;Cholic acid from pure ox bile;Cholic acid from bovine and sheep;Chenodeoxycholic Acid Impurity 2;5beta-Cholan-24-oic acid, 3alpha,7alpha,12alpha-trihydroxy-;Cholan-24-oic acid, 3,7,12-trihydroxy-, (3alpha,5beta,7alpha,12alpha)-
CAS: 81-25-4
MF: C24H40O5
MW: 408.57
EINECS: 201-337-8
Product Categories: chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Steroids
Mol File: 81-25-4.mol
Cholic acid Structure
Cholic acid Chemical Properties
Melting point  200-201 °C(lit.)
alpha  36 º (c=0.6, 95% EtOH)
Boiling point  449.08°C (rough estimate)
density  1.0310 (rough estimate)
refractive index  1.5800 (estimate)
Fp  9℃
storage temp.  Store at RT.
solubility  methanol: 0.1 g/mL, clear
pka 4.98(at 20℃)
Water Solubility  0.28 g/L (15 ºC)
Merck  14,2203
BRN  2822009
CAS DataBase Reference 81-25-4(CAS DataBase Reference)
NIST Chemistry Reference Cholic acid(81-25-4)
EPA Substance Registry System Cholan-24-oic acid, 3,7,12-trihydroxy-, (3.alpha.,5.beta.,7.alpha., 12.alpha.)-(81-25-4)
 
Safety Information
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  24/25-36-26
RIDADR  UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany  2
RTECS  FZ9350000
TSCA  Yes
Hazardous Substances Data 81-25-4(Hazardous Substances Data)
MSDS Information
Provider Language
3alpha,7alpha,12alpha-Trihydroxy-5beta-cholanic acid English
ACROS English
SigmaAldrich English
ALFA English

Changde Yungang Biotechnology Co., Ltd. is an export-oriented hi-tech enterprise; we are mainly engaged in the research, development, manufacturing and trade of pharmaceutical intermediates. Staring from the innovations of technology and product, Yungang is striving to develop new products and technologies; we are working hard for promoting its competitive force and sustainable developing capacity. Led by Deng Jiaguo (the founder and general manager of Yungang), we adopt the latest technologies to produce Ursodeoxycholic acid and chenodeoxycholic acid serial products. The preparation method of chenodeoxycholic acid has passed the authentication of technical achievement of our province and got several Chinese patents. At present, our Ursodeoxycholic acid can meet the standards of CP, USP and JP; Meanwhile, we also offer other specifications of products to customers with special requirements. Now, our main products including Ursodeoxycholic acid, chenodeoxycholic acid, Hyodeoxycholic acid, Cholic acid, Deoxycholic acid, Dehydrocholic acid and bacteria quarantine series such as bile salts of cow, bile salts 3, bile salts of fowl, cattle goll powder, bile powder of pig, deoxidization sodium cholate, and so on. Relying on the excellent strength of Chinese hi-tech enterprise and upholding such idea and culture spirit of "Honest, Unity, Be practical, be enterprising, be creative", we are working for customers' demands. Yungang looks forward to cooperating with you.

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